| 1 | Tue Nov 7 | at Indiana | L63-69 | 0-1 | .000 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 2 | Fri Nov 10 | vsTBD | W80-71 | 1-1 | .500 | - | | Alico Arena · Fort Myers, FL |
| 3 | Mon Nov 13 | atPitt | L74-86 | 1-2 | .333 | - | ACC Network | Petersen Events Center · Pittsburgh, PA |
| 4 | Fri Nov 17 | vsMissouri St | L61-70 | 1-3 | .250 | - | | Alico Arena · Fort Myers, FL |
| 5 | Sat Nov 18 | vsHampton | L85-92 | 1-4 | .200 | - | | Alico Arena · Fort Myers, FL |
| 6 | Mon Nov 20 | vsNorfolk St | L66-69 | 1-5 | .167 | - | | Alico Arena · Fort Myers, FL |
| 7 | Sat Nov 25 | vsUNC Wilmington | L55-71 | 1-6 | .143 | - | | Alico Arena · Fort Myers, FL |
| 8 | Wed Nov 29 | atFIU | W68-65 | 2-6 | .250 | - | CBSSN | Ocean Bank Convocation Center · Miami, FL |
| 9 | Sun Dec 3 | atCincinnati | L62-99 | 2-7 | .222 | - | | Fifth Third Arena · Cincinnati, OH |
| 10 | Tue Dec 5 | vsTBD | W87-54 | 3-7 | .300 | - | | Alico Arena · Fort Myers, FL |
| 11 | Sat Dec 9 | atMinnesota | L57-77 | 3-8 | .273 | - | BTN | Williams Arena · Minneapolis, MN |
| 12 | Sat Dec 16 | atMercer | L65-70 | 3-9 | .250 | - | | Hawkins Arena · Macon, GA |
| 13 | Tue Dec 19 | atGeorgia So | W53-42 | 4-9 | .308 | - | | W.S. Hanner Fieldhouse · Statesboro, GA |
| 14 | Fri Dec 22 | vsTBD | W78-75 (OT) | 5-9 | .357 | - | | Alico Arena · Fort Myers, FL |
| 15 | Sat Dec 30 | vs7FAU | W72-68 | 6-9 | .400 | - | | Alico Arena · Fort Myers, FL |
| 16 | Thu Jan 4 | vsJacksonville | W80-70 | 7-9 | .438 | - | | Alico Arena · Fort Myers, FL |
| 17 | Sat Jan 6 | vsNorth Florida | L58-78 | 7-10 | .412 | - | | Alico Arena · Fort Myers, FL |
| 18 | Wed Jan 10 | atQueens | L75-78 | 7-11 | .389 | - | | Curry Arena · Charlotte, NC |
| 19 | Fri Jan 12 | atKennesaw St | L75-78 | 7-12 | .368 | - | | KSU Convocation Center · Kennesaw, GA |
| 20 | Sat Jan 20 | vsStetson | W80-56 | 8-12 | .400 | - | | Alico Arena · Fort Myers, FL |
| 21 | Thu Jan 25 | vsLipscomb | L72-98 | 8-13 | .381 | - | | Alico Arena · Fort Myers, FL |
| 22 | Sat Jan 27 | vsAustin Peay | W73-67 | 9-13 | .409 | - | | Alico Arena · Fort Myers, FL |
| 23 | Thu Feb 1 | atC Arkansas | W82-59 | 10-13 | .435 | - | | Farris Center · Conway, AR |
| 24 | Sat Feb 3 | atNorth Alabama | L69-70 | 10-14 | .417 | - | | Flowers Hall · Florence, AL |
| 25 | Wed Feb 7 | atE Kentucky | L82-90 | 10-15 | .400 | - | ESPNU | McBrayer Arena · Richmond, KY |
| 26 | Sat Feb 10 | vsBellarmine | W63-52 | 11-15 | .423 | - | | Alico Arena · Fort Myers, FL |
| 27 | Sat Feb 17 | atStetson | L60-61 | 11-16 | .407 | - | | Edmunds Center · Deland, FL |
| 28 | Thu Feb 22 | vsKennesaw St | L67-74 | 11-17 | .393 | - | | Alico Arena · Fort Myers, FL |
| 29 | Sat Feb 24 | vsQueens | W90-81 | 12-17 | .414 | - | | Alico Arena · Fort Myers, FL |
| 30 | Wed Feb 28 | atNorth Florida | W79-60 | 13-17 | .433 | - | | UNF Arena · Jacksonville, FL |
| 31 | Fri Mar 1 | atJacksonville | W59-57 | 14-17 | .452 | - | | Swisher Gymnasium · Jacksonville, FL |
| 32 | Mon Mar 4 | vsQueens | L63-69 | 14-18 | .438 | - | | Alico Arena · Fort Myers, FL |
