| 1 | Tue Nov 9 | at Colgate | L58-65 | 0-1 | .000 | - | | Cotterell Court · Hamilton, NY |
| 2 | Fri Nov 12 | at Georgia St | L64-83 | 0-2 | .000 | - | | GSU Convocation Center · Atlanta, GA |
| 3 | Tue Nov 16 | vs Boston Univ | W49-48 | 1-2 | .333 | - | | Matthews Arena · Boston, MA |
| 4 | Fri Nov 19 | at Duquesne | W71-55 | 2-2 | .500 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 5 | Sun Nov 21 | at S Illinois | W59-47 | 3-2 | .600 | - | | Banterra Center · Carbondale, IL |
| 6 | Mon Nov 22 | vs Colorado St | L61-71 | 3-3 | .500 | - | | Matthews Arena · Boston, MA |
| 7 | Sat Nov 27 | at Harvard | L57-77 | 3-4 | .429 | - | | Lavietes Pavilion · Cambridge, MA |
| 8 | Tue Nov 30 | vs Detroit Mercy | W66-56 | 4-4 | .500 | - | | Matthews Arena · Boston, MA |
| 9 | Fri Dec 3 | vsColgate | W74-69 | 5-4 | .556 | - | | Matthews Arena · Boston, MA |
| 10 | Tue Dec 7 | vs UMass | W82-76 | 6-4 | .600 | - | | Matthews Arena · Boston, MA |
| 11 | Sun Dec 12 | vs Davidson | L69-79 | 6-5 | .545 | - | | Matthews Arena · Boston, MA |
| 14 | Wed Dec 29 | at Elon | L62-79 | 6-6 | .500 | - | | Schar Center · Elon, NC |
| 15 | Fri Dec 31 | at William & Mary | L70-71 | 6-7 | .462 | - | | Kaplan Arena · Williamsburg, VA |
| 16 | Mon Jan 3 | vs Charleston | PPD | 9-22 | .290 | - | | Matthews Arena · Boston, MA |
| 17 | Wed Jan 5 | vs UNC Wilmington | PPD | 9-22 | .290 | - | | Matthews Arena · Boston, MA |
| 18 | Sun Jan 9 | at Towson | L67-70 | 6-8 | .429 | - | | SECU Arena · Towson, MD |
| 19 | Tue Jan 11 | at JMU | L66-89 | 6-9 | .400 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 20 | Sat Jan 15 | vs Drexel | L68-76 | 6-10 | .375 | - | | Matthews Arena · Boston, MA |
| 21 | Mon Jan 17 | vs Delaware | L76-82 (OT) | 6-11 | .353 | - | CBS | Matthews Arena · Boston, MA |
| 22 | Sat Jan 22 | vs Hofstra | L50-72 | 6-12 | .333 | - | | Matthews Arena · Boston, MA |
| 23 | Mon Jan 24 | vsUNC Wilmington | L68-74 | 6-13 | .316 | - | | Matthews Arena · Boston, MA |
| 24 | Thu Jan 27 | atUNC Wilmington | L62-67 | 6-14 | .300 | - | | Trask Coliseum · Wilmington, NC |
| 25 | Sat Jan 29 | atCharleston | L63-81 | 6-15 | .286 | - | | TD Arena · Charleston, SC |
| 26 | Thu Feb 3 | vsJMU | L71-76 | 6-16 | .273 | - | | Matthews Arena · Boston, MA |
| 27 | Sat Feb 5 | vsTowson | W58-53 | 7-16 | .304 | - | | Matthews Arena · Boston, MA |
| 28 | Thu Feb 10 | atDelaware | L61-74 | 7-17 | .292 | - | | Bob Carpenter Center · Newark, DE |
| 29 | Sat Feb 12 | atDrexel | L51-67 | 7-18 | .280 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 30 | Sat Feb 19 | atHofstra | L73-76 | 7-19 | .269 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 31 | Tue Feb 22 | vsCharleston | L72-83 | 7-20 | .259 | - | | Matthews Arena · Boston, MA |
| 32 | Thu Feb 24 | vsWilliam & Mary | W62-28 | 8-20 | .286 | - | | Matthews Arena · Boston, MA |
| 33 | Sat Feb 26 | vsElon | L54-67 | 8-21 | .276 | - | CBS | Matthews Arena · Boston, MA |
| 34 | Sat Mar 5 | atWilliam & Mary | W68-63 (OT) | 9-21 | .300 | - | | Kaplan Arena · Williamsburg, VA |
| 35 | Sun Mar 6 | atTowson | L61-68 | 9-22 | .290 | - | | SECU Arena · Towson, MD |
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