| 1 | Tue Nov 9 | vs TBD | W94-57 | 1-0 | 1.000 | - | | Alico Arena · Fort Myers, FL |
| 2 | Sat Nov 13 | at Loyola Chicago | L77-89 | 1-1 | .500 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 3 | Tue Nov 16 | vs #25USC | L61-78 | 1-2 | .333 | - | ESPNU | Alico Arena · Fort Myers, FL |
| 4 | Sun Nov 21 | vsTBD | W99-59 | 2-2 | .500 | - | | Alico Arena · Fort Myers, FL |
| 5 | Tue Nov 23 | vs Rhode Island | W67-66 | 3-2 | .600 | - | | Alico Arena · Fort Myers, FL |
| 6 | Fri Nov 26 | vs W Michigan | W77-67 | 4-2 | .667 | - | | Alico Arena · Fort Myers, FL |
| 7 | Sat Nov 27 | vs SE Louisiana | W90-71 | 5-2 | .714 | - | | Alico Arena · Fort Myers, FL |
| 8 | Sun Nov 28 | vs Purdue FW | W85-78 | 6-2 | .750 | - | | Alico Arena · Fort Myers, FL |
| 9 | Wed Dec 1 | at FIU | L61-77 | 6-3 | .667 | - | | Ocean Bank Convocation Center · Miami, FL |
| 10 | Sat Dec 4 | vs Dartmouth | W78-68 (OT) | 7-3 | .700 | - | | Alico Arena · Fort Myers, FL |
| 11 | Tue Dec 7 | at FAMU | W69-55 | 8-3 | .727 | - | | Al Lawson Center · Tallahassee, FL |
| 12 | Sat Dec 11 | at Robert Morris | W85-74 | 9-3 | .750 | - | | UPMC Events Center · Moon Township, PA |
| 13 | Sun Dec 19 | vs Mercer | W67-55 | 10-3 | .769 | - | | Alico Arena · Fort Myers, FL |
| 14 | Wed Dec 22 | at Canisius | L90-97 (OT) | 10-4 | .714 | - | | Koessler Athletic Center · Buffalo, NY |
| 15 | Wed Jan 5 | vs North Florida | W74-67 | 11-4 | .733 | - | | Alico Arena · Fort Myers, FL |
| 16 | Sat Jan 8 | at Jacksonville | L66-69 | 11-5 | .688 | - | | Swisher Gymnasium · Jacksonville, FL |
| 17 | Thu Jan 13 | at Kennesaw St | L53-77 | 11-6 | .647 | - | | KSU Convocation Center · Kennesaw, GA |
| 18 | Sat Jan 15 | vs Liberty | L75-78 | 11-7 | .611 | - | | Alico Arena · Fort Myers, FL |
| 19 | Tue Jan 18 | at Stetson | W93-91 (OT) | 12-7 | .632 | - | | Edmunds Center · Deland, FL |
| 20 | Sat Jan 22 | at J'Ville St | L71-79 | 12-8 | .600 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 21 | Thu Jan 27 | vs E Kentucky | W77-73 | 13-8 | .619 | - | | Alico Arena · Fort Myers, FL |
| 22 | Sat Jan 29 | vs Bellarmine | L63-74 | 13-9 | .591 | - | | Alico Arena · Fort Myers, FL |
| 23 | Thu Feb 3 | at C Arkansas | W95-93 (OT) | 14-9 | .609 | - | | Farris Center · Conway, AR |
| 24 | Sat Feb 5 | at Lipscomb | W77-68 | 15-9 | .625 | - | | Allen Arena · Nashville, TN |
| 25 | Wed Feb 9 | vs North Alabama | W92-60 | 16-9 | .640 | - | | Alico Arena · Fort Myers, FL |
| 26 | Sat Feb 12 | vsStetson | W89-82 (OT) | 17-9 | .654 | - | | Alico Arena · Fort Myers, FL |
| 27 | Wed Feb 16 | vsKennesaw St | W82-76 | 18-9 | .667 | - | | Alico Arena · Fort Myers, FL |
| 28 | Sat Feb 19 | atNorth Florida | L64-70 | 18-10 | .643 | - | | UNF Arena · Jacksonville, FL |
| 29 | Wed Feb 23 | atLiberty | W82-72 (OT) | 19-10 | .655 | - | | Liberty Arena · Lynchburg, VA |
| 30 | Sat Feb 26 | vsJacksonville | W76-69 | 20-10 | .667 | - | | Alico Arena · Fort Myers, FL |
| 31 | Tue Mar 1 | vsNorth Alabama | W81-72 | 21-10 | .677 | - | | Alico Arena · Fort Myers, FL |
| 32 | Thu Mar 3 | atBellarmine | L68-81 | 21-11 | .656 | - | | Knights Hall · Louisville, KY |
| 33 | Wed Mar 16 | vs Detroit Mercy | W95-79 | 22-11 | .667 | - | | Alico Arena · Fort Myers, FL |
| 34 | Mon Mar 21 | at Coast Car | L68-84 | 22-12 | .647 | - | | The HTC Center · Conway, SC |
