| 1 | Mon Nov 7 | at San Francisco | L77-90 | 0-1 | .000 | - | | War Memorial at the Sobrato Center · San Francisco, CA |
| 2 | Thu Nov 10 | at #25Texas Tech | L54-78 | 0-2 | .000 | - | | United Supermarkets Arena · Lubbock, TX |
| 3 | Sun Nov 13 | vs Arizona St | W67-66 (OT) | 1-2 | .333 | - | | H&PE Arena · Houston, TX |
| 4 | Tue Nov 15 | vs Oral Roberts | L64-82 | 1-3 | .250 | - | | H&PE Arena · Houston, TX |
| 5 | Wed Nov 16 | at Houston | L48-83 | 1-4 | .200 | - | | Fertitta Center · Houston, TX |
| 6 | Fri Nov 18 | at #13Auburn | L56-72 | 1-5 | .167 | - | | Neville Arena · Auburn, AL |
| 7 | Sun Nov 20 | at Samford | L63-78 | 1-6 | .143 | - | | Pete Hanna Center · Homewood, AL |
| 8 | Mon Nov 28 | at #9Kansas | L55-87 | 1-7 | .125 | - | | Allen Fieldhouse · Lawrence, KS |
| 9 | Sun Dec 11 | vs TBD | W95-47 | 2-7 | .222 | - | | H&PE Arena · Houston, TX |
| 10 | Sat Dec 17 | at NC A&T | L66-67 (OT) | 2-8 | .200 | - | | Corbett Sports Center · Greensboro, NC |
| 11 | Sun Dec 18 | at Hampton | W82-77 | 3-8 | .273 | - | ESPNU | Convocation Center (VA) · Hampton, VA |
| 12 | Thu Dec 22 | at Wichita St | L56-65 | 3-9 | .250 | - | | Charles Koch Arena · Wichita, KS |
| 13 | Thu Dec 29 | vsTBD | W92-54 | 4-9 | .308 | - | | H&PE Arena · Houston, TX |
| 14 | Mon Jan 2 | vs Southern | L76-77 (OT) | 4-10 | .286 | - | | H&PE Arena · Houston, TX |
| 15 | Wed Jan 4 | vs Grambling | L72-85 | 4-11 | .267 | - | | H&PE Arena · Houston, TX |
| 16 | Sat Jan 7 | at AR-Pine Bluff | L66-70 | 4-12 | .250 | - | | H. O. Clemmons Arena · Pine Bluff, AR |
| 17 | Mon Jan 9 | at Miss Valley St | L67-71 | 4-13 | .235 | - | | Robert W. Harrison HPER Complex · Itta Bena, MS |
| 18 | Sat Jan 14 | vs Alcorn St | L74-79 (OT) | 4-14 | .222 | - | | H&PE Arena · Houston, TX |
| 19 | Mon Jan 16 | vs Jackson St | W84-82 | 5-14 | .263 | - | | H&PE Arena · Houston, TX |
| 20 | Sat Jan 21 | at Alabama A&M | W70-59 | 6-14 | .300 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 21 | Mon Jan 23 | at Alabama St | W71-65 | 7-14 | .333 | - | | Dunn-Oliver Acadome · Montgomery, AL |
| 22 | Sat Jan 28 | vs Prairie View | L74-89 (2OT) | 7-15 | .318 | - | | H&PE Arena · Houston, TX |
| 23 | Sat Feb 4 | vs FAMU | L69-76 | 7-16 | .304 | - | | H&PE Arena · Houston, TX |
| 24 | Mon Feb 6 | vs Bethune | W69-62 | 8-16 | .333 | - | ESPNU | H&PE Arena · Houston, TX |
| 25 | Sat Feb 11 | atGrambling | L46-65 | 8-17 | .320 | - | | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 26 | Mon Feb 13 | atSouthern | W79-68 | 9-17 | .346 | - | | F. G. Clark Activity Center · Baton Rouge, LA |
| 27 | Sat Feb 18 | vsMiss Valley St | W80-62 | 10-17 | .370 | - | | H&PE Arena · Houston, TX |
| 28 | Mon Feb 20 | vsAR-Pine Bluff | W64-59 | 11-17 | .393 | - | | H&PE Arena · Houston, TX |
| 29 | Sat Feb 25 | atJackson St | L69-71 | 11-18 | .379 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 30 | Mon Feb 27 | atAlcorn St | L81-89 | 11-19 | .367 | - | | Davey L. Whitney Complex · Lorman, MS |
| 31 | Sat Mar 4 | atPrairie View | L74-78 | 11-20 | .355 | - | | William Nicks Building · Prairie View, TX |
| 32 | Wed Mar 8 | atAlcorn St | W66-62 | 12-20 | .375 | - | | Davey L. Whitney Complex · Lorman, MS |
| 33 | Fri Mar 10 | atAlabama A&M | W74-61 | 13-20 | .394 | - | | T.M. Elmore Gymnasium · Normal, AL |
| 34 | Sat Mar 11 | atGrambling | W61-58 | 14-20 | .412 | - | ESPNU | Fredrick C. Hobdy Assembly Center · Grambling, LA |
| 35 | Wed Mar 15 | vs #16Fairleigh | L61-84 | 14-21 | .400 | #16 | truTV | H&PE Arena · Houston, TX |
