| 2 | Mon Nov 30 | at Alabama | W82-64 | 1-0 | 1.000 | - | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 3 | Tue Dec 1 | vsUNC | L63-67 | 1-1 | .500 | - | ESPN | Maples Pavilion · Stanford, CA |
| 4 | Wed Dec 2 | vsIndiana | L63-79 | 1-2 | .333 | - | ESPN | Maples Pavilion · Stanford, CA |
| 5 | Sun Dec 6 | atNC A&T | W78-46 | 2-2 | .500 | - | | Corbett Sports Center · Greensboro, NC |
| 7 | Sun Dec 13 | atUSC | PPD | 14-13 | .519 | - | FS1 | Galen Center · Los Angeles, CA |
| 8 | Tue Dec 15 | atCSU Northridge | W82-71 | 3-2 | .600 | - | | Premier America Credit Union Arena · Northridge, CA |
| 9 | Sat Dec 19 | vsArizona | W78-75 | 4-2 | .667 | - | PACN | Maples Pavilion · Stanford, CA |
| 10 | Mon Dec 21 | vsBakersfield | W63-50 | 5-2 | .714 | - | | Maples Pavilion · Stanford, CA |
| 11 | Sat Jan 2 | at21Oregon | L56-73 | 5-3 | .625 | - | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 12 | Mon Jan 4 | atOregon St | W81-71 | 6-3 | .667 | - | PACN | Gill Coliseum · Corvallis, OR |
| 13 | Thu Jan 7 | vsWashington | W91-75 | 7-3 | .700 | - | FS1 | Maples Pavilion · Stanford, CA |
| 14 | Sat Jan 9 | vsWashington St | W75-60 | 8-3 | .727 | - | PACN | Maples Pavilion · Stanford, CA |
| 15 | Thu Jan 14 | atUtah | L65-79 | 8-4 | .667 | - | ESPN2 | Jon M. Huntsman Center · Salt Lake City, UT |
| 16 | Sat Jan 16 | atColorado | L64-77 | 8-5 | .615 | - | PACN | CU Events Center · Boulder, CO |
| 17 | Thu Jan 21 | vsUSC | PPD | 14-13 | .519 | - | FS1 | Maples Pavilion · Stanford, CA |
| 18 | Sat Jan 23 | vs24UCLA | W73-72 (OT) | 9-5 | .643 | - | FOX | Maples Pavilion · Stanford, CA |
| 19 | Thu Jan 28 | atArizona | W73-64 | 10-5 | .667 | - | ESPN2 | McKale Center · Tucson, AZ |
| 20 | Sat Jan 30 | atArizona St | L75-79 | 10-6 | .625 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 21 | Tue Feb 2 | vsUSC | L66-72 | 10-7 | .588 | - | FS1 | Maples Pavilion · Stanford, CA |
| 22 | Thu Feb 4 | atCalifornia | W70-55 | 11-7 | .611 | - | ESPN2 | Haas Pavilion · Berkeley, CA |
| 23 | Sun Feb 7 | vsCalifornia | W76-70 | 12-7 | .632 | - | FS1 | Maples Pavilion · Stanford, CA |
| 24 | Thu Feb 11 | vsColorado | L51-69 | 12-8 | .600 | - | ESPN2 | Maples Pavilion · Stanford, CA |
| 25 | Sat Feb 13 | vsUtah | W73-66 | 13-8 | .619 | - | PACN | Maples Pavilion · Stanford, CA |
| 26 | Thu Feb 18 | atWashington | W79-61 | 14-8 | .636 | - | FS1 | Alaska Airlines Arena · Seattle, WA |
| 27 | Sat Feb 20 | atWashington St | L76-85 (3OT) | 14-9 | .609 | - | ESPN2 | Friel Court at Beasley Coliseum · Pullman, WA |
| 28 | Thu Feb 25 | vsOregon | L68-71 | 14-10 | .583 | - | ESPNU | Maples Pavilion · Stanford, CA |
| 29 | Sat Feb 27 | vsOregon St | L62-73 | 14-11 | .560 | - | PACN | Maples Pavilion · Stanford, CA |
| 30 | Wed Mar 3 | atUSC | L42-79 | 14-12 | .538 | - | | Galen Center · Los Angeles, CA |
| 31 | Wed Mar 10 | vsCalifornia | L58-76 | 14-13 | .519 | - | PACN | T-Mobile Arena · Las Vegas, NV |
