| 1 | Fri Oct 7 | vs Sharks | W4-1 | 1-0-0 | 2 PTS | O2 Arena · Prague, Czechia |
| 2 | Sat Oct 8 | atSharks | W3-2 | 2-0-0 | 4 PTS | O2 Arena · Prague, Czechia |
| 3 | Thu Oct 13 | vsStars | L1-4 | 2-1-0 | 4 PTS | Bridgestone Arena · Nashville, TN |
| 4 | Sat Oct 15 | atStars | L1-5 | 2-2-0 | 4 PTS | American Airlines Center · Dallas, TX |
| 5 | Tue Oct 18 | vsKings | L3-4 (SO) | 2-2-1 | 5 PTS | Bridgestone Arena · Nashville, TN |
| 6 | Thu Oct 20 | atJackets | L3-5 | 2-3-1 | 5 PTS | Nationwide Arena · Columbus, OH |
| 7 | Sat Oct 22 | vsFlyers | L1-3 | 2-4-1 | 5 PTS | Bridgestone Arena · Nashville, TN |
| 8 | Thu Oct 27 | vsBlues | W6-2 | 3-4-1 | 7 PTS | Bridgestone Arena · Nashville, TN |
| 9 | Sat Oct 29 | vsCapitals | L0-3 | 3-5-1 | 7 PTS | Bridgestone Arena · Nashville, TN |
| 10 | Tue Nov 1 | atOilers | L4-7 | 3-6-1 | 7 PTS | Rogers Place · Edmonton, AB |
| 11 | Thu Nov 3 | atFlames | W4-1 | 4-6-1 | 9 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 12 | Sat Nov 5 | atCanucks | W4-3 (SO) | 5-6-1 | 11 PTS | Rogers Arena · Vancouver, British Columbia |
| 13 | Tue Nov 8 | atKraken | L1-5 | 5-7-1 | 11 PTS | Climate Pledge Arena · Seattle, WA |
| 14 | Thu Nov 10 | atAvalanche | L3-5 | 5-8-1 | 11 PTS | Ball Arena · Denver, CO |
| 15 | Sat Nov 12 | vsRangers | W2-1 | 6-8-1 | 13 PTS | Bridgestone Arena · Nashville, TN |
| 16 | Tue Nov 15 | vsWild | W2-1 | 7-8-1 | 15 PTS | Bridgestone Arena · Nashville, TN |
| 17 | Thu Nov 17 | vsIslanders | W5-4 | 8-8-1 | 17 PTS | Bridgestone Arena · Nashville, TN |
| 18 | Sat Nov 19 | vsLightning | L2-3 (OT) | 8-8-2 | 18 PTS | Bridgestone Arena · Nashville, TN |
| 19 | Mon Nov 21 | vsCoyotes | W4-3 (SO) | 9-8-2 | 20 PTS | Bridgestone Arena · Nashville, TN |
| 20 | Wed Nov 23 | atRed Wings | L0-3 | 9-9-2 | 20 PTS | Little Caesars Arena · Detroit, MI |
| 21 | Tue Nov 29 | vsDucks | W2-1 (OT) | 10-9-2 | 22 PTS | Bridgestone Arena · Nashville, TN |
| 22 | Thu Dec 1 | atDevils | W4-3 (OT) | 11-9-2 | 24 PTS | Prudential Center · Newark, NJ |
| 23 | Fri Dec 2 | atIslanders | W4-1 | 12-9-2 | 26 PTS | UBS Arena · Elmont, NY |
| 24 | Thu Dec 8 | atLightning | L2-5 | 12-10-2 | 26 PTS | AMALIE Arena · Tampa, FL |
| 25 | Sat Dec 10 | vsSenators | L2-3 | 12-11-2 | 26 PTS | Bridgestone Arena · Nashville, TN |
| 26 | Mon Dec 12 | atBlues | L0-1 (OT) | 12-11-3 | 27 PTS | Enterprise Center · St. Louis, MO |
| 27 | Tue Dec 13 | vsOilers | L3-6 | 12-12-3 | 27 PTS | Bridgestone Arena · Nashville, TN |
| 28 | Thu Dec 15 | atJets | L1-2 (OT) | 12-12-4 | 28 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 29 | Sat Dec 17 | atAvalanche | L1-3 | 12-13-4 | 28 PTS | Ball Arena · Denver, CO |
| 30 | Mon Dec 19 | vsOilers | W4-3 (OT) | 13-13-4 | 30 PTS | Bridgestone Arena · Nashville, TN |
| 31 | Wed Dec 21 | atBlackhawks | W4-2 | 14-13-4 | 32 PTS | United Center · Chicago, IL |
| 32 | Fri Dec 23 | vsAvalanche | L2-3 (OT) | 14-13-5 | 33 PTS | Bridgestone Arena · Nashville, TN |
| 33 | Tue Dec 27 | vsStars | L2-3 | 14-14-5 | 33 PTS | Bridgestone Arena · Nashville, TN |
| 34 | Fri Dec 30 | atDucks | W6-1 | 15-14-5 | 35 PTS | Honda Center · Anaheim, CA |
| 35 | Sat Dec 31 | atKnights | L4-5 (OT) | 15-14-6 | 36 PTS | T-Mobile Arena · Las Vegas, NV |
| 36 | Tue Jan 3 | vsCanadiens | W6-3 | 16-14-6 | 38 PTS | Bridgestone Arena · Nashville, TN |
| 37 | Thu Jan 5 | atHurricanes | W5-3 | 17-14-6 | 40 PTS | PNC Arena · Raleigh, NC |
| 38 | Fri Jan 6 | atCapitals | W3-2 | 18-14-6 | 42 PTS | Capital One Arena · Washington, D.C. |
| 39 | Mon Jan 9 | atSenators | W3-0 | 19-14-6 | 44 PTS | Canadian Tire Centre · Ottawa, ON |
| 40 | Wed Jan 11 | atMaple Leafs | L1-2 | 19-15-6 | 44 PTS | Scotiabank Arena · Toronto, ON |
| 41 | Thu Jan 12 | atCanadiens | L3-4 | 19-16-6 | 44 PTS | Bell Centre · Montreal, QC |
| 42 | Sat Jan 14 | vsSabres | L3-5 | 19-17-6 | 44 PTS | Bridgestone Arena · Nashville, TN |
| 43 | Mon Jan 16 | vsFlames | W2-1 | 20-17-6 | 46 PTS | Bridgestone Arena · Nashville, TN |
| 44 | Tue Jan 17 | vsJackets | W2-1 | 21-17-6 | 48 PTS | Bridgestone Arena · Nashville, TN |
| 45 | Thu Jan 19 | atBlues | L2-5 | 21-18-6 | 48 PTS | Enterprise Center · St. Louis, MO |
| 46 | Sat Jan 21 | vsKings | W5-3 | 22-18-6 | 50 PTS | Bridgestone Arena · Nashville, TN |
| 47 | Tue Jan 24 | vsJets | W2-1 | 23-18-6 | 52 PTS | Bridgestone Arena · Nashville, TN |
| 48 | Thu Jan 26 | vsDevils | W6-4 | 24-18-6 | 54 PTS | Bridgestone Arena · Nashville, TN |
| 49 | Tue Feb 7 | vsKnights | L1-5 | 24-19-6 | 54 PTS | Bridgestone Arena · Nashville, TN |
| 50 | Sat Feb 11 | atFlyers | W2-1 (OT) | 25-19-6 | 56 PTS | Wells Fargo Center · Philadelphia, PA |
| 51 | Mon Feb 13 | vsCoyotes | L2-4 | 25-20-6 | 56 PTS | Bridgestone Arena · Nashville, TN |
| 52 | Thu Feb 16 | vsBruins | L0-5 | 25-21-6 | 56 PTS | Bridgestone Arena · Nashville, TN |
| 53 | Sat Feb 18 | vsPanthers | W7-3 | 26-21-6 | 58 PTS | Bridgestone Arena · Nashville, TN |
| 54 | Sun Feb 19 | atWild | L3-4 | 26-22-6 | 58 PTS | Xcel Energy Center · St. Paul, MN |
| 55 | Tue Feb 21 | vsCanucks | W5-4 (SO) | 27-22-6 | 60 PTS | Bridgestone Arena · Nashville, TN |
| 56 | Thu Feb 23 | atSharks | W6-2 | 28-22-6 | 62 PTS | SAP Center · San Jose, CA |
| 57 | Sun Feb 26 | atCoyotes | W6-2 | 29-22-6 | 64 PTS | Mullett Arena · Tempe, AZ |
| 58 | Tue Feb 28 | vsPenguins | L1-3 | 29-23-6 | 64 PTS | Bridgestone Arena · Nashville, TN |
| 59 | Thu Mar 2 | atPanthers | W2-1 | 30-23-6 | 66 PTS | Amerant Bank Arena · Sunrise, FL |
| 60 | Sat Mar 4 | atBlackhawks | W3-1 | 31-23-6 | 68 PTS | United Center · Chicago, IL |
| 61 | Mon Mar 6 | atCanucks | L3-4 (SO) | 31-23-7 | 69 PTS | Rogers Arena · Vancouver, British Columbia |
| 62 | Thu Mar 9 | atCoyotes | L1-4 | 31-24-7 | 69 PTS | Mullett Arena · Tempe, AZ |
| 63 | Sat Mar 11 | atKings | W2-1 (SO) | 32-24-7 | 71 PTS | Crypto.com Arena · Los Angeles, CA |
| 64 | Sun Mar 12 | atDucks | W5-4 (OT) | 33-24-7 | 73 PTS | Honda Center · Anaheim, CA |
| 65 | Tue Mar 14 | vsRed Wings | W2-1 | 34-24-7 | 75 PTS | Bridgestone Arena · Nashville, TN |
| 66 | Thu Mar 16 | vsBlackhawks | L1-2 | 34-25-7 | 75 PTS | Bridgestone Arena · Nashville, TN |
| 67 | Sat Mar 18 | vsJets | L2-3 (OT) | 34-25-8 | 76 PTS | Bridgestone Arena · Nashville, TN |
| 68 | Sun Mar 19 | atRangers | L0-7 | 34-26-8 | 76 PTS | Madison Square Garden · Manhattan, NY |
| 69 | Tue Mar 21 | atSabres | W7-3 | 35-26-8 | 78 PTS | KeyBank Center · Buffalo, NY |
| 70 | Thu Mar 23 | vsKraken | W2-1 (SO) | 36-26-8 | 80 PTS | Bridgestone Arena · Nashville, TN |
| 71 | Sat Mar 25 | vsKraken | L2-7 | 36-27-8 | 80 PTS | Bridgestone Arena · Nashville, TN |
| 72 | Sun Mar 26 | vsMaple Leafs | L2-3 | 36-28-8 | 80 PTS | Bridgestone Arena · Nashville, TN |
| 73 | Tue Mar 28 | atBruins | W2-1 | 37-28-8 | 82 PTS | TD Garden · Boston, MA |
| 74 | Thu Mar 30 | atPenguins | L0-2 | 37-29-8 | 82 PTS | PPG Paints Arena · Pittsburgh, PA |
| 75 | Sat Apr 1 | vsBlues | W6-1 | 38-29-8 | 84 PTS | Bridgestone Arena · Nashville, TN |
| 76 | Mon Apr 3 | atStars | L1-5 | 38-30-8 | 84 PTS | American Airlines Center · Dallas, TX |
| 77 | Tue Apr 4 | vsKnights | W3-2 (OT) | 39-30-8 | 86 PTS | Bridgestone Arena · Nashville, TN |
| 78 | Thu Apr 6 | vsHurricanes | W3-0 | 40-30-8 | 88 PTS | Bridgestone Arena · Nashville, TN |
| 79 | Sat Apr 8 | atJets | L0-2 | 40-31-8 | 88 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 80 | Mon Apr 10 | atFlames | W3-2 (SO) | 41-31-8 | 90 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 81 | Thu Apr 13 | vsWild | W4-3 (OT) | 42-31-8 | 92 PTS | Bridgestone Arena · Nashville, TN |
| 82 | Fri Apr 14 | vsAvalanche | L3-4 | 42-32-8 | 92 PTS | Bridgestone Arena · Nashville, TN |
