| 1 | Wed Nov 25 | vs TBD | W89-64 | 1-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 2 | Thu Dec 3 | vsNC A&T | W78-70 | 2-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 3 | Sat Dec 5 | vsTBD | W100-58 | 3-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 4 | Mon Dec 7 | vsTBD | W96-57 | 4-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 5 | Wed Dec 9 | vsTBD | W102-51 | 5-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 6 | Sat Dec 19 | atLongwood | W91-89 | 6-0 | 1.000 | - | | Willett Hall · Farmville, VA |
| 7 | Tue Dec 22 | vsPresbyterian | W94-82 | 7-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 8 | Sat Jan 9 | vsChattanooga | W92-87 | 8-0 | 1.000 | - | | McAlister Field House · Charleston, SC |
| 9 | Wed Jan 13 | vsFurman | L88-94 | 8-1 | .889 | - | | McAlister Field House · Charleston, SC |
| 10 | Sat Jan 16 | atVMI | L103-110 | 8-2 | .800 | - | | Cameron Hall · Lexington, VA |
| 11 | Mon Jan 18 | atUNC Greensboro | L73-87 | 8-3 | .727 | - | | Greensboro Coliseum · Greensboro, NC |
| 12 | Wed Jan 20 | vsMercer | L63-83 | 8-4 | .667 | - | | McAlister Field House · Charleston, SC |
| 14 | Wed Jan 27 | vsWofford | W77-69 | 9-4 | .692 | - | | McAlister Field House · Charleston, SC |
| 15 | Sat Jan 30 | atETSU | L84-112 | 9-5 | .643 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 16 | Mon Feb 1 | atW Carolina | L75-76 | 9-6 | .600 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 17 | Wed Feb 3 | vsUNC Greensboro | L66-85 | 9-7 | .563 | - | | McAlister Field House · Charleston, SC |
| 18 | Sat Feb 6 | vsW Carolina | W74-63 | 10-7 | .588 | - | | McAlister Field House · Charleston, SC |
| 19 | Wed Feb 10 | vsETSU | W79-71 | 11-7 | .611 | - | | McAlister Field House · Charleston, SC |
| 20 | Sat Feb 13 | atChattanooga | L66-70 | 11-8 | .579 | - | | McKenzie Arena · Chattanooga, TN |
| 21 | Wed Feb 17 | atWofford | L67-81 | 11-9 | .550 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 22 | Sat Feb 20 | vsVMI | W75-74 | 12-9 | .571 | - | | McAlister Field House · Charleston, SC |
| 23 | Mon Feb 22 | atMercer | L52-88 | 12-10 | .545 | - | | Hawkins Arena · Macon, GA |
| 24 | Wed Feb 24 | atFurman | L63-72 | 12-11 | .522 | - | | Timmons Arena · Greenville, SC |
| 26 | Fri Mar 5 | vsW Carolina | W100-86 | 13-11 | .542 | - | | McAlister Field House · Charleston, SC |
| 27 | Sat Mar 6 | atUNC Greensboro | L72-80 | 13-12 | .520 | - | | Greensboro Coliseum · Greensboro, NC |
