| 1 | Tue Nov 9 | vs NC A&T | W57-53 | 1-0 | 1.000 | - | | Greensboro Coliseum · Greensboro, NC |
| 2 | Fri Nov 12 | atN Kentucky | W70-69 (OT) | 2-0 | 1.000 | - | | Truist Arena · Highland Heights, KY |
| 3 | Mon Nov 15 | vsCoppin St | W55-48 | 3-0 | 1.000 | - | | Greensboro Coliseum · Greensboro, NC |
| 4 | Thu Nov 18 | vsGreen Bay | W60-58 | 4-0 | 1.000 | - | CBS | Greensboro Coliseum · Greensboro, NC |
| 5 | Fri Nov 19 | atUMass | L90-93 (OT) | 4-1 | .800 | - | CBS | William D. Mullins Memorial Center · Amherst, MA |
| 6 | Sun Nov 21 | atFIU | L71-74 (OT) | 4-2 | .667 | - | | Ocean Bank Convocation Center · Miami, FL |
| 7 | Wed Nov 24 | vsTBD | W80-61 | 5-2 | .714 | - | | Greensboro Coliseum · Greensboro, NC |
| 8 | Sat Nov 27 | vsVermont | W54-51 | 6-2 | .750 | - | | Greensboro Coliseum · Greensboro, NC |
| 9 | Tue Nov 30 | vsElon | W74-61 | 7-2 | .778 | - | | Greensboro Coliseum · Greensboro, NC |
| 10 | Sat Dec 11 | at#13Tennessee | L36-76 | 7-3 | .700 | - | SEC Network | Thompson-Boling Arena · Knoxville, TN |
| 11 | Tue Dec 14 | atTowson | L64-74 | 7-4 | .636 | - | | SECU Arena · Towson, MD |
| 12 | Thu Dec 16 | atUMBC | W62-51 | 8-4 | .667 | - | | Chesapeake Employers Insurance Arena · Baltimore, MD |
| 14 | Wed Dec 29 | atW Carolina | PPD | 17-15 | .531 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 15 | Sat Jan 1 | vsWofford | PPD | 17-15 | .531 | - | | Greensboro Coliseum · Greensboro, NC |
| 16 | Wed Jan 5 | vsFurman | L54-58 | 8-5 | .615 | - | ESPNEWS | Greensboro Coliseum · Greensboro, NC |
| 17 | Sat Jan 8 | atVMI | W72-56 | 9-5 | .643 | - | | Cameron Hall · Lexington, VA |
| 18 | Mon Jan 10 | vsWofford | W58-54 | 10-5 | .667 | - | | Greensboro Coliseum · Greensboro, NC |
| 19 | Thu Jan 13 | atThe Citadel | L69-74 | 10-6 | .625 | - | | McAlister Field House · Charleston, SC |
| 20 | Sat Jan 15 | atMercer | L49-58 | 10-7 | .588 | - | | Hawkins Arena · Macon, GA |
| 21 | Thu Jan 20 | vsChattanooga | L64-72 | 10-8 | .556 | - | | Greensboro Coliseum · Greensboro, NC |
| 22 | Sat Jan 22 | vsSamford | W61-58 | 11-8 | .579 | - | | Greensboro Coliseum · Greensboro, NC |
| 23 | Wed Jan 26 | atETSU | W80-76 | 12-8 | .600 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 24 | Sat Jan 29 | atWofford | L66-85 | 12-9 | .571 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 25 | Wed Feb 2 | vsVMI | L65-76 | 12-10 | .545 | - | | Greensboro Coliseum · Greensboro, NC |
| 26 | Sat Feb 5 | atFurman | W58-56 | 13-10 | .565 | - | | Timmons Arena · Greenville, SC |
| 27 | Mon Feb 7 | atW Carolina | W68-49 | 14-10 | .583 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 28 | Thu Feb 10 | vsThe Citadel | W86-66 | 15-10 | .600 | - | | Greensboro Coliseum · Greensboro, NC |
| 29 | Sun Feb 13 | vsMercer | L64-73 | 15-11 | .577 | - | | Greensboro Coliseum · Greensboro, NC |
| 30 | Thu Feb 17 | atChattanooga | W73-70 | 16-11 | .593 | - | | McKenzie Arena · Chattanooga, TN |
| 31 | Sat Feb 19 | atSamford | L49-55 | 16-12 | .571 | - | | Pete Hanna Center · Homewood, AL |
| 32 | Wed Feb 23 | vsW Carolina | W73-64 | 17-12 | .586 | - | | Greensboro Coliseum · Greensboro, NC |
| 33 | Sun Feb 27 | vsETSU | L69-73 | 17-13 | .567 | - | | Greensboro Coliseum · Greensboro, NC |
| 34 | Sat Mar 5 | atSamford | L64-66 | 17-14 | .548 | - | | Pete Hanna Center · Homewood, AL |
| 35 | Sun Mar 20 | atBoston Univ | L68-71 | 17-15 | .531 | - | | Case Gym · Boston, MA |
