| 1 | Tue Nov 5 | vs Wagner | W105-71 | 1-0 | 1.000 | #12 | FS1 | Prudential Center · Newark, NJ |
| 2 | Sat Nov 9 | vsStony Brook | W74-57 | 2-0 | 1.000 | #12 | | Prudential Center · Newark, NJ |
| 3 | Thu Nov 14 | vsMichigan St | L73-76 | 2-1 | .667 | - | FS1 | Prudential Center · Newark, NJ |
| 4 | Sun Nov 17 | atSaint Louis | W83-66 | 3-1 | .750 | #12 | ESPNU | Chaifetz Arena · St. Louis, MO |
| 5 | Sat Nov 23 | vsFAMU | W87-51 | 4-1 | .800 | #13 | FS2 | Prudential Center · Newark, NJ |
| 6 | Wed Nov 27 | vsOregon | L69-71 | 4-2 | .667 | - | ESPN2 | Prudential Center · Newark, NJ |
| 7 | Thu Nov 28 | atSouthern Miss | W81-56 | 5-2 | .714 | - | ESPN2 | Reed Green Coliseum · Hattiesburg, MS |
| 8 | Fri Nov 29 | atIowa State | W84-76 | 6-2 | .750 | - | ESPNU | James H. Hilton Coliseum · Ames, IA |
| 9 | Sun Dec 8 | atIowa State | L66-76 | 6-3 | .667 | #16 | ESPN2 | James H. Hilton Coliseum · Ames, IA |
| 10 | Sat Dec 14 | atRutgers | L48-68 | 6-4 | .600 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 11 | Thu Dec 19 | vs7Maryland | W52-48 | 7-4 | .636 | - | FS1 | Prudential Center · Newark, NJ |
| 12 | Sun Dec 22 | vsPrairie View | W75-55 | 8-4 | .667 | - | FS1 | Prudential Center · Newark, NJ |
| 13 | Mon Dec 30 | atDePaul | W74-66 | 9-4 | .692 | - | FS1 | Wintrust Arena · Chicago, IL |
| 14 | Fri Jan 3 | vsGeorgetown | W78-62 | 10-4 | .714 | - | FS1 | Prudential Center · Newark, NJ |
| 15 | Wed Jan 8 | atXavier | W83-71 | 11-4 | .733 | - | FS1 | Cintas Center · Cincinnati, OH |
| 16 | Sat Jan 11 | vsMarquette | W69-55 | 12-4 | .750 | - | CBSSN | Prudential Center · Newark, NJ |
| 17 | Wed Jan 15 | at5Butler | W78-70 | 13-4 | .765 | #18 | FS1 | Hinkle Fieldhouse · Indianapolis, IN |
| 18 | Sat Jan 18 | atSt John's | W82-79 | 14-4 | .778 | #18 | FOX | Carnesecca Arena · Queens, NY |
| 19 | Wed Jan 22 | vsProvidence | W73-64 | 15-4 | .789 | #10 | FS1 | Prudential Center · Newark, NJ |
| 20 | Wed Jan 29 | vsDePaul | W64-57 | 16-4 | .800 | #10 | FS1 | Prudential Center · Newark, NJ |
| 21 | Sat Feb 1 | vsXavier | L62-74 | 16-5 | .762 | #10 | FOX | Prudential Center · Newark, NJ |
| 22 | Wed Feb 5 | atGeorgetown | W78-71 | 17-5 | .773 | #12 | FS1 | Capital One Arena · Washington, D.C. |
| 23 | Sat Feb 8 | at10Villanova | W70-64 | 18-5 | .783 | #12 | FOX | Xfinity Mobile Arena · Philadelphia, PA |
| 24 | Wed Feb 12 | vs23Creighton | L82-87 | 18-6 | .750 | #10 | FS1 | Prudential Center · Newark, NJ |
| 25 | Sat Feb 15 | atProvidence | L71-74 | 18-7 | .720 | #10 | CBSSN | Amica Mutual Pavilion · Providence, RI |
| 26 | Wed Feb 19 | vs21Butler | W74-72 | 19-7 | .731 | #16 | FS1 | Prudential Center · Newark, NJ |
| 27 | Sun Feb 23 | vsSt John's | W81-65 | 20-7 | .741 | #16 | CBS | Prudential Center · Newark, NJ |
| 28 | Sat Feb 29 | atMarquette | W88-79 | 21-7 | .750 | #13 | FOX | Fiserv Forum · Milwaukee, WI |
| 29 | Wed Mar 4 | vs14Villanova | L77-79 | 21-8 | .724 | #8 | FS1 | Prudential Center · Newark, NJ |
| 30 | Sat Mar 7 | at11Creighton | L60-77 | 21-9 | .700 | #8 | FOX | CHI Health Center Omaha · Omaha, NE |
