| 1 | Fri Oct 15 | at Ducks | W2-1 | 1-0-0 | 2 PTS | Honda Center · Anaheim, CA |
| 2 | Sat Oct 16 | atKings | W3-2 | 2-0-0 | 4 PTS | Crypto.com Arena · Los Angeles, CA |
| 3 | Tue Oct 19 | vsJets | W6-5 (OT) | 3-0-0 | 6 PTS | Xcel Energy Center · St. Paul, MN |
| 4 | Sat Oct 23 | vsDucks | W4-3 (OT) | 4-0-0 | 8 PTS | Xcel Energy Center · St. Paul, MN |
| 5 | Sun Oct 24 | vsPredators | L2-5 | 4-1-0 | 8 PTS | Xcel Energy Center · St. Paul, MN |
| 6 | Tue Oct 26 | atCanucks | W3-2 | 5-1-0 | 10 PTS | Rogers Arena · Vancouver, British Columbia |
| 7 | Thu Oct 28 | atKraken | L1-4 | 5-2-0 | 10 PTS | Climate Pledge Arena · Seattle, WA |
| 8 | Sat Oct 30 | atAvalanche | L1-4 | 5-3-0 | 10 PTS | Ball Arena · Denver, CO |
| 9 | Tue Nov 2 | vsSenators | W5-4 (OT) | 6-3-0 | 12 PTS | Xcel Energy Center · St. Paul, MN |
| 10 | Sat Nov 6 | atPenguins | W5-4 (SO) | 7-3-0 | 14 PTS | PPG Paints Arena · Pittsburgh, PA |
| 11 | Sun Nov 7 | vsIslanders | W5-2 | 8-3-0 | 16 PTS | Xcel Energy Center · St. Paul, MN |
| 12 | Wed Nov 10 | atCoyotes | W5-2 | 9-3-0 | 18 PTS | Mullett Arena · Tempe, AZ |
| 13 | Thu Nov 11 | atKnights | L2-3 | 9-4-0 | 18 PTS | T-Mobile Arena · Las Vegas, NV |
| 14 | Sat Nov 13 | atKraken | W4-2 | 10-4-0 | 20 PTS | Climate Pledge Arena · Seattle, WA |
| 15 | Tue Nov 16 | vsSharks | L1-4 | 10-5-0 | 20 PTS | Xcel Energy Center · St. Paul, MN |
| 16 | Thu Nov 18 | vsStars | W7-2 | 11-5-0 | 22 PTS | Xcel Energy Center · St. Paul, MN |
| 17 | Sat Nov 20 | atPanthers | L4-5 | 11-6-0 | 22 PTS | Amerant Bank Arena · Sunrise, FL |
| 18 | Sun Nov 21 | atLightning | L4-5 (SO) | 11-6-1 | 23 PTS | AMALIE Arena · Tampa, FL |
| 19 | Wed Nov 24 | atDevils | W3-2 (SO) | 12-6-1 | 25 PTS | Prudential Center · Newark, NJ |
| 20 | Fri Nov 26 | vsJets | W7-1 | 13-6-1 | 27 PTS | Xcel Energy Center · St. Paul, MN |
| 21 | Sun Nov 28 | vsLightning | W4-2 | 14-6-1 | 29 PTS | Xcel Energy Center · St. Paul, MN |
| 22 | Tue Nov 30 | vsCoyotes | W5-2 | 15-6-1 | 31 PTS | Xcel Energy Center · St. Paul, MN |
| 23 | Thu Dec 2 | vsDevils | W5-2 | 16-6-1 | 33 PTS | Xcel Energy Center · St. Paul, MN |
| 24 | Sat Dec 4 | vsMaple Leafs | W4-3 (SO) | 17-6-1 | 35 PTS | Xcel Energy Center · St. Paul, MN |
| 25 | Tue Dec 7 | atOilers | W4-1 | 18-6-1 | 37 PTS | Rogers Place · Edmonton, AB |
| 26 | Thu Dec 9 | atSharks | W5-2 | 19-6-1 | 39 PTS | SAP Center · San Jose, CA |
| 27 | Sat Dec 11 | atKings | L1-2 | 19-7-1 | 39 PTS | Crypto.com Arena · Los Angeles, CA |
| 28 | Sun Dec 12 | atKnights | L4-6 | 19-8-1 | 39 PTS | T-Mobile Arena · Las Vegas, NV |
| 29 | Thu Dec 16 | vsSabres | L2-3 (SO) | 19-8-2 | 40 PTS | Xcel Energy Center · St. Paul, MN |
| 30 | Mon Dec 20 | atStars | L4-7 | 19-9-2 | 40 PTS | American Airlines Center · Dallas, TX |
| 31 | Sat Jan 1 | vsBlues | L4-6 | 19-10-2 | 40 PTS | Xcel Energy Center · St. Paul, MN |
| 32 | Thu Jan 6 | atBruins | W3-2 | 20-10-2 | 42 PTS | TD Garden · Boston, MA |
| 33 | Sat Jan 8 | vsCapitals | W3-2 (SO) | 21-10-2 | 44 PTS | Xcel Energy Center · St. Paul, MN |
| 34 | Fri Jan 14 | vsDucks | W7-3 | 22-10-2 | 46 PTS | Xcel Energy Center · St. Paul, MN |
| 35 | Mon Jan 17 | atAvalanche | L3-4 (SO) | 22-10-3 | 47 PTS | Ball Arena · Denver, CO |
| 36 | Fri Jan 21 | atBlackhawks | W5-1 | 23-10-3 | 49 PTS | United Center · Chicago, IL |
| 37 | Sat Jan 22 | vsBlackhawks | W4-3 (OT) | 24-10-3 | 51 PTS | Xcel Energy Center · St. Paul, MN |
| 38 | Mon Jan 24 | vsCanadiens | W8-2 | 25-10-3 | 53 PTS | Xcel Energy Center · St. Paul, MN |
| 39 | Fri Jan 28 | atRangers | W3-2 | 26-10-3 | 55 PTS | Madison Square Garden · Manhattan, NY |
| 40 | Sun Jan 30 | atIslanders | W4-3 | 27-10-3 | 57 PTS | UBS Arena · Elmont, NY |
| 41 | Wed Feb 2 | atBlackhawks | W5-0 | 28-10-3 | 59 PTS | United Center · Chicago, IL |
| 42 | Tue Feb 8 | atJets | L0-2 | 28-11-3 | 59 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 43 | Sat Feb 12 | vsHurricanes | W3-2 | 29-11-3 | 61 PTS | Xcel Energy Center · St. Paul, MN |
| 44 | Mon Feb 14 | vsRed Wings | W7-4 | 30-11-3 | 63 PTS | Xcel Energy Center · St. Paul, MN |
| 45 | Wed Feb 16 | atJets | L3-6 | 30-12-3 | 63 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 46 | Fri Feb 18 | vsPanthers | L2-6 | 30-13-3 | 63 PTS | Xcel Energy Center · St. Paul, MN |
| 47 | Sun Feb 20 | atOilers | W7-3 | 31-13-3 | 65 PTS | Rogers Place · Edmonton, AB |
| 48 | Tue Feb 22 | atSenators | L3-4 | 31-14-3 | 65 PTS | Canadian Tire Centre · Ottawa, ON |
| 49 | Thu Feb 24 | atMaple Leafs | L1-3 | 31-15-3 | 65 PTS | Scotiabank Arena · Toronto, ON |
| 50 | Sat Feb 26 | atFlames | L3-7 | 31-16-3 | 65 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 51 | Tue Mar 1 | vsFlames | L1-5 | 31-17-3 | 65 PTS | Xcel Energy Center · St. Paul, MN |
| 52 | Thu Mar 3 | atFlyers | W5-4 | 32-17-3 | 67 PTS | Wells Fargo Center · Philadelphia, PA |
| 53 | Fri Mar 4 | atSabres | L4-5 | 32-18-3 | 67 PTS | KeyBank Center · Buffalo, NY |
| 54 | Sun Mar 6 | vsStars | L3-6 | 32-19-3 | 67 PTS | Xcel Energy Center · St. Paul, MN |
| 55 | Tue Mar 8 | vsRangers | W5-2 | 33-19-3 | 69 PTS | Xcel Energy Center · St. Paul, MN |
| 56 | Thu Mar 10 | atRed Wings | W6-5 (SO) | 34-19-3 | 71 PTS | Little Caesars Arena · Detroit, MI |
| 57 | Fri Mar 11 | atJackets | L2-3 (SO) | 34-19-4 | 72 PTS | Nationwide Arena · Columbus, OH |
| 58 | Sun Mar 13 | vsPredators | L2-6 | 34-20-4 | 72 PTS | Xcel Energy Center · St. Paul, MN |
| 59 | Wed Mar 16 | vsBruins | W4-2 | 35-20-4 | 74 PTS | Xcel Energy Center · St. Paul, MN |
| 60 | Sat Mar 19 | vsBlackhawks | W3-1 | 36-20-4 | 76 PTS | Xcel Energy Center · St. Paul, MN |
| 61 | Mon Mar 21 | vsKnights | W3-0 | 37-20-4 | 78 PTS | Xcel Energy Center · St. Paul, MN |
| 62 | Thu Mar 24 | vsCanucks | W3-2 (OT) | 38-20-4 | 80 PTS | Xcel Energy Center · St. Paul, MN |
| 63 | Sat Mar 26 | vsJackets | W3-2 (OT) | 39-20-4 | 82 PTS | Xcel Energy Center · St. Paul, MN |
| 64 | Sun Mar 27 | vsAvalanche | W3-2 (OT) | 40-20-4 | 84 PTS | Xcel Energy Center · St. Paul, MN |
| 65 | Tue Mar 29 | vsFlyers | W4-1 | 41-20-4 | 86 PTS | Xcel Energy Center · St. Paul, MN |
| 66 | Thu Mar 31 | vsPenguins | L3-4 (OT) | 41-20-5 | 87 PTS | Xcel Energy Center · St. Paul, MN |
| 67 | Sat Apr 2 | atHurricanes | W3-1 | 42-20-5 | 89 PTS | PNC Arena · Raleigh, NC |
| 68 | Sun Apr 3 | atCapitals | W5-1 | 43-20-5 | 91 PTS | Capital One Arena · Washington, D.C. |
| 69 | Tue Apr 5 | atPredators | L2-6 | 43-21-5 | 91 PTS | Bridgestone Arena · Nashville, TN |
| 70 | Fri Apr 8 | atBlues | L3-4 (OT) | 43-21-6 | 92 PTS | Enterprise Center · St. Louis, MO |
| 71 | Sun Apr 10 | vsKings | W6-3 | 44-21-6 | 94 PTS | Xcel Energy Center · St. Paul, MN |
| 72 | Tue Apr 12 | vsOilers | W5-1 | 45-21-6 | 96 PTS | Xcel Energy Center · St. Paul, MN |
| 73 | Thu Apr 14 | atStars | W3-2 (OT) | 46-21-6 | 98 PTS | American Airlines Center · Dallas, TX |
| 74 | Sat Apr 16 | atBlues | L5-6 (OT) | 46-21-7 | 99 PTS | Enterprise Center · St. Louis, MO |
| 75 | Sun Apr 17 | vsSharks | W5-4 (OT) | 47-21-7 | 101 PTS | Xcel Energy Center · St. Paul, MN |
| 76 | Tue Apr 19 | atCanadiens | W2-0 | 48-21-7 | 103 PTS | Bell Centre · Montreal, QC |
| 77 | Thu Apr 21 | vsCanucks | W6-3 | 49-21-7 | 105 PTS | Xcel Energy Center · St. Paul, MN |
| 78 | Fri Apr 22 | vsKraken | W6-3 | 50-21-7 | 107 PTS | Xcel Energy Center · St. Paul, MN |
| 79 | Sun Apr 24 | atPredators | W5-4 (OT) | 51-21-7 | 109 PTS | Bridgestone Arena · Nashville, TN |
| 80 | Tue Apr 26 | vsCoyotes | L3-5 | 51-22-7 | 109 PTS | Xcel Energy Center · St. Paul, MN |
| 81 | Thu Apr 28 | vsFlames | W3-2 (OT) | 52-22-7 | 111 PTS | Xcel Energy Center · St. Paul, MN |
| 82 | Fri Apr 29 | vsAvalanche | W4-1 | 53-22-7 | 113 PTS | Xcel Energy Center · St. Paul, MN |
| 1 | Mon May 2 | vsBlues | L0-4 | 0-1 | .000 | Xcel Energy Center · St. Paul, MN |
| 2 | Wed May 4 | vsBlues | W6-2 | 1-1 | .500 | Xcel Energy Center · St. Paul, MN |
| 3 | Fri May 6 | atBlues | W5-1 | 2-1 | .667 | Enterprise Center · St. Louis, MO |
| 4 | Sun May 8 | atBlues | L2-5 | 2-2 | .500 | Enterprise Center · St. Louis, MO |
| 5 | Tue May 10 | vsBlues | L2-5 | 2-3 | .400 | Xcel Energy Center · St. Paul, MN |
| 6 | Thu May 12 | atBlues | L1-5 | 2-4 | .333 | Enterprise Center · St. Louis, MO |
