| 1 | Tue Nov 5 | at Boston Univ | W72-67 | 1-0 | 1.000 | - | | Case Gym · Boston, MA |
| 2 | Fri Nov 8 | vs Harvard | W84-79 | 2-0 | 1.000 | - | | Matthews Arena · Boston, MA |
| 3 | Tue Nov 12 | at UMass | L71-80 | 2-1 | .667 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 4 | Sat Nov 16 | vs Old Dominion | L69-76 | 2-2 | .500 | - | | Matthews Arena · Boston, MA |
| 5 | Tue Nov 19 | at Holy Cross | W101-44 | 3-2 | .600 | - | | Hart Center · Worcester, MA |
| 6 | Mon Nov 25 | vs South Alabama | L62-74 | 3-3 | .500 | - | | Matthews Arena · Boston, MA |
| 7 | Tue Nov 26 | vs Drake | L56-59 | 3-4 | .429 | - | | Matthews Arena · Boston, MA |
| 8 | Wed Nov 27 | vs Weber St | W79-69 | 4-4 | .500 | - | | Matthews Arena · Boston, MA |
| 9 | Wed Dec 4 | vs Maine | W78-63 | 5-4 | .556 | - | | Matthews Arena · Boston, MA |
| 10 | Sat Dec 7 | vs Davidson | L63-70 | 5-5 | .500 | - | | Matthews Arena · Boston, MA |
| 11 | Tue Dec 17 | at E Michigan | L55-60 | 5-6 | .455 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 12 | Thu Dec 19 | at Detroit Mercy | W74-61 | 6-6 | .500 | - | | Calihan Hall · Detroit, MI |
| 13 | Sat Dec 28 | at Towson | W61-45 | 7-6 | .538 | - | | SECU Arena · Towson, MD |
| 14 | Mon Dec 30 | at JMU | W88-72 | 8-6 | .571 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 15 | Thu Jan 2 | vs Elon | W77-68 | 9-6 | .600 | - | | Matthews Arena · Boston, MA |
| 16 | Sat Jan 4 | vs William & Mary | L64-66 | 9-7 | .563 | - | | Matthews Arena · Boston, MA |
| 17 | Thu Jan 9 | vs Hofstra | L72-74 | 9-8 | .529 | - | CBS | Matthews Arena · Boston, MA |
| 18 | Thu Jan 16 | at Charleston | W79-76 | 10-8 | .556 | - | | TD Arena · Charleston, SC |
| 19 | Sat Jan 18 | at UNC Wilmington | L74-76 (OT) | 10-9 | .526 | - | | Trask Coliseum · Wilmington, NC |
| 20 | Thu Jan 23 | vs Drexel | W85-52 | 11-9 | .550 | - | | Matthews Arena · Boston, MA |
| 21 | Sat Jan 25 | vs Delaware | L74-76 | 11-10 | .524 | - | | Matthews Arena · Boston, MA |
| 22 | Thu Jan 30 | atWilliam & Mary | L58-59 | 11-11 | .500 | - | | Kaplan Arena · Williamsburg, VA |
| 23 | Sat Feb 1 | atElon | L69-74 | 11-12 | .478 | - | | Schar Center · Elon, NC |
| 24 | Sat Feb 8 | atHofstra | L71-75 | 11-13 | .458 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 25 | Thu Feb 13 | vsUNC Wilmington | W71-63 | 12-13 | .480 | - | | Matthews Arena · Boston, MA |
| 26 | Sat Feb 15 | vsCharleston | W65-51 | 13-13 | .500 | - | | Matthews Arena · Boston, MA |
| 27 | Thu Feb 20 | atDelaware | L48-70 | 13-14 | .481 | - | | Bob Carpenter Center · Newark, DE |
| 28 | Sat Feb 22 | atDrexel | W77-68 | 14-14 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 29 | Thu Feb 27 | vsJMU | W77-57 | 15-14 | .517 | - | | Matthews Arena · Boston, MA |
| 30 | Sun Mar 1 | vsTowson | L72-75 | 15-15 | .500 | - | CBS | Matthews Arena · Boston, MA |
| 31 | Sun Mar 8 | atTowson | W72-62 | 16-15 | .516 | - | | SECU Arena · Towson, MD |
| 32 | Mon Mar 9 | vsElon | W68-60 | 17-15 | .531 | - | CBS | Matthews Arena · Boston, MA |
| 33 | Tue Mar 10 | atHofstra | L61-70 | 17-16 | .515 | - | CBS | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
