| 1 | Mon Nov 6 | vs TBD | W64-42 | 1-0 | 1.000 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 2 | Fri Nov 10 | at Akron | L54-72 | 1-1 | .500 | - | | James A. Rhodes Arena · Akron, OH |
| 3 | Wed Nov 15 | vsTBD | W76-45 | 2-1 | .667 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 4 | Sun Nov 19 | at Utah Valley | L65-67 | 2-2 | .500 | - | | UCCU Center · Orem, UT |
| 5 | Mon Nov 20 | vs Fullerton | L67-74 | 2-3 | .400 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 6 | Wed Nov 22 | vs S Dakota St | L54-65 | 2-4 | .333 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 7 | Sat Nov 25 | at Milwaukee | W90-84 | 3-4 | .429 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 8 | Fri Dec 1 | at UAB | W85-82 | 4-4 | .500 | - | | Bartow Arena · Birmingham, AL |
| 9 | Sat Dec 9 | vs N'Western St | W83-74 | 5-4 | .556 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 10 | Wed Dec 13 | at McNeese | L48-67 | 5-5 | .500 | - | | Legacy Center · Lake Charles, LA |
| 11 | Mon Dec 18 | at Lamar | W82-79 | 6-5 | .545 | - | | Montagne Center · Beaumont, TX |
| 12 | Sat Dec 23 | at #25Ole Miss | L72-89 | 6-6 | .500 | - | | SJB Pavilion · Oxford, MS |
| 13 | Sat Dec 30 | at Georgia So | L67-88 | 6-7 | .462 | - | | W.S. Hanner Fieldhouse · Statesboro, GA |
| 14 | Thu Jan 4 | vs Georgia St | W79-73 | 7-7 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 15 | Sat Jan 6 | vs #19JMU | W81-71 | 8-7 | .533 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 16 | Thu Jan 11 | at UL Monroe | W71-58 | 9-7 | .563 | - | | Fant-Ewing Coliseum · Monroe, LA |
| 17 | Sat Jan 13 | at Troy | L56-82 | 9-8 | .529 | - | | Trojan Arena · Troy, AL |
| 18 | Wed Jan 17 | vs Arkansas St | W69-66 | 10-8 | .556 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 19 | Sat Jan 20 | vsTroy | W64-63 | 11-8 | .579 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 20 | Wed Jan 24 | at Coast Car | W79-63 | 12-8 | .600 | - | | The HTC Center · Conway, SC |
| 21 | Sat Jan 27 | at Marshall | L67-83 | 12-9 | .571 | - | | Cam Henderson Center · Huntington, WV |
| 22 | Wed Jan 31 | atArkansas St | L71-78 | 12-10 | .545 | - | | First National Bank Arena · Jonesboro, AR |
| 23 | Sat Feb 3 | at Texas St | L55-60 | 12-11 | .522 | - | | Strahan Arena at the University Events Center · San Marcos, TX |
| 24 | Wed Feb 7 | vs Old Dominion | W78-73 | 13-11 | .542 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 25 | Sat Feb 10 | vs W Michigan | W86-54 | 14-11 | .560 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 26 | Thu Feb 15 | vsUL Monroe | L59-68 | 14-12 | .538 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 27 | Sat Feb 17 | vsTexas St | W78-74 | 15-12 | .556 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 28 | Thu Feb 22 | vs South Alabama | L64-83 | 15-13 | .536 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 29 | Sat Feb 24 | vs Louisiana | W82-71 | 16-13 | .552 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 30 | Wed Feb 28 | atSouth Alabama | L70-73 | 16-14 | .533 | - | | Mitchell Center · Mobile, AL |
| 31 | Fri Mar 1 | atLouisiana | L61-77 | 16-15 | .516 | - | | Cajundome · Lafayette, LA |
| 32 | Thu Mar 7 | vsTexas St | L59-75 | 16-16 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
