| 1 | Wed Oct 12 | vs Jackets | W4-1 | 1-0-0 | 2 PTS | PNC Arena · Raleigh, NC |
| 2 | Fri Oct 14 | atSharks | W2-1 | 2-0-0 | 4 PTS | SAP Center · San Jose, CA |
| 3 | Mon Oct 17 | atKraken | W5-1 | 3-0-0 | 6 PTS | Climate Pledge Arena · Seattle, WA |
| 4 | Thu Oct 20 | atOilers | L4-6 | 3-1-0 | 6 PTS | Rogers Place · Edmonton, AB |
| 5 | Sat Oct 22 | atFlames | L2-3 (OT) | 3-1-1 | 7 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 6 | Mon Oct 24 | atCanucks | W3-2 | 4-1-1 | 9 PTS | Rogers Arena · Vancouver, British Columbia |
| 7 | Fri Oct 28 | vsIslanders | L2-6 | 4-2-1 | 9 PTS | PNC Arena · Raleigh, NC |
| 8 | Sat Oct 29 | atFlyers | W4-3 (OT) | 5-2-1 | 11 PTS | Wells Fargo Center · Philadelphia, PA |
| 9 | Mon Oct 31 | vsCapitals | W3-2 (SO) | 6-2-1 | 13 PTS | PNC Arena · Raleigh, NC |
| 10 | Thu Nov 3 | atLightning | W4-3 (SO) | 7-2-1 | 15 PTS | AMALIE Arena · Tampa, FL |
| 11 | Fri Nov 4 | vsSabres | W5-3 | 8-2-1 | 17 PTS | PNC Arena · Raleigh, NC |
| 12 | Sun Nov 6 | vsMaple Leafs | L1-3 | 8-3-1 | 17 PTS | PNC Arena · Raleigh, NC |
| 13 | Wed Nov 9 | atPanthers | L0-3 | 8-4-1 | 17 PTS | Amerant Bank Arena · Sunrise, FL |
| 14 | Thu Nov 10 | vsOilers | W7-2 | 9-4-1 | 19 PTS | PNC Arena · Raleigh, NC |
| 15 | Sat Nov 12 | atAvalanche | L1-4 | 9-5-1 | 19 PTS | Ball Arena · Denver, CO |
| 16 | Mon Nov 14 | atBlackhawks | W3-0 | 10-5-1 | 21 PTS | United Center · Chicago, IL |
| 17 | Thu Nov 17 | vsAvalanche | L2-3 (OT) | 10-5-2 | 22 PTS | PNC Arena · Raleigh, NC |
| 18 | Sat Nov 19 | atWild | L1-2 (OT) | 10-5-3 | 23 PTS | Xcel Energy Center · St. Paul, MN |
| 19 | Mon Nov 21 | atJets | L3-4 (OT) | 10-5-4 | 24 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 20 | Wed Nov 23 | vsCoyotes | L0-4 | 10-6-4 | 24 PTS | PNC Arena · Raleigh, NC |
| 21 | Fri Nov 25 | atBruins | L2-3 (OT) | 10-6-5 | 25 PTS | TD Garden · Boston, MA |
| 22 | Sat Nov 26 | vsFlames | W3-2 | 11-6-5 | 27 PTS | PNC Arena · Raleigh, NC |
| 23 | Tue Nov 29 | atPenguins | W3-2 (OT) | 12-6-5 | 29 PTS | PPG Paints Arena · Pittsburgh, PA |
| 24 | Thu Dec 1 | atBlues | W6-4 | 13-6-5 | 31 PTS | Enterprise Center · St. Louis, MO |
| 25 | Sat Dec 3 | atKings | W4-2 | 14-6-5 | 33 PTS | Crypto.com Arena · Los Angeles, CA |
| 26 | Tue Dec 6 | atDucks | L3-4 (OT) | 14-6-6 | 34 PTS | Honda Center · Anaheim, CA |
| 27 | Sat Dec 10 | atIslanders | W3-0 | 15-6-6 | 36 PTS | UBS Arena · Elmont, NY |
| 28 | Tue Dec 13 | atRed Wings | W1-0 | 16-6-6 | 38 PTS | Little Caesars Arena · Detroit, MI |
| 29 | Thu Dec 15 | vsKraken | W3-2 | 17-6-6 | 40 PTS | PNC Arena · Raleigh, NC |
| 30 | Sat Dec 17 | vsStars | W5-4 (OT) | 18-6-6 | 42 PTS | PNC Arena · Raleigh, NC |
| 31 | Sun Dec 18 | vsPenguins | W3-2 | 19-6-6 | 44 PTS | PNC Arena · Raleigh, NC |
| 32 | Tue Dec 20 | vsDevils | W4-1 | 20-6-6 | 46 PTS | PNC Arena · Raleigh, NC |
| 33 | Thu Dec 22 | atPenguins | W4-3 (OT) | 21-6-6 | 48 PTS | PPG Paints Arena · Pittsburgh, PA |
| 34 | Fri Dec 23 | vsFlyers | W6-5 | 22-6-6 | 50 PTS | PNC Arena · Raleigh, NC |
| 35 | Tue Dec 27 | vsBlackhawks | W3-0 | 23-6-6 | 52 PTS | PNC Arena · Raleigh, NC |
| 36 | Fri Dec 30 | vsPanthers | W4-0 | 24-6-6 | 54 PTS | PNC Arena · Raleigh, NC |
| 37 | Sun Jan 1 | atDevils | W5-4 (SO) | 25-6-6 | 56 PTS | Prudential Center · Newark, NJ |
| 38 | Tue Jan 3 | atRangers | L3-5 | 25-7-6 | 56 PTS | Madison Square Garden · Manhattan, NY |
| 39 | Thu Jan 5 | vsPredators | L3-5 | 25-8-6 | 56 PTS | PNC Arena · Raleigh, NC |
| 40 | Sat Jan 7 | atJackets | L3-4 (SO) | 25-8-7 | 57 PTS | Nationwide Arena · Columbus, OH |
| 41 | Tue Jan 10 | vsDevils | L3-5 | 25-9-7 | 57 PTS | PNC Arena · Raleigh, NC |
| 42 | Thu Jan 12 | atJackets | W6-2 | 26-9-7 | 59 PTS | Nationwide Arena · Columbus, OH |
| 43 | Sat Jan 14 | vsPenguins | W2-1 | 27-9-7 | 61 PTS | PNC Arena · Raleigh, NC |
| 44 | Sun Jan 15 | vsCanucks | L3-4 (SO) | 27-9-8 | 62 PTS | PNC Arena · Raleigh, NC |
| 45 | Thu Jan 19 | vsWild | W5-2 | 28-9-8 | 64 PTS | PNC Arena · Raleigh, NC |
| 46 | Sat Jan 21 | atIslanders | W5-2 | 29-9-8 | 66 PTS | UBS Arena · Elmont, NY |
| 47 | Wed Jan 25 | atStars | W3-2 (OT) | 30-9-8 | 68 PTS | American Airlines Center · Dallas, TX |
| 48 | Fri Jan 27 | vsSharks | W5-4 (OT) | 31-9-8 | 70 PTS | PNC Arena · Raleigh, NC |
| 49 | Sun Jan 29 | vsBruins | W4-1 | 32-9-8 | 72 PTS | PNC Arena · Raleigh, NC |
| 50 | Tue Jan 31 | vsKings | W5-4 (OT) | 33-9-8 | 74 PTS | PNC Arena · Raleigh, NC |
| 51 | Wed Feb 1 | atSabres | W5-1 | 34-9-8 | 76 PTS | KeyBank Center · Buffalo, NY |
| 52 | Sat Feb 11 | vsRangers | L2-6 | 34-10-8 | 76 PTS | PNC Arena · Raleigh, NC |
| 53 | Tue Feb 14 | atCapitals | W3-2 | 35-10-8 | 78 PTS | Capital One Arena · Washington, D.C. |
| 54 | Thu Feb 16 | vsCanadiens | W6-2 | 36-10-8 | 80 PTS | PNC Arena · Raleigh, NC |
| 55 | Sat Feb 18 | vsCapitals | W4-1 | 37-10-8 | 82 PTS | PNC Arena · Raleigh, NC |
| 56 | Tue Feb 21 | vsBlues | W4-1 | 38-10-8 | 84 PTS | PNC Arena · Raleigh, NC |
| 57 | Fri Feb 24 | vsSenators | W4-0 | 39-10-8 | 86 PTS | PNC Arena · Raleigh, NC |
| 58 | Sat Feb 25 | vsDucks | L2-3 | 39-11-8 | 86 PTS | PNC Arena · Raleigh, NC |
| 59 | Wed Mar 1 | atKnights | L2-3 | 39-12-8 | 86 PTS | T-Mobile Arena · Las Vegas, NV |
| 60 | Fri Mar 3 | atCoyotes | W6-1 | 40-12-8 | 88 PTS | Mullett Arena · Tempe, AZ |
| 61 | Sun Mar 5 | vsLightning | W6-0 | 41-12-8 | 90 PTS | PNC Arena · Raleigh, NC |
| 62 | Tue Mar 7 | atCanadiens | W4-3 (SO) | 42-12-8 | 92 PTS | Bell Centre · Montreal, QC |
| 63 | Thu Mar 9 | vsFlyers | W1-0 | 43-12-8 | 94 PTS | PNC Arena · Raleigh, NC |
| 64 | Sat Mar 11 | vsKnights | L0-4 | 43-13-8 | 94 PTS | PNC Arena · Raleigh, NC |
| 65 | Sun Mar 12 | atDevils | L0-3 | 43-14-8 | 94 PTS | Prudential Center · Newark, NJ |
| 66 | Tue Mar 14 | vsJets | W5-3 | 44-14-8 | 96 PTS | PNC Arena · Raleigh, NC |
| 67 | Fri Mar 17 | atMaple Leafs | L2-5 | 44-15-8 | 96 PTS | Scotiabank Arena · Toronto, ON |
| 68 | Sat Mar 18 | atFlyers | W5-4 (OT) | 45-15-8 | 98 PTS | Wells Fargo Center · Philadelphia, PA |
| 69 | Tue Mar 21 | atRangers | W3-2 | 46-15-8 | 100 PTS | Madison Square Garden · Manhattan, NY |
| 70 | Thu Mar 23 | vsRangers | L1-2 | 46-16-8 | 100 PTS | PNC Arena · Raleigh, NC |
| 71 | Sat Mar 25 | vsMaple Leafs | W5-3 | 47-16-8 | 102 PTS | PNC Arena · Raleigh, NC |
| 72 | Sun Mar 26 | vsBruins | L3-4 (SO) | 47-16-9 | 103 PTS | PNC Arena · Raleigh, NC |
| 73 | Tue Mar 28 | vsLightning | L0-4 | 47-17-9 | 103 PTS | PNC Arena · Raleigh, NC |
| 74 | Thu Mar 30 | atRed Wings | L2-3 | 47-18-9 | 103 PTS | Little Caesars Arena · Detroit, MI |
| 75 | Sat Apr 1 | atCanadiens | W3-0 | 48-18-9 | 105 PTS | Bell Centre · Montreal, QC |
| 76 | Sun Apr 2 | vsIslanders | W2-1 | 49-18-9 | 107 PTS | PNC Arena · Raleigh, NC |
| 77 | Tue Apr 4 | vsSenators | W3-2 (OT) | 50-18-9 | 109 PTS | PNC Arena · Raleigh, NC |
| 78 | Thu Apr 6 | atPredators | L0-3 | 50-19-9 | 109 PTS | Bridgestone Arena · Nashville, TN |
| 79 | Sat Apr 8 | atSabres | L3-4 | 50-20-9 | 109 PTS | KeyBank Center · Buffalo, NY |
| 80 | Mon Apr 10 | atSenators | L2-3 | 50-21-9 | 109 PTS | Canadian Tire Centre · Ottawa, ON |
| 81 | Tue Apr 11 | vsRed Wings | W4-1 | 51-21-9 | 111 PTS | PNC Arena · Raleigh, NC |
| 82 | Thu Apr 13 | atPanthers | W6-4 | 52-21-9 | 113 PTS | Amerant Bank Arena · Sunrise, FL |
| 1 | Mon Apr 17 | vsIslanders | W2-1 | 1-0 | 1.000 | PNC Arena · Raleigh, NC |
| 2 | Wed Apr 19 | vsIslanders | W4-3 (OT) | 2-0 | 1.000 | PNC Arena · Raleigh, NC |
| 3 | Fri Apr 21 | atIslanders | L1-5 | 2-1 | .667 | UBS Arena · Elmont, NY |
| 4 | Sun Apr 23 | atIslanders | W5-2 | 3-1 | .750 | UBS Arena · Elmont, NY |
| 5 | Tue Apr 25 | vsIslanders | L2-3 | 3-2 | .600 | PNC Arena · Raleigh, NC |
| 6 | Fri Apr 28 | atIslanders | W2-1 (OT) | 4-2 | .667 | UBS Arena · Elmont, NY |
| 1 | Wed May 3 | vsDevils | W5-1 | 1-0 | 1.000 | PNC Arena · Raleigh, NC |
| 2 | Fri May 5 | vsDevils | W6-1 | 2-0 | 1.000 | PNC Arena · Raleigh, NC |
| 3 | Sun May 7 | atDevils | L4-8 | 2-1 | .667 | Prudential Center · Newark, NJ |
| 4 | Tue May 9 | atDevils | W6-1 | 3-1 | .750 | Prudential Center · Newark, NJ |
| 5 | Thu May 11 | vsDevils | W3-2 (OT) | 4-1 | .800 | PNC Arena · Raleigh, NC |
| 1 | Thu May 18 | vsPanthers | L2-3 (OT) | 0-1 | .000 | PNC Arena · Raleigh, NC |
| 2 | Sat May 20 | vsPanthers | L1-2 (OT) | 0-2 | .000 | PNC Arena · Raleigh, NC |
| 3 | Mon May 22 | atPanthers | L0-1 | 0-3 | .000 | Amerant Bank Arena · Sunrise, FL |
| 4 | Wed May 24 | atPanthers | L3-4 | 0-4 | .000 | Amerant Bank Arena · Sunrise, FL |
