| 1 | Tue Apr 5 | vs Astros | L3-5 | 0-1 | .000 | Yankee Stadium · The Bronx, NY |
| 2 | Wed Apr 6 | vs Astros | W16-6 | 1-1 | .500 | Yankee Stadium · The Bronx, NY |
| 3 | Thu Apr 7 | vs Astros | W8-5 | 2-1 | .667 | Yankee Stadium · The Bronx, NY |
| 4 | Fri Apr 8 | at Tigers | L0-4 | 2-2 | .500 | Comerica Park · Detroit, MI |
| 5 | Sat Apr 9 | at Tigers | W8-4 | 3-2 | .600 | Comerica Park · Detroit, MI |
| 6 | Tue Apr 12 | at Blue Jays | W3-2 | 4-2 | .667 | Rogers Centre · Toronto, ON |
| 7 | Wed Apr 13 | at Blue Jays | L2-7 | 4-3 | .571 | Rogers Centre · Toronto, ON |
| 8 | Thu Apr 14 | at Blue Jays | L2-4 | 4-4 | .500 | Rogers Centre · Toronto, ON |
| 9 | Fri Apr 15 | vs Mariners | L1-7 | 4-5 | .444 | Yankee Stadium · The Bronx, NY |
| 10 | Sat Apr 16 | vs Mariners | L2-3 | 4-6 | .400 | Yankee Stadium · The Bronx, NY |
| 11 | Sun Apr 17 | vs Mariners | W4-3 | 5-6 | .455 | Yankee Stadium · The Bronx, NY |
| 12 | Tue Apr 19 | vs Athletics | L2-3 (11) | 5-7 | .417 | Yankee Stadium · The Bronx, NY |
| 13 | Wed Apr 20 | vs Athletics | L2-5 | 5-8 | .385 | Yankee Stadium · The Bronx, NY |
| 14 | Thu Apr 21 | vs Athletics | L3-7 | 5-9 | .357 | Yankee Stadium · The Bronx, NY |
| 15 | Fri Apr 22 | vs Rays | W6-3 | 6-9 | .400 | Yankee Stadium · The Bronx, NY |
| 16 | Sat Apr 23 | vs Rays | W3-2 | 7-9 | .438 | Yankee Stadium · The Bronx, NY |
| 17 | Sun Apr 24 | vs Rays | L1-8 | 7-10 | .412 | Yankee Stadium · The Bronx, NY |
| 18 | Mon Apr 25 | at Rangers | W3-1 | 8-10 | .444 | Globe Life Field · Arlington, TX |
| 19 | Tue Apr 26 | at Rangers | L1-10 | 8-11 | .421 | Globe Life Field · Arlington, TX |
| 20 | Wed Apr 27 | at Rangers | L2-3 | 8-12 | .400 | Globe Life Field · Arlington, TX |
| 21 | Fri Apr 29 | at Red Sox | L2-4 | 8-13 | .381 | Fenway Park · Boston, MA |
| 22 | Sat Apr 30 | at Red Sox | L0-8 | 8-14 | .364 | Fenway Park · Boston, MA |
| 23 | Sun May 1 | at Red Sox | L7-8 | 8-15 | .348 | Fenway Park · Boston, MA |
| 24 | Tue May 3 | at Orioles | L1-4 | 8-16 | .333 | Camden Yards · Baltimore, MD |
| 25 | Wed May 4 | at Orioles | W7-0 | 9-16 | .360 | Camden Yards · Baltimore, MD |
| 26 | Thu May 5 | at Orioles | L0-1 (10) | 9-17 | .346 | Camden Yards · Baltimore, MD |
| 27 | Fri May 6 | vs Red Sox | W3-2 | 10-17 | .370 | Yankee Stadium · The Bronx, NY |
| 28 | Sat May 7 | vs Red Sox | W8-2 | 11-17 | .393 | Yankee Stadium · The Bronx, NY |
| 29 | Sun May 8 | vs Red Sox | L1-5 | 11-18 | .379 | Yankee Stadium · The Bronx, NY |
| 30 | Mon May 9 | vs Royals | W6-3 | 12-18 | .400 | Yankee Stadium · The Bronx, NY |
| 31 | Tue May 10 | vs Royals | W10-7 | 13-18 | .419 | Yankee Stadium · The Bronx, NY |
| 32 | Wed May 11 | vs Royals | L3-7 | 13-19 | .406 | Yankee Stadium · The Bronx, NY |
| 33 | Thu May 12 | vs Royals | W7-3 | 14-19 | .424 | Yankee Stadium · The Bronx, NY |
| 34 | Fri May 13 | vs White Sox | L1-7 | 14-20 | .412 | Yankee Stadium · The Bronx, NY |
| 35 | Sat May 14 | vs White Sox | W2-1 | 15-20 | .429 | Yankee Stadium · The Bronx, NY |
| 36 | Sun May 15 | vs White Sox | W7-5 | 16-20 | .444 | Yankee Stadium · The Bronx, NY |
| 37 | Mon May 16 | at D-backs | L2-12 | 16-21 | .432 | Chase Field · Phoenix, AZ |
| 38 | Tue May 17 | at D-backs | L3-5 | 16-22 | .421 | Chase Field · Phoenix, AZ |
| 39 | Wed May 18 | at D-backs | W4-2 | 17-22 | .436 | Chase Field · Phoenix, AZ |
| 40 | Thu May 19 | at Athletics | W4-1 | 18-22 | .450 | RingCentral Coliseum · Oakland, CA |
| 41 | Fri May 20 | at Athletics | W8-3 | 19-22 | .463 | RingCentral Coliseum · Oakland, CA |
| 42 | Sat May 21 | at Athletics | W5-1 | 20-22 | .476 | RingCentral Coliseum · Oakland, CA |
| 43 | Sun May 22 | at Athletics | W5-4 | 21-22 | .488 | RingCentral Coliseum · Oakland, CA |
| 44 | Tue May 24 | vs Blue Jays | W6-0 | 22-22 | .500 | Yankee Stadium · The Bronx, NY |
| 45 | Wed May 25 | vs Blue Jays | L4-8 | 22-23 | .489 | Yankee Stadium · The Bronx, NY |
| 46 | Thu May 26 | vs Blue Jays | L1-3 | 22-24 | .478 | Yankee Stadium · The Bronx, NY |
| 47 | Fri May 27 | at Rays | W4-1 | 23-24 | .489 | Tropicana Field · St. Petersburg, FL |
| 48 | Sat May 28 | at Rays | L5-9 | 23-25 | .479 | Tropicana Field · St. Petersburg, FL |
| 49 | Sun May 29 | at Rays | W2-1 | 24-25 | .490 | Tropicana Field · St. Petersburg, FL |
| 50 | Mon May 30 | at Blue Jays | L2-4 | 24-26 | .480 | Rogers Centre · Toronto, ON |
| 51 | Tue May 31 | at Blue Jays | L1-4 | 24-27 | .471 | Rogers Centre · Toronto, ON |
| 52 | Wed Jun 1 | at Blue Jays | L0-7 | 24-28 | .462 | Rogers Centre · Toronto, ON |
| 53 | Thu Jun 2 | at Tigers | W5-4 | 25-28 | .472 | Comerica Park · Detroit, MI |
| 54 | Fri Jun 3 | at Orioles | L5-6 | 25-29 | .463 | Camden Yards · Baltimore, MD |
| 55 | Sat Jun 4 | at Orioles | W8-6 | 26-29 | .473 | Camden Yards · Baltimore, MD |
| 56 | Sun Jun 5 | at Orioles | L1-3 | 26-30 | .464 | Camden Yards · Baltimore, MD |
| 57 | Mon Jun 6 | vs Angels | W5-2 | 27-30 | .474 | Yankee Stadium · The Bronx, NY |
| 58 | Tue Jun 7 | vs Angels | W6-3 | 28-30 | .483 | Yankee Stadium · The Bronx, NY |
| 59 | Wed Jun 8 | vs Angels | W12-6 | 29-30 | .492 | Yankee Stadium · The Bronx, NY |
| 60 | Thu Jun 9 | vs Angels | W6-3 | 30-30 | .500 | Yankee Stadium · The Bronx, NY |
| 61 | Fri Jun 10 | vs Tigers | W4-0 | 31-30 | .508 | Yankee Stadium · The Bronx, NY |
| 62 | Sat Jun 11 | vs Tigers | L1-6 | 31-31 | .500 | Yankee Stadium · The Bronx, NY |
| 63 | Sun Jun 12 | vs Tigers | L1-4 | 31-32 | .492 | Yankee Stadium · The Bronx, NY |
| 64 | Tue Jun 14 | at Rockies | L10-13 | 31-33 | .484 | Coors Field · Denver, CO |
| 65 | Wed Jun 15 | at Rockies | L3-6 | 31-34 | .477 | Coors Field · Denver, CO |
| 66 | Thu Jun 16 | at Twins | W4-1 | 32-34 | .485 | Target Field · Minneapolis, MN |
| 67 | Fri Jun 17 | at Twins | W8-2 | 33-34 | .493 | Target Field · Minneapolis, MN |
| 68 | Sat Jun 18 | at Twins | W7-6 | 34-34 | .500 | Target Field · Minneapolis, MN |
| 69 | Sun Jun 19 | at Twins | L4-7 | 34-35 | .493 | Target Field · Minneapolis, MN |
| 70 | Tue Jun 21 | vs Rockies | L4-8 | 34-36 | .486 | Yankee Stadium · The Bronx, NY |
| 71 | Wed Jun 22 | vs Rockies | W9-8 | 35-36 | .493 | Yankee Stadium · The Bronx, NY |
| 72 | Fri Jun 24 | vs Twins | W5-3 | 36-36 | .500 | Yankee Stadium · The Bronx, NY |
| 73 | Sat Jun 25 | vs Twins | W2-1 | 37-36 | .507 | Yankee Stadium · The Bronx, NY |
| 74 | Sun Jun 26 | vs Twins | L1-7 | 37-37 | .500 | Yankee Stadium · The Bronx, NY |
| 75 | Mon Jun 27 | vs Rangers | L6-9 | 37-38 | .493 | Yankee Stadium · The Bronx, NY |
| 76 | Tue Jun 28 | vs Rangers | L1-7 | 37-39 | .487 | Yankee Stadium · The Bronx, NY |
| 77 | Wed Jun 29 | vs Rangers | W9-7 | 38-39 | .494 | Yankee Stadium · The Bronx, NY |
| 78 | Thu Jun 30 | vs Rangers | W2-1 | 39-39 | .500 | Yankee Stadium · The Bronx, NY |
| 79 | Fri Jul 1 | at Padres | L6-7 | 39-40 | .494 | Petco Park · San Diego, CA |
| 80 | Sat Jul 2 | at Padres | L1-2 | 39-41 | .487 | Petco Park · San Diego, CA |
| 81 | Sun Jul 3 | at Padres | W6-3 | 40-41 | .494 | Petco Park · San Diego, CA |
| 82 | Mon Jul 4 | at White Sox | L2-8 | 40-42 | .488 | Guaranteed Rate Field · Chicago, IL |
| 83 | Tue Jul 5 | at White Sox | W9-0 | 41-42 | .494 | Guaranteed Rate Field · Chicago, IL |
| 84 | Wed Jul 6 | at White Sox | L0-5 | 41-43 | .488 | Guaranteed Rate Field · Chicago, IL |
| 85 | Thu Jul 7 | at Guardians | W5-4 | 42-43 | .494 | Progressive Field · Cleveland, OH |
| 86 | Fri Jul 8 | at Guardians | L2-10 | 42-44 | .488 | Progressive Field · Cleveland, OH |
| 87 | Sat Jul 9 | at Guardians | W7-6 (11) | 43-44 | .494 | Progressive Field · Cleveland, OH |
| 88 | Sun Jul 10 | at Guardians | W11-7 | 44-44 | .500 | Progressive Field · Cleveland, OH |
| 89 | Fri Jul 15 | vs Red Sox | L3-5 | 44-45 | .494 | Yankee Stadium · The Bronx, NY |
| 90 | Sat Jul 16 | vs Red Sox | L2-5 | 44-46 | .489 | Yankee Stadium · The Bronx, NY |
| 91 | Sun Jul 17 | vs Red Sox | W3-1 | 45-46 | .495 | Yankee Stadium · The Bronx, NY |
| 92 | Mon Jul 18 | vs Orioles | W2-1 | 46-46 | .500 | Yankee Stadium · The Bronx, NY |
| 93 | Tue Jul 19 | vs Orioles | W7-1 | 47-46 | .505 | Yankee Stadium · The Bronx, NY |
| 94 | Wed Jul 20 | vs Orioles | W5-0 | 48-46 | .511 | Yankee Stadium · The Bronx, NY |
| 95 | Thu Jul 21 | vs Orioles | L1-4 | 48-47 | .505 | Yankee Stadium · The Bronx, NY |
| 96 | Fri Jul 22 | vs Giants | W3-2 | 49-47 | .510 | Yankee Stadium · The Bronx, NY |
| 97 | Sat Jul 23 | vs Giants | L1-2 (12) | 49-48 | .505 | Yankee Stadium · The Bronx, NY |
| 98 | Sun Jul 24 | vs Giants | W5-2 | 50-48 | .510 | Yankee Stadium · The Bronx, NY |
| 99 | Mon Jul 25 | at Astros | W2-1 | 51-48 | .515 | Minute Maid Park · Houston, TX |
| 100 | Tue Jul 26 | at Astros | W6-3 | 52-48 | .520 | Minute Maid Park · Houston, TX |
| 101 | Wed Jul 27 | at Astros | L1-4 | 52-49 | .515 | Minute Maid Park · Houston, TX |
| 102 | Fri Jul 29 | at Rays | L1-5 | 52-50 | .510 | Tropicana Field · St. Petersburg, FL |
| 103 | Sat Jul 30 | at Rays | L3-6 | 52-51 | .505 | Tropicana Field · St. Petersburg, FL |
| 104 | Sun Jul 31 | at Rays | L3-5 | 52-52 | .500 | Tropicana Field · St. Petersburg, FL |
| 105 | Mon Aug 1 | at Mets | W6-5 (10) | 53-52 | .505 | Citi Field · Queens, NY |
| 106 | Tue Aug 2 | at Mets | L1-7 | 53-53 | .500 | Citi Field · Queens, NY |
| 107 | Wed Aug 3 | vs Mets | W9-5 | 54-53 | .505 | Yankee Stadium · The Bronx, NY |
| 108 | Thu Aug 4 | vs Mets | L1-4 | 54-54 | .500 | Yankee Stadium · The Bronx, NY |
| 109 | Fri Aug 5 | vs Guardians | W13-7 | 55-54 | .505 | Yankee Stadium · The Bronx, NY |
| 110 | Sat Aug 6 | vs Guardians | L2-5 | 55-55 | .500 | Yankee Stadium · The Bronx, NY |
| 111 | Sun Aug 7 | vs Guardians | W3-2 | 56-55 | .505 | Yankee Stadium · The Bronx, NY |
| 112 | Tue Aug 9 | at Red Sox | L3-5 | 56-56 | .500 | Fenway Park · Boston, MA |
| 113 | Wed Aug 10 | at Red Sox | W9-4 | 57-56 | .504 | Fenway Park · Boston, MA |
| 114 | Thu Aug 11 | at Red Sox | W4-2 | 58-56 | .509 | Fenway Park · Boston, MA |
| 115 | Fri Aug 12 | vs Rays | W6-3 | 59-56 | .513 | Yankee Stadium · The Bronx, NY |
| 116 | Sat Aug 13 | vs Rays | W8-4 | 60-56 | .517 | Yankee Stadium · The Bronx, NY |
| 117 | Sun Aug 14 | vs Rays | L3-12 | 60-57 | .513 | Yankee Stadium · The Bronx, NY |
| 118 | Mon Aug 15 | vs Blue Jays | W1-0 | 61-57 | .517 | Yankee Stadium · The Bronx, NY |
| 119 | Tue Aug 16 | vs Blue Jays | L6-12 | 61-58 | .513 | Yankee Stadium · The Bronx, NY |
| 120 | Wed Aug 17 | vs Blue Jays | L4-7 | 61-59 | .508 | Yankee Stadium · The Bronx, NY |
| 121 | Fri Aug 19 | at Angels | W7-0 | 62-59 | .512 | Angel Stadium · Anaheim, CA |
| 122 | Sat Aug 20 | at Angels | W5-1 | 63-59 | .516 | Angel Stadium · Anaheim, CA |
| 123 | Sun Aug 21 | at Angels | L0-2 | 63-60 | .512 | Angel Stadium · Anaheim, CA |
| 124 | Mon Aug 22 | at Mariners | L5-7 | 63-61 | .508 | T-Mobile Park · Seattle, WA |
| 125 | Tue Aug 23 | at Mariners | W5-1 | 64-61 | .512 | T-Mobile Park · Seattle, WA |
| 126 | Wed Aug 24 | at Mariners | W5-0 | 65-61 | .516 | T-Mobile Park · Seattle, WA |
| 127 | Fri Aug 26 | vs Orioles | W14-4 | 66-61 | .520 | Yankee Stadium · The Bronx, NY |
| 128 | Sat Aug 27 | vs Orioles | W13-5 | 67-61 | .523 | Yankee Stadium · The Bronx, NY |
| 129 | Sun Aug 28 | vs Orioles | L0-5 | 67-62 | .519 | Yankee Stadium · The Bronx, NY |
| 130 | Mon Aug 29 | at Royals | L5-8 | 67-63 | .515 | Kauffman Stadium · Kansas City, MO |
| 131 | Tue Aug 30 | at Royals | W5-4 (10) | 68-63 | .519 | Kauffman Stadium · Kansas City, MO |
| 132 | Wed Aug 31 | at Royals | W5-4 (13) | 69-63 | .523 | Kauffman Stadium · Kansas City, MO |
| 133 | Fri Sep 2 | at Orioles | L0-8 | 69-64 | .519 | Camden Yards · Baltimore, MD |
| 134 | Sat Sep 3 | at Orioles | L0-2 | 69-65 | .515 | Camden Yards · Baltimore, MD |
| 135 | Sun Sep 4 | at Orioles | W5-2 | 70-65 | .519 | Camden Yards · Baltimore, MD |
| 136 | Mon Sep 5 | vs Blue Jays | W5-3 | 71-65 | .522 | Yankee Stadium · The Bronx, NY |
| 137 | Tue Sep 6 | vs Blue Jays | W7-6 | 72-65 | .526 | Yankee Stadium · The Bronx, NY |
| 138 | Wed Sep 7 | vs Blue Jays | W2-0 | 73-65 | .529 | Yankee Stadium · The Bronx, NY |
| 139 | Thu Sep 8 | vs Rays | W5-4 | 74-65 | .532 | Yankee Stadium · The Bronx, NY |
| 140 | Fri Sep 9 | vs Rays | W7-5 | 75-65 | .536 | Yankee Stadium · The Bronx, NY |
| 141 | Sat Sep 10 | vs Rays | W5-1 | 76-65 | .539 | Yankee Stadium · The Bronx, NY |
| 142 | Sun Sep 11 | vs Rays | L2-4 | 76-66 | .535 | Yankee Stadium · The Bronx, NY |
| 143 | Mon Sep 12 | vs Dodgers | L2-8 | 76-67 | .531 | Yankee Stadium · The Bronx, NY |
| 144 | Tue Sep 13 | vs Dodgers | W3-0 | 77-67 | .535 | Yankee Stadium · The Bronx, NY |
| 145 | Wed Sep 14 | vs Dodgers | L0-2 | 77-68 | .531 | Yankee Stadium · The Bronx, NY |
| 146 | Thu Sep 15 | at Red Sox | L5-7 | 77-69 | .527 | Fenway Park · Boston, MA |
| 147 | Fri Sep 16 | at Red Sox | L4-7 | 77-70 | .524 | Fenway Park · Boston, MA |
| 148 | Sat Sep 17 | at Red Sox | L5-6 | 77-71 | .520 | Fenway Park · Boston, MA |
| 149 | Sun Sep 18 | at Red Sox | L4-5 | 77-72 | .517 | Fenway Park · Boston, MA |
| 150 | Tue Sep 20 | at Rays | W5-3 | 78-72 | .520 | Tropicana Field · St. Petersburg, FL |
| 151 | Wed Sep 21 | at Rays | W11-5 | 79-72 | .523 | Tropicana Field · St. Petersburg, FL |
| 152 | Thu Sep 22 | at Rays | L0-2 | 79-73 | .520 | Tropicana Field · St. Petersburg, FL |
| 153 | Fri Sep 23 | at Blue Jays | L0-9 | 79-74 | .516 | Rogers Centre · Toronto, ON |
| 154 | Sat Sep 24 | at Blue Jays | L0-3 | 79-75 | .513 | Rogers Centre · Toronto, ON |
| 155 | Sun Sep 25 | at Blue Jays | L3-4 | 79-76 | .510 | Rogers Centre · Toronto, ON |
| 156 | Mon Sep 26 | at Blue Jays | W7-5 | 80-76 | .513 | Rogers Centre · Toronto, ON |
| 157 | Tue Sep 27 | vs Red Sox | W6-4 | 81-76 | .516 | Yankee Stadium · The Bronx, NY |
| 158 | Wed Sep 28 | vs Red Sox | W5-3 | 82-76 | .519 | Yankee Stadium · The Bronx, NY |
| 159 | Thu Sep 29 | vs Red Sox | W5-1 | 83-76 | .522 | Yankee Stadium · The Bronx, NY |
| 160 | Fri Sep 30 | vs Orioles | L1-8 | 83-77 | .519 | Yankee Stadium · The Bronx, NY |
| 161 | Sat Oct 1 | vs Orioles | W7-3 | 84-77 | .522 | Yankee Stadium · The Bronx, NY |
| 162 | Sun Oct 2 | vs Orioles | L2-5 | 84-78 | .519 | Yankee Stadium · The Bronx, NY |