| 1 | Tue Nov 4 | vs Portland St | W89-79 | 1-0 | 1.000 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 2 | Sat Nov 8 | vsMontana | W91-68 | 2-0 | 1.000 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 3 | Wed Nov 12 | vsMontana St | W77-68 | 3-0 | 1.000 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 4 | Tue Nov 18 | vsLouisiana | W93-66 | 4-0 | 1.000 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 5 | Fri Nov 21 | vsSeattle U | L69-77 | 4-1 | .800 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 6 | Thu Nov 27 | atMinnesota | W72-68 | 5-1 | .833 | - | CBSSN | Williams Arena · Minneapolis, MN |
| 7 | Fri Nov 28 | atSaint Louis | W78-77 | 6-1 | .857 | - | truTV | Chaifetz Arena · St. Louis, MO |
| 8 | Mon Dec 1 | vsPortland | W94-72 | 7-1 | .875 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 9 | Sun Dec 7 | vsUNLV | L74-75 | 7-2 | .778 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 10 | Sat Dec 13 | atSan Jose St | W86-82 | 8-2 | .800 | - | CBSSN | Provident Credit Union Event Center · San Jose, CA |
| 11 | Wed Dec 17 | vsUT Arlington | W76-60 | 9-2 | .818 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 12 | Sat Dec 20 | atColorado | W77-68 | 10-2 | .833 | - | ESPNU | Mortgage Matchup Center · Phoenix, AZ |
| 13 | Sat Dec 27 | vsCSU Northridge | W88-80 | 11-2 | .846 | - | ACC Extra | Maples Pavilion · Stanford, CA |
| 14 | Tue Dec 30 | vsNotre Dame | L40-47 | 11-3 | .786 | - | ESPN2 | Maples Pavilion · Stanford, CA |
| 15 | Fri Jan 2 | vs16Louisville | W80-76 | 12-3 | .800 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 16 | Wed Jan 7 | atVirginia Tech | W69-68 | 13-3 | .813 | - | ACC Network | Cassell Coliseum · Blacksburg, VA |
| 17 | Sat Jan 10 | at23Virginia | L55-70 | 13-4 | .765 | - | The CW Network | John Paul Jones Arena · Charlottesville, VA |
| 18 | Wed Jan 14 | vs14UNC | W95-90 | 14-4 | .778 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 19 | Sat Jan 17 | vs6Duke | L50-80 | 14-5 | .737 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 20 | Sat Jan 24 | vsCalifornia | L66-78 | 14-6 | .700 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 21 | Wed Jan 28 | atMiami | L70-79 | 14-7 | .667 | - | ACC Network | Watsco Center · Coral Gables, FL |
| 22 | Sat Jan 31 | atFlorida St | L80-88 | 14-8 | .636 | - | ACC Network | Donald L. Tucker Center · Tallahassee, FL |
| 23 | Wed Feb 4 | vs20Clemson | L64-66 | 14-9 | .609 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 24 | Sat Feb 7 | vsGeorgia Tech | W95-72 | 15-9 | .625 | - | ESPNU | Maples Pavilion · Stanford, CA |
| 25 | Wed Feb 11 | atBoston College | W70-64 | 16-9 | .640 | - | ESPNU | Silvio O. Conte Forum · Chestnut Hill, MA |
| 26 | Sat Feb 14 | atWake Forest | L63-68 | 16-10 | .615 | - | ACC Network | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
| 27 | Sat Feb 21 | atCalifornia | L66-72 | 16-11 | .593 | - | ACC Network | Haas Pavilion · Berkeley, CA |
| 28 | Wed Feb 25 | vsPitt | W75-67 | 17-11 | .607 | - | ACC Network | Maples Pavilion · Stanford, CA |
| 29 | Sat Feb 28 | vsSMU | W95-75 | 18-11 | .621 | - | ACC Network | Maples Pavilion · Stanford, CA |
