| 1 | Wed Nov 6 | vs N'Western St | W77-63 | 1-0 | 1.000 | - | | Reed Arena · College Station, TX |
| 2 | Mon Nov 11 | vsUL Monroe | W63-57 | 2-0 | 1.000 | - | | Reed Arena · College Station, TX |
| 3 | Fri Nov 15 | vs#8Gonzaga | L49-79 | 2-1 | .667 | - | SEC Network | Reed Arena · College Station, TX |
| 4 | Wed Nov 20 | vsTroy | W56-52 | 3-1 | .750 | - | | Reed Arena · College Station, TX |
| 5 | Thu Nov 28 | atHarvard | L51-62 | 3-2 | .600 | - | ESPN2 | Lavietes Pavilion · Cambridge, MA |
| 6 | Fri Nov 29 | vsTemple | L42-65 | 3-3 | .500 | - | ESPNEWS | Reed Arena · College Station, TX |
| 7 | Sun Dec 1 | atFairfield | L62-67 | 3-4 | .429 | - | ESPNU | Leo D. Mahoney Arena · Fairfield, CT |
| 8 | Sun Dec 8 | atTexas | L50-60 | 3-5 | .375 | - | ABC | Moody Center · Austin, TX |
| 9 | Sun Dec 15 | vsTexas A&M-CC | W63-60 | 4-5 | .444 | - | | Reed Arena · College Station, TX |
| 10 | Sat Dec 21 | vsOregon St | W64-49 | 5-5 | .500 | - | SEC Network | Reed Arena · College Station, TX |
| 11 | Mon Dec 30 | vsTexas So | W58-55 | 6-5 | .545 | - | | Reed Arena · College Station, TX |
| 12 | Sat Jan 4 | atArkansas | L59-69 | 6-6 | .500 | - | SEC Network | Bud Walton Arena · Fayetteville, AR |
| 13 | Tue Jan 7 | vsOle Miss | W57-47 | 7-6 | .538 | - | SEC Network | Reed Arena · College Station, TX |
| 14 | Sat Jan 11 | atVanderbilt | W69-50 | 8-6 | .571 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 15 | Tue Jan 14 | vsLSU | L85-89 (OT) | 8-7 | .533 | - | SEC Network | Reed Arena · College Station, TX |
| 16 | Sat Jan 18 | vsSouth Carolina | L67-81 | 8-8 | .500 | - | SEC Network | Reed Arena · College Station, TX |
| 17 | Tue Jan 21 | atMissouri | W66-64 | 9-8 | .529 | - | ESPNU | Mizzou Arena · Columbia, MO |
| 18 | Sat Jan 25 | vsOklahoma St | L62-73 | 9-9 | .500 | - | ESPNU | Reed Arena · College Station, TX |
| 19 | Tue Jan 28 | atTennessee | W63-58 | 10-9 | .526 | - | SEC Network | Thompson-Boling Arena · Knoxville, TN |
| 20 | Sat Feb 1 | atGeorgia | L48-63 | 10-10 | .500 | - | SEC Network | Stegeman Coliseum · Athens, GA |
| 21 | Tue Feb 4 | vsMissouri | W68-51 | 11-10 | .524 | - | SEC Network | Reed Arena · College Station, TX |
| 22 | Sat Feb 8 | atSouth Carolina | L54-74 | 11-11 | .500 | - | SEC Network | Colonial Life Arena · Columbia, SC |
| 23 | Wed Feb 12 | vsFlorida | L61-78 | 11-12 | .478 | - | SEC Network | Reed Arena · College Station, TX |
| 24 | Sat Feb 15 | vsGeorgia | W74-69 | 12-12 | .500 | - | SEC Network | Reed Arena · College Station, TX |
| 25 | Wed Feb 19 | atAlabama | W74-68 | 13-12 | .520 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 26 | Sat Feb 22 | vsMississippi St | W87-75 | 14-12 | .538 | - | SEC Network | Reed Arena · College Station, TX |
| 27 | Tue Feb 25 | vs#8Kentucky | L60-69 | 14-13 | .519 | - | ESPN | Reed Arena · College Station, TX |
| 28 | Sat Feb 29 | atLSU | L50-64 | 14-14 | .500 | - | ESPN2 | Pete Maravich Assembly Center · Baton Rouge, LA |
| 29 | Wed Mar 4 | at#17Auburn | W78-75 | 15-14 | .517 | - | ESPN2 | Neville Arena · Auburn, AL |
| 30 | Sat Mar 7 | vsArkansas | W77-69 | 16-14 | .533 | - | SEC Network | Reed Arena · College Station, TX |
