| 1 | Mon Nov 3 | vs TBD | 7:00 PM | 0-0 | .000 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 2 | Thu Nov 6 | atBoston College | TBD | 12-19 | .387 | - | | Silvio O. Conte Forum · Chestnut Hill, MA |
| 3 | Mon Nov 10 | vsCharleston So | 7:00 PM | 10-22 | .313 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 4 | Fri Nov 14 | atW Georgia | 7:00 PM | 6-25 | .194 | - | ESPN+ | The Coliseum · Carrollton, GA |
| 5 | Wed Nov 19 | vsTBD | 7:00 PM | 0-0 | .000 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 6 | Mon Nov 24 | vsBellarmine | 7:00 PM | 5-26 | .161 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 7 | Wed Nov 26 | vsHou Christian | 7:00 PM | 12-20 | .375 | - | ESPN+ | McAlister Field House · Charleston, SC |
| 8 | Sun Nov 30 | atPresbyterian | 4:00 PM | 14-19 | .424 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 9 | Thu Dec 4 | atDavidson | TBD | 17-16 | .515 | - | | John M. Belk Arena · Davidson, NC |
| 10 | Tue Dec 9 | vsTBD | 7:00 PM | 0-0 | .000 | - | | McAlister Field House · Charleston, SC |
| 11 | Sat Dec 13 | atSouth Carolina | 7:00 PM | 12-20 | .375 | - | | Colonial Life Arena · Columbia, SC |
| 12 | Wed Dec 17 | atCharleston | 7:00 PM | 24-9 | .727 | - | | TD Arena · Charleston, SC |
| 13 | Sat Dec 20 | atRichmond | TBD | 10-22 | .313 | - | | Robins Center · Richmond, VA |
| 14 | Wed Dec 31 | vsETSU | TBD | 19-13 | .594 | - | | McAlister Field House · Charleston, SC |
| 15 | Sat Jan 3 | vsWofford | TBD | 19-16 | .543 | - | | McAlister Field House · Charleston, SC |
| 16 | Wed Jan 7 | atMercer | TBD | 14-19 | .424 | - | | Hawkins Arena · Macon, GA |
| 17 | Sat Jan 10 | vsW Carolina | TBD | 8-22 | .267 | - | | McAlister Field House · Charleston, SC |
| 18 | Thu Jan 15 | atUNC Greensboro | TBD | 20-12 | .625 | - | | Greensboro Coliseum · Greensboro, NC |
| 19 | Sat Jan 17 | atVMI | TBD | 15-19 | .441 | - | | Cameron Hall · Lexington, VA |
| 20 | Wed Jan 21 | vsFurman | TBD | 25-10 | .714 | - | | McAlister Field House · Charleston, SC |
| 21 | Sat Jan 24 | atETSU | TBD | 19-13 | .594 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 22 | Thu Jan 29 | vsVMI | TBD | 15-19 | .441 | - | | McAlister Field House · Charleston, SC |
| 23 | Sat Jan 31 | vsUNC Greensboro | TBD | 20-12 | .625 | - | | McAlister Field House · Charleston, SC |
| 24 | Thu Feb 5 | atSamford | TBD | 22-11 | .667 | - | | Pete Hanna Center · Homewood, AL |
| 25 | Sat Feb 7 | atChattanooga | TBD | 29-9 | .763 | - | | McKenzie Arena · Chattanooga, TN |
| 26 | Wed Feb 11 | atW Carolina | TBD | 8-22 | .267 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 27 | Sat Feb 14 | vsMercer | TBD | 14-19 | .424 | - | | McAlister Field House · Charleston, SC |
| 28 | Thu Feb 19 | vsSamford | TBD | 22-11 | .667 | - | | McAlister Field House · Charleston, SC |
| 29 | Sat Feb 21 | vsChattanooga | TBD | 29-9 | .763 | - | | McAlister Field House · Charleston, SC |
| 30 | Wed Feb 25 | atFurman | TBD | 25-10 | .714 | - | | Timmons Arena · Greenville, SC |
| 31 | Sat Feb 28 | atWofford | TBD | 19-16 | .543 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
