| 1 | Thu Oct 14 | vs Islanders | W6-3 | 1-0-0 | 2 PTS | PNC Arena · Raleigh, NC |
| 2 | Sat Oct 16 | atPredators | W3-2 | 2-0-0 | 4 PTS | Bridgestone Arena · Nashville, TN |
| 3 | Thu Oct 21 | atCanadiens | W4-1 | 3-0-0 | 6 PTS | Bell Centre · Montreal, QC |
| 4 | Sat Oct 23 | atJackets | W5-1 | 4-0-0 | 8 PTS | Nationwide Arena · Columbus, OH |
| 5 | Mon Oct 25 | vsMaple Leafs | W4-1 | 5-0-0 | 10 PTS | PNC Arena · Raleigh, NC |
| 6 | Thu Oct 28 | vsBruins | W3-0 | 6-0-0 | 12 PTS | PNC Arena · Raleigh, NC |
| 7 | Fri Oct 29 | vsBlackhawks | W6-3 | 7-0-0 | 14 PTS | PNC Arena · Raleigh, NC |
| 8 | Sun Oct 31 | vsCoyotes | W2-1 | 8-0-0 | 16 PTS | PNC Arena · Raleigh, NC |
| 9 | Wed Nov 3 | atBlackhawks | W4-3 | 9-0-0 | 18 PTS | United Center · Chicago, IL |
| 10 | Sat Nov 6 | atPanthers | L2-5 | 9-1-0 | 18 PTS | Amerant Bank Arena · Sunrise, FL |
| 11 | Tue Nov 9 | atLightning | W2-1 (OT) | 10-1-0 | 20 PTS | AMALIE Arena · Tampa, FL |
| 12 | Fri Nov 12 | vsFlyers | L1-2 | 10-2-0 | 20 PTS | PNC Arena · Raleigh, NC |
| 13 | Sat Nov 13 | vsBlues | W3-2 | 11-2-0 | 22 PTS | PNC Arena · Raleigh, NC |
| 14 | Tue Nov 16 | atKnights | W4-2 | 12-2-0 | 24 PTS | T-Mobile Arena · Las Vegas, NV |
| 15 | Thu Nov 18 | atDucks | W2-1 | 13-2-0 | 26 PTS | Honda Center · Anaheim, CA |
| 16 | Sat Nov 20 | atKings | W5-4 | 14-2-0 | 28 PTS | Crypto.com Arena · Los Angeles, CA |
| 17 | Mon Nov 22 | atSharks | L1-2 (OT) | 14-2-1 | 29 PTS | SAP Center · San Jose, CA |
| 18 | Wed Nov 24 | atKraken | L1-2 | 14-3-1 | 29 PTS | Climate Pledge Arena · Seattle, WA |
| 19 | Fri Nov 26 | atFlyers | W6-3 | 15-3-1 | 31 PTS | Wells Fargo Center · Philadelphia, PA |
| 20 | Sun Nov 28 | vsCapitals | L2-4 | 15-4-1 | 31 PTS | PNC Arena · Raleigh, NC |
| 21 | Tue Nov 30 | atStars | L1-4 | 15-5-1 | 31 PTS | American Airlines Center · Dallas, TX |
| 22 | Thu Dec 2 | vsSenators | L2-3 | 15-6-1 | 31 PTS | PNC Arena · Raleigh, NC |
| 23 | Sat Dec 4 | vsSabres | W6-2 | 16-6-1 | 33 PTS | PNC Arena · Raleigh, NC |
| 24 | Tue Dec 7 | atJets | W4-2 | 17-6-1 | 35 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 25 | Thu Dec 9 | atFlames | W2-1 (OT) | 18-6-1 | 37 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 26 | Sat Dec 11 | atOilers | W3-1 | 19-6-1 | 39 PTS | Rogers Place · Edmonton, AB |
| 27 | Sun Dec 12 | atCanucks | L1-2 | 19-7-1 | 39 PTS | Rogers Arena · Vancouver, British Columbia |
| 28 | Thu Dec 16 | vsRed Wings | W5-3 | 20-7-1 | 41 PTS | PNC Arena · Raleigh, NC |
| 29 | Sat Dec 18 | vsKings | W5-1 | 21-7-1 | 43 PTS | PNC Arena · Raleigh, NC |
| 30 | Thu Dec 30 | vsCanadiens | W4-0 | 22-7-1 | 45 PTS | PNC Arena · Raleigh, NC |
| 31 | Sat Jan 1 | atJackets | W7-4 | 23-7-1 | 47 PTS | Nationwide Arena · Columbus, OH |
| 32 | Fri Jan 7 | vsFlames | W6-3 | 24-7-1 | 49 PTS | PNC Arena · Raleigh, NC |
| 33 | Sat Jan 8 | vsPanthers | L3-4 (OT) | 24-7-2 | 50 PTS | PNC Arena · Raleigh, NC |
| 34 | Thu Jan 13 | vsJackets | L0-6 | 24-8-2 | 50 PTS | PNC Arena · Raleigh, NC |
| 35 | Sat Jan 15 | vsCanucks | W4-1 | 25-8-2 | 52 PTS | PNC Arena · Raleigh, NC |
| 36 | Tue Jan 18 | atBruins | W7-1 | 26-8-2 | 54 PTS | TD Garden · Boston, MA |
| 37 | Fri Jan 21 | vsRangers | W6-3 | 27-8-2 | 56 PTS | PNC Arena · Raleigh, NC |
| 38 | Sat Jan 22 | atDevils | L4-7 | 27-9-2 | 56 PTS | Prudential Center · Newark, NJ |
| 39 | Tue Jan 25 | vsKnights | W4-3 (OT) | 28-9-2 | 58 PTS | PNC Arena · Raleigh, NC |
| 40 | Thu Jan 27 | atSenators | W3-2 (SO) | 29-9-2 | 60 PTS | Canadian Tire Centre · Ottawa, ON |
| 41 | Sat Jan 29 | vsDevils | W2-1 | 30-9-2 | 62 PTS | PNC Arena · Raleigh, NC |
| 42 | Sun Jan 30 | vsSharks | W2-1 | 31-9-2 | 64 PTS | PNC Arena · Raleigh, NC |
| 43 | Mon Feb 7 | atMaple Leafs | L3-4 (OT) | 31-9-3 | 65 PTS | Scotiabank Arena · Toronto, ON |
| 44 | Tue Feb 8 | atSenators | L3-4 | 31-10-3 | 65 PTS | Canadian Tire Centre · Ottawa, ON |
| 45 | Thu Feb 10 | atBruins | W6-0 | 32-10-3 | 67 PTS | TD Garden · Boston, MA |
| 46 | Sat Feb 12 | atWild | L2-3 | 32-11-3 | 67 PTS | Xcel Energy Center · St. Paul, MN |
| 47 | Wed Feb 16 | vsPanthers | L2-3 (OT) | 32-11-4 | 68 PTS | PNC Arena · Raleigh, NC |
| 48 | Fri Feb 18 | vsPredators | W5-3 | 33-11-4 | 70 PTS | PNC Arena · Raleigh, NC |
| 49 | Sun Feb 20 | atPenguins | W4-3 | 34-11-4 | 72 PTS | PPG Paints Arena · Pittsburgh, PA |
| 50 | Mon Feb 21 | atFlyers | W4-3 (OT) | 35-11-4 | 74 PTS | Wells Fargo Center · Philadelphia, PA |
| 51 | Fri Feb 25 | vsJackets | W4-0 | 36-11-4 | 76 PTS | PNC Arena · Raleigh, NC |
| 52 | Sun Feb 27 | vsOilers | W2-1 | 37-11-4 | 78 PTS | PNC Arena · Raleigh, NC |
| 53 | Tue Mar 1 | atRed Wings | L3-4 (OT) | 37-11-5 | 79 PTS | Little Caesars Arena · Detroit, MI |
| 54 | Thu Mar 3 | atCapitals | L0-4 | 37-12-5 | 79 PTS | Capital One Arena · Washington, D.C. |
| 55 | Fri Mar 4 | vsPenguins | W3-2 (OT) | 38-12-5 | 81 PTS | PNC Arena · Raleigh, NC |
| 56 | Sun Mar 6 | vsKraken | W3-2 | 39-12-5 | 83 PTS | PNC Arena · Raleigh, NC |
| 57 | Thu Mar 10 | vsAvalanche | W2-0 | 40-12-5 | 85 PTS | PNC Arena · Raleigh, NC |
| 58 | Sat Mar 12 | vsFlyers | W3-1 | 41-12-5 | 87 PTS | PNC Arena · Raleigh, NC |
| 59 | Sun Mar 13 | atPenguins | L2-4 | 41-13-5 | 87 PTS | PPG Paints Arena · Pittsburgh, PA |
| 60 | Thu Mar 17 | atMaple Leafs | L2-3 | 41-14-5 | 87 PTS | Scotiabank Arena · Toronto, ON |
| 61 | Fri Mar 18 | vsCapitals | L3-4 (SO) | 41-14-6 | 88 PTS | PNC Arena · Raleigh, NC |
| 62 | Sun Mar 20 | vsRangers | L0-2 | 41-15-6 | 88 PTS | PNC Arena · Raleigh, NC |
| 63 | Tue Mar 22 | vsLightning | W3-2 | 42-15-6 | 90 PTS | PNC Arena · Raleigh, NC |
| 64 | Thu Mar 24 | vsStars | L3-4 (SO) | 42-15-7 | 91 PTS | PNC Arena · Raleigh, NC |
| 65 | Sat Mar 26 | atBlues | W7-2 | 43-15-7 | 93 PTS | Enterprise Center · St. Louis, MO |
| 66 | Mon Mar 28 | atCapitals | W6-1 | 44-15-7 | 95 PTS | Capital One Arena · Washington, D.C. |
| 67 | Tue Mar 29 | atLightning | L3-4 (OT) | 44-15-8 | 96 PTS | AMALIE Arena · Tampa, FL |
| 68 | Thu Mar 31 | vsCanadiens | W4-0 | 45-15-8 | 98 PTS | PNC Arena · Raleigh, NC |
| 69 | Sat Apr 2 | vsWild | L1-3 | 45-16-8 | 98 PTS | PNC Arena · Raleigh, NC |
| 70 | Tue Apr 5 | atSabres | L2-4 | 45-17-8 | 98 PTS | KeyBank Center · Buffalo, NY |
| 71 | Thu Apr 7 | vsSabres | W5-3 | 46-17-8 | 100 PTS | PNC Arena · Raleigh, NC |
| 72 | Fri Apr 8 | vsIslanders | L1-2 | 46-18-8 | 100 PTS | PNC Arena · Raleigh, NC |
| 73 | Sun Apr 10 | vsDucks | W5-2 | 47-18-8 | 102 PTS | PNC Arena · Raleigh, NC |
| 74 | Tue Apr 12 | atRangers | W4-2 | 48-18-8 | 104 PTS | Madison Square Garden · Manhattan, NY |
| 75 | Thu Apr 14 | vsRed Wings | L0-3 | 48-19-8 | 104 PTS | PNC Arena · Raleigh, NC |
| 76 | Sat Apr 16 | atAvalanche | L4-7 | 48-20-8 | 104 PTS | Ball Arena · Denver, CO |
| 77 | Mon Apr 18 | atCoyotes | W5-3 | 49-20-8 | 106 PTS | Mullett Arena · Tempe, AZ |
| 78 | Thu Apr 21 | vsJets | W4-2 | 50-20-8 | 108 PTS | PNC Arena · Raleigh, NC |
| 79 | Sat Apr 23 | atDevils | W3-2 (OT) | 51-20-8 | 110 PTS | Prudential Center · Newark, NJ |
| 80 | Sun Apr 24 | atIslanders | W5-2 | 52-20-8 | 112 PTS | UBS Arena · Elmont, NY |
| 81 | Tue Apr 26 | atRangers | W4-3 | 53-20-8 | 114 PTS | Madison Square Garden · Manhattan, NY |
| 82 | Thu Apr 28 | vsDevils | W6-3 | 54-20-8 | 116 PTS | PNC Arena · Raleigh, NC |
| 1 | Mon May 2 | vsBruins | W5-1 | 1-0 | 1.000 | PNC Arena · Raleigh, NC |
| 2 | Wed May 4 | vsBruins | W5-2 | 2-0 | 1.000 | PNC Arena · Raleigh, NC |
| 3 | Fri May 6 | atBruins | L2-4 | 2-1 | .667 | TD Garden · Boston, MA |
| 4 | Sun May 8 | atBruins | L2-5 | 2-2 | .500 | TD Garden · Boston, MA |
| 5 | Tue May 10 | vsBruins | W5-1 | 3-2 | .600 | PNC Arena · Raleigh, NC |
| 6 | Thu May 12 | atBruins | L2-5 | 3-3 | .500 | TD Garden · Boston, MA |
| 7 | Sat May 14 | vsBruins | W3-2 | 4-3 | .571 | PNC Arena · Raleigh, NC |
| 1 | Wed May 18 | vsRangers | W2-1 (OT) | 1-0 | 1.000 | PNC Arena · Raleigh, NC |
| 2 | Fri May 20 | vsRangers | W2-0 | 2-0 | 1.000 | PNC Arena · Raleigh, NC |
| 3 | Sun May 22 | atRangers | L1-3 | 2-1 | .667 | Madison Square Garden · Manhattan, NY |
| 4 | Tue May 24 | atRangers | L1-4 | 2-2 | .500 | Madison Square Garden · Manhattan, NY |
| 5 | Thu May 26 | vsRangers | W3-1 | 3-2 | .600 | PNC Arena · Raleigh, NC |
| 6 | Sat May 28 | atRangers | L2-5 | 3-3 | .500 | Madison Square Garden · Manhattan, NY |
| 7 | Mon May 30 | vsRangers | L2-6 | 3-4 | .429 | PNC Arena · Raleigh, NC |
