| 1 | Wed Nov 10 | vs Fairleigh | W93-49 | -27 | 1-0 | 1.000 | - | FS1 | Prudential Center · Newark, NJ |
| 2 | Sun Nov 14 | vsYale | W80-44 | -11½ | 2-0 | 1.000 | - | FS1 | Prudential Center · Newark, NJ |
| 3 | Tue Nov 16 | atMichigan | W67-65 | +8 | 3-0 | 1.000 | - | FS1 | Crisler Center · Ann Arbor, MI |
| 4 | Mon Nov 22 | atOhio State | L76-79 | +2½ | 3-1 | .750 | - | FS1 | Value City Arena · Columbus, OH |
| 5 | Wed Nov 24 | atCalifornia | W62-59 | -12 | 4-1 | .800 | - | | Haas Pavilion · Berkeley, CA |
| 6 | Sun Nov 28 | vsBethune | W84-70 | -31½ | 5-1 | .833 | #21 | FS1 | Prudential Center · Newark, NJ |
| 7 | Wed Dec 1 | vsWagner | W85-63 | -18 | 6-1 | .857 | #25 | FS2 | Prudential Center · Newark, NJ |
| 8 | Sat Dec 4 | vsTBD | W113-67 | - | 7-1 | .875 | #25 | FS2 | Prudential Center · Newark, NJ |
| 9 | Thu Dec 9 | vsTexas | W64-60 | -1½ | 8-1 | .889 | - | FS1 | Prudential Center · Newark, NJ |
| 10 | Sun Dec 12 | vsRutgers | W77-63 | -8 | 9-1 | .900 | - | FS1 | Prudential Center · Newark, NJ |
| 12 | Mon Dec 20 | vsSt John's | PPD | - | 9-1 | .900 | #15 | | Prudential Center · Newark, NJ |
| 13 | Thu Dec 23 | atDePaul | PPD | - | 9-1 | .900 | #15 | | Wintrust Arena · Chicago, IL |
| 14 | Wed Dec 29 | at21Providence | L65-70 | +2½ | 9-2 | .818 | #15 | FS1 | Amica Mutual Pavilion · Providence, RI |
| 15 | Sat Jan 1 | vs22Villanova | L67-73 | +2 | 9-3 | .750 | #15 | | Prudential Center · Newark, NJ |
| 16 | Tue Jan 4 | atButler | W71-56 | -3½ | 10-3 | .769 | #24 | CBS Sports Network | Hinkle Fieldhouse · Indianapolis, IN |
| 17 | Sat Jan 8 | vsUConn | W90-87 (OT) | -4½ | 11-3 | .786 | #24 | FOX | Prudential Center · Newark, NJ |
| 18 | Thu Jan 13 | atDePaul | L92-96 | -6½ | 11-4 | .733 | #20 | FS1 | Wintrust Arena · Chicago, IL |
| 19 | Sat Jan 15 | atMarquette | L72-73 | -1½ | 11-5 | .688 | #20 | FS1 | Fiserv Forum · Milwaukee, WI |
| 21 | Sat Jan 22 | atSt John's | W66-60 | -1 | 12-5 | .706 | - | FS1 | Carnesecca Arena · Queens, NY |
| 22 | Mon Jan 24 | vsSt John's | L63-84 | -6½ | 12-6 | .667 | - | FS1 | Prudential Center · Newark, NJ |
| 23 | Wed Jan 26 | vs22Marquette | L63-73 | -6 | 12-7 | .632 | - | FS1 | Prudential Center · Newark, NJ |
| 24 | Tue Feb 1 | atGeorgetown | W70-63 | -7½ | 13-7 | .650 | - | FS1 | Capital One Arena · Washington, D.C. |
| 25 | Fri Feb 4 | vsCreighton | W74-55 | -5 | 14-7 | .667 | - | FS1 | Prudential Center · Newark, NJ |
| 26 | Wed Feb 9 | vs25Xavier | W73-71 | -3 | 15-7 | .682 | - | FS1 | Prudential Center · Newark, NJ |
| 27 | Sat Feb 12 | at15Villanova | L67-73 | +9 | 15-8 | .652 | - | FOX | Xfinity Mobile Arena · Philadelphia, PA |
| 28 | Wed Feb 16 | at24UConn | L65-70 | +5½ | 15-9 | .625 | - | CBS Sports Network | Gampel Pavilion · Storrs, CT |
| 29 | Sat Feb 19 | vsDePaul | W66-64 | -8 | 16-9 | .640 | - | | Prudential Center · Newark, NJ |
| 30 | Wed Feb 23 | vsButler | W66-60 | -8½ | 17-9 | .654 | - | FS1 | Prudential Center · Newark, NJ |
| 31 | Sat Feb 26 | atXavier | W82-66 | +4½ | 18-9 | .667 | - | FOX | Cintas Center · Cincinnati, OH |
| 32 | Wed Mar 2 | vsGeorgetown | W73-68 | -13 | 19-9 | .679 | - | CBS Sports Network | Prudential Center · Newark, NJ |
| 33 | Sat Mar 5 | atCreighton | W65-60 | +2 | 20-9 | .690 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 34 | Wed Mar 9 | vsGeorgetown | W57-53 | -9½ | 21-9 | .700 | - | FS1 | Prudential Center · Newark, NJ |
| 35 | Thu Mar 10 | atUConn | L52-62 | +4½ | 21-10 | .677 | - | FS1 | Gampel Pavilion · Storrs, CT |
| 34 | Fri Mar 18 | vs9TCU | L42-69 | -1½ | 21-11 | .656 | #8 | truTV | Viejas Arena · San Diego, CA |
