| 1 | Tue Nov 5 | vs TBD | W103-83 | 1-0 | 1.000 | - | | Trask Coliseum · Wilmington, NC |
| 2 | Fri Nov 8 | vs #9UNC | L62-78 | 1-1 | .500 | - | | Trask Coliseum · Wilmington, NC |
| 3 | Tue Nov 12 | vs Campbell | W81-76 (OT) | 2-1 | .667 | - | | Trask Coliseum · Wilmington, NC |
| 4 | Sat Nov 16 | at Davidson | L49-87 | 2-2 | .500 | - | | John M. Belk Arena · Davidson, NC |
| 5 | Tue Nov 19 | vsTBD | W113-53 | 3-2 | .600 | - | | Trask Coliseum · Wilmington, NC |
| 6 | Fri Nov 22 | vs Cleveland St | L46-47 | 3-3 | .500 | - | | Trask Coliseum · Wilmington, NC |
| 7 | Sat Nov 23 | at FIU | W66-63 | 4-3 | .571 | - | | Ocean Bank Convocation Center · Miami, FL |
| 8 | Tue Nov 26 | vsTBD | W122-66 | 5-3 | .625 | - | | Trask Coliseum · Wilmington, NC |
| 9 | Fri Nov 29 | at Boise St | L59-80 | 5-4 | .556 | - | | ExtraMile Arena · Boise, ID |
| 10 | Sun Dec 1 | at Stanford | L54-72 | 5-5 | .500 | - | PACN | Maples Pavilion · Stanford, CA |
| 11 | Sat Dec 7 | vs Charlotte | L57-76 | 5-6 | .455 | - | | Trask Coliseum · Wilmington, NC |
| 12 | Mon Dec 16 | vs Mercer | L63-72 | 5-7 | .417 | - | | Trask Coliseum · Wilmington, NC |
| 13 | Sat Dec 21 | at Vanderbilt | L73-88 | 5-8 | .385 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 14 | Sat Dec 28 | at Delaware | L68-82 | 5-9 | .357 | - | | Bob Carpenter Center · Newark, DE |
| 15 | Mon Dec 30 | at Drexel | L66-71 | 5-10 | .333 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 16 | Thu Jan 2 | vs JMU | L60-64 | 5-11 | .313 | - | CBS | Trask Coliseum · Wilmington, NC |
| 17 | Sat Jan 4 | vs Towson | L60-67 | 5-12 | .294 | - | | Trask Coliseum · Wilmington, NC |
| 18 | Thu Jan 9 | at William & Mary | L63-79 | 5-13 | .278 | - | | Kaplan Arena · Williamsburg, VA |
| 19 | Sat Jan 11 | at Elon | L63-80 | 5-14 | .263 | - | | Schar Center · Elon, NC |
| 20 | Thu Jan 16 | vs Hofstra | L61-63 | 5-15 | .250 | - | | Trask Coliseum · Wilmington, NC |
| 21 | Sat Jan 18 | vs Northeastern | W76-74 (OT) | 6-15 | .286 | - | | Trask Coliseum · Wilmington, NC |
| 22 | Sat Jan 25 | at Charleston | W72-70 | 7-15 | .318 | - | | TD Arena · Charleston, SC |
| 23 | Thu Jan 30 | atTowson | L66-77 | 7-16 | .304 | - | | SECU Arena · Towson, MD |
| 24 | Sat Feb 1 | atJMU | L66-83 | 7-17 | .292 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 25 | Thu Feb 6 | vsElon | L56-62 | 7-18 | .280 | - | | Trask Coliseum · Wilmington, NC |
| 26 | Sat Feb 8 | vsWilliam & Mary | W70-64 | 8-18 | .308 | - | | Trask Coliseum · Wilmington, NC |
| 27 | Thu Feb 13 | atNortheastern | L63-71 | 8-19 | .296 | - | | Matthews Arena · Boston, MA |
| 28 | Sat Feb 15 | atHofstra | L64-78 | 8-20 | .286 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 29 | Sat Feb 22 | vsCharleston | W68-55 | 9-20 | .310 | - | | Trask Coliseum · Wilmington, NC |
| 30 | Thu Feb 27 | vsDrexel | W76-65 | 10-20 | .333 | - | | Trask Coliseum · Wilmington, NC |
| 31 | Sat Feb 29 | vsDelaware | L65-82 | 10-21 | .323 | - | | Trask Coliseum · Wilmington, NC |
| 32 | Sat Mar 7 | atDrexel | L55-66 | 10-22 | .313 | - | | Daskalakis Athletic Center · Philadelphia, PA |
