| 1 | Mon Nov 3 | vs TBD | 7:00 PM | 0-0 | .000 | - | | Trask Coliseum · Wilmington, NC |
| 2 | Mon Nov 10 | atKent State | 7:00 PM | 24-12 | .667 | - | ESPN+ | M.A.C. Center · Kent, OH |
| 3 | Sat Nov 15 | vsSC Upstate | TBD | 6-26 | .188 | - | | Trask Coliseum · Wilmington, NC |
| 4 | Tue Nov 18 | vsE Carolina | TBD | 19-14 | .576 | - | | Trask Coliseum · Wilmington, NC |
| 5 | Fri Nov 21 | atRadford | TBD | 20-13 | .606 | - | ESPN+ | Donald N. Dedmon Center · Radford, VA |
| 6 | Wed Nov 26 | vsSE Louisiana | TBD | 18-14 | .563 | - | | Trask Coliseum · Wilmington, NC |
| 7 | Fri Nov 28 | vsNavy | TBD | 15-19 | .441 | - | | Trask Coliseum · Wilmington, NC |
| 8 | Sat Nov 29 | vsGardner-Webb | TBD | 11-20 | .355 | - | | Trask Coliseum · Wilmington, NC |
| 9 | Wed Dec 3 | vsMarshall | 7:00 PM | 20-13 | .606 | - | | Trask Coliseum · Wilmington, NC |
| 10 | Sat Dec 6 | atLouisiana | TBD | 12-21 | .364 | - | | Cajundome · Lafayette, LA |
| 11 | Sat Dec 13 | atValparaiso | 3:00 PM | 15-19 | .441 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 12 | Sat Dec 20 | vsHoward | 2:00 PM | 12-20 | .375 | - | | Trask Coliseum · Wilmington, NC |
| 13 | Sat Dec 27 | vsTBD | TBD | 0-0 | .000 | - | | Trask Coliseum · Wilmington, NC |
| 14 | Mon Dec 29 | atNC A&T | 7:00 PM | 7-25 | .219 | - | CBS | Corbett Sports Center · Greensboro, NC |
| 15 | Wed Dec 31 | vsDrexel | 2:00 PM | 18-15 | .545 | - | CBS | Trask Coliseum · Wilmington, NC |
| 16 | Sat Jan 3 | vsHampton | TBD | 17-16 | .515 | - | | Trask Coliseum · Wilmington, NC |
| 17 | Thu Jan 8 | atNortheastern | TBD | 17-15 | .531 | - | | Matthews Arena · Boston, MA |
| 18 | Sat Jan 10 | atStony Brook | TBD | 8-24 | .250 | - | | Island FCU Arena · Stony Brook, NY |
| 19 | Sat Jan 17 | vsCampbell | TBD | 15-17 | .469 | - | | Trask Coliseum · Wilmington, NC |
| 20 | Thu Jan 22 | atWilliam & Mary | TBD | 17-15 | .531 | - | | Kaplan Arena · Williamsburg, VA |
| 21 | Sat Jan 24 | atHampton | 2:30 PM | 17-16 | .515 | - | | Convocation Center (VA) · Hampton, VA |
| 22 | Thu Jan 29 | atTowson | 9:00 PM | 22-11 | .667 | - | CBS | SECU Arena · Towson, MD |
| 23 | Thu Feb 5 | vsWilliam & Mary | 7:00 PM | 17-15 | .531 | - | CBS | Trask Coliseum · Wilmington, NC |
| 24 | Mon Feb 9 | atCharleston | 8:00 PM | 24-9 | .727 | - | CBS | TD Arena · Charleston, SC |
| 25 | Thu Feb 12 | vsElon | TBD | 17-16 | .515 | - | | Trask Coliseum · Wilmington, NC |
| 26 | Sat Feb 14 | vsHofstra | 4:00 PM | 15-18 | .455 | - | CBS | Trask Coliseum · Wilmington, NC |
| 27 | Thu Feb 19 | vsMonmouth | TBD | 13-20 | .394 | - | | Trask Coliseum · Wilmington, NC |
| 28 | Sat Feb 21 | atCampbell | TBD | 15-17 | .469 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 29 | Thu Feb 26 | vsNC A&T | TBD | 7-25 | .219 | - | | Trask Coliseum · Wilmington, NC |
| 30 | Sun Mar 1 | vsCharleston | 7:00 PM | 24-9 | .727 | - | CBS | Trask Coliseum · Wilmington, NC |
| 31 | Tue Mar 3 | atElon | TBD | 17-16 | .515 | - | | Schar Center · Elon, NC |
