| 1 | Mon Nov 7 | at N Kentucky | W79-57 | 1-0 | 1.000 | - | | Truist Arena · Highland Heights, KY |
| 2 | Thu Nov 10 | vs TBD | W76-55 | 2-0 | 1.000 | - | | M.A.C. Center · Kent, OH |
| 3 | Mon Nov 14 | vs Portland | W77-65 | 3-0 | 1.000 | - | | M.A.C. Center · Kent, OH |
| 4 | Wed Nov 16 | vs AR-Pine Bluff | W94-68 | 4-0 | 1.000 | - | | M.A.C. Center · Kent, OH |
| 5 | Sat Nov 19 | vs Chicago St | W88-59 | 5-0 | 1.000 | - | | M.A.C. Center · Kent, OH |
| 6 | Wed Nov 23 | at Charleston | L72-74 | 5-1 | .833 | - | | TD Arena · Charleston, SC |
| 7 | Sat Nov 26 | at #2Houston | L44-49 | 5-2 | .714 | - | | Fertitta Center · Houston, TX |
| 8 | Fri Dec 2 | vs S Dakota St | W83-68 | 6-2 | .750 | - | | M.A.C. Center · Kent, OH |
| 9 | Mon Dec 5 | at #18Gonzaga | L66-73 | 6-3 | .667 | - | | McCarthey Athletic Center · Spokane, WA |
| 10 | Sat Dec 10 | at Cleveland St | W67-58 | 7-3 | .700 | - | | Wolstein Center · Cleveland, OH |
| 11 | Sun Dec 18 | vsTBD | W106-56 | 8-3 | .727 | - | | M.A.C. Center · Kent, OH |
| 12 | Wed Dec 21 | vs New Mexico St | W73-63 | 9-3 | .750 | - | | M.A.C. Center · Kent, OH |
| 13 | Thu Dec 22 | at UTEP | W47-46 | 10-3 | .769 | - | | Don Haskins Center · El Paso, TX |
| 14 | Tue Jan 3 | vs W Michigan | W80-72 | 11-3 | .786 | - | | M.A.C. Center · Kent, OH |
| 15 | Sat Jan 7 | at Miami OH | W69-66 | 12-3 | .800 | - | | Millett Hall · Oxford, OH |
| 16 | Tue Jan 10 | vs Toledo | W75-63 | 13-3 | .813 | - | | M.A.C. Center · Kent, OH |
| 17 | Fri Jan 13 | at Ohio | W70-65 | 14-3 | .824 | - | CBS | Convocation Center (OH) · Athens, OH |
| 18 | Tue Jan 17 | at E Michigan | W77-63 | 15-3 | .833 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 19 | Fri Jan 20 | vs Ball State | W86-65 | 16-3 | .842 | - | CBS | M.A.C. Center · Kent, OH |
| 20 | Tue Jan 24 | at N Illinois | L76-86 | 16-4 | .800 | - | | NIU Convocation Center · Dekalb, IL |
| 21 | Fri Jan 27 | vs Buffalo | W74-68 | 17-4 | .810 | - | ESPNU | M.A.C. Center · Kent, OH |
| 22 | Tue Jan 31 | vs C Michigan | W81-69 | 18-4 | .818 | - | | M.A.C. Center · Kent, OH |
| 23 | Fri Feb 3 | at Akron | L55-67 | 18-5 | .783 | - | ESPNU | James A. Rhodes Arena · Akron, OH |
| 24 | Tue Feb 7 | vs Bowling Green | W87-64 | 19-5 | .792 | - | | M.A.C. Center · Kent, OH |
| 25 | Fri Feb 10 | atBuffalo | W72-65 | 20-5 | .800 | - | ESPN2 | Alumni Arena · Buffalo, NY |
| 26 | Tue Feb 14 | atW Michigan | W82-58 | 21-5 | .808 | - | | University Arena (MI) · Kalamazoo, MI |
| 27 | Fri Feb 17 | vsE Michigan | W81-54 | 22-5 | .815 | - | CBS | M.A.C. Center · Kent, OH |
| 28 | Tue Feb 21 | atBall State | L70-82 | 22-6 | .786 | - | | Worthen Arena · Muncie, IN |
| 29 | Sat Feb 25 | atBowling Green | W79-69 | 23-6 | .793 | - | | Stroh Center · Bowling Green, OH |
| 30 | Tue Feb 28 | vsOhio | W82-75 | 24-6 | .800 | - | | M.A.C. Center · Kent, OH |
| 31 | Fri Mar 3 | vsAkron | W89-84 (OT) | 25-6 | .806 | - | ESPNU | M.A.C. Center · Kent, OH |
| 32 | Thu Mar 9 | vsN Illinois | W76-57 | 26-6 | .813 | - | | M.A.C. Center · Kent, OH |
| 33 | Fri Mar 10 | vsAkron | W79-73 | 27-6 | .818 | - | CBS | M.A.C. Center · Kent, OH |
| 34 | Sat Mar 11 | atToledo | W93-78 | 28-6 | .824 | - | ESPN2 | Savage Arena · Toledo, OH |
| 35 | Fri Mar 17 | at #4Indiana | L60-71 | 28-7 | .800 | #13 | TBS | Simon Skjodt Assembly Hall · Bloomington, IN |
