| 1 | Sat Nov 28 | at Jacksonville | L51-66 | 0-1 | .000 | - | | Swisher Gymnasium · Jacksonville, FL |
| 3 | Wed Dec 2 | vsTBD | W80-53 | 1-1 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 5 | Wed Dec 9 | atTulane | L38-58 | 1-2 | .333 | - | | Devlin Fieldhouse · New Orleans, LA |
| 6 | Sat Dec 12 | vsSouth Alabama | L75-76 | 1-3 | .250 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 7 | Tue Dec 15 | atLamar | W66-63 | 2-3 | .400 | - | | Montagne Center · Beaumont, TX |
| 8 | Sat Dec 19 | vsUL Monroe | W60-47 | 3-3 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 9 | Mon Dec 28 | vsTBD | W74-54 | 4-3 | .571 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 10 | Fri Jan 1 | vsUTEP | W74-66 (OT) | 5-3 | .625 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 11 | Sat Jan 2 | vsUTEP | L62-77 | 5-4 | .556 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 12 | Fri Jan 8 | atUAB | L60-72 | 5-5 | .500 | - | | Bartow Arena · Birmingham, AL |
| 13 | Sat Jan 9 | atUAB | L58-62 | 5-6 | .455 | - | | Bartow Arena · Birmingham, AL |
| 14 | Fri Jan 15 | vsMTSU | W84-54 | 6-6 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 15 | Sat Jan 16 | vsMTSU | W64-59 | 7-6 | .538 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 16 | Fri Jan 22 | atUTSA | L64-70 | 7-7 | .500 | - | | UTSA Convocation Center · San Antonio, TX |
| 17 | Sat Jan 23 | atUTSA | L72-78 | 7-8 | .467 | - | | UTSA Convocation Center · San Antonio, TX |
| 18 | Thu Jan 28 | vsLouisiana Tech | L63-76 | 7-9 | .438 | - | CBS | Reed Green Coliseum · Hattiesburg, MS |
| 19 | Sat Jan 30 | atLouisiana Tech | L62-65 | 7-10 | .412 | - | | Thomas Assembly Center · Ruston, LA |
| 20 | Fri Feb 5 | atRice | L62-88 | 7-11 | .389 | - | | Tudor Fieldhouse · Houston, TX |
| 21 | Sat Feb 6 | atRice | L68-76 | 7-12 | .368 | - | | Tudor Fieldhouse · Houston, TX |
| 22 | Fri Feb 12 | vsNorth Texas | L49-65 | 7-13 | .350 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 23 | Sat Feb 13 | vsNorth Texas | L56-68 | 7-14 | .333 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 24 | Fri Feb 19 | atFIU | W85-72 | 8-14 | .364 | - | | Ocean Bank Convocation Center · Miami, FL |
| 25 | Sat Feb 20 | atFIU | PPD | 8-17 | .320 | - | | Ocean Bank Convocation Center · Miami, FL |
| 26 | Fri Feb 26 | vsFAU | L60-69 | 8-15 | .348 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 27 | Sat Feb 27 | vsFAU | L66-73 | 8-16 | .333 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 28 | Tue Mar 9 | atRice | L52-61 | 8-17 | .320 | - | | Tudor Fieldhouse · Houston, TX |
