| 1 | Mon Nov 7 | vs Weber St | W69-52 | 1-0 | 1.000 | - | | Alaska Airlines Arena · Seattle, WA |
| 2 | Fri Nov 11 | vs North Florida | W75-67 | 2-0 | 1.000 | - | | Alaska Airlines Arena · Seattle, WA |
| 3 | Mon Nov 14 | vs Utah Tech | W78-67 | 3-0 | 1.000 | - | | Alaska Airlines Arena · Seattle, WA |
| 4 | Thu Nov 17 | vs CA Baptist | L64-73 | 3-1 | .750 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 5 | Wed Nov 23 | vs Fresno St | W62-57 | 4-1 | .800 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 6 | Fri Nov 25 | at Saint Mary's | W68-64 (OT) | 5-1 | .833 | - | ESPN2 | University Credit Union Pavilion · Moraga, CA |
| 7 | Mon Nov 28 | vs Seattle U | W77-66 | 6-1 | .857 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 8 | Thu Dec 1 | at Oregon St | L65-66 | 6-2 | .750 | - | ESPNU | Gill Coliseum · Corvallis, OR |
| 9 | Sun Dec 4 | vs Colorado | W73-63 | 7-2 | .778 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 10 | Fri Dec 9 | at #18Gonzaga | L60-77 | 7-3 | .700 | - | | McCarthey Athletic Center · Spokane, WA |
| 11 | Tue Dec 13 | vs Cal Poly | W74-68 | 8-3 | .727 | - | | Alaska Airlines Arena · Seattle, WA |
| 12 | Sat Dec 17 | vs Idaho St | W90-55 | 9-3 | .750 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 13 | Wed Dec 21 | vs #23Auburn | L61-84 | 9-4 | .692 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 14 | Fri Dec 30 | vs USC | L67-80 | 9-5 | .643 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 15 | Sun Jan 1 | vs #11UCLA | L49-74 | 9-6 | .600 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 16 | Thu Jan 5 | at #5Arizona | L67-70 | 9-7 | .563 | - | FS1 | McKale Center · Tucson, AZ |
| 17 | Sun Jan 8 | at Arizona St | L65-73 | 9-8 | .529 | - | ESPN | Desert Financial Arena · Tempe, AZ |
| 18 | Thu Jan 12 | vs Stanford | W86-69 | 10-8 | .556 | - | FS1 | Alaska Airlines Arena · Seattle, WA |
| 19 | Sat Jan 14 | vs California | W81-78 (OT) | 11-8 | .579 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 20 | Thu Jan 19 | atColorado | W75-72 | 12-8 | .600 | - | ESPNU | CU Events Center · Boulder, CO |
| 21 | Sat Jan 21 | at Utah | L61-86 | 12-9 | .571 | - | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 22 | Thu Jan 26 | vsArizona St | W69-66 (OT) | 13-9 | .591 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 23 | Sat Jan 28 | vs#6Arizona | L72-95 | 13-10 | .565 | - | FOX | Alaska Airlines Arena · Seattle, WA |
| 24 | Thu Feb 2 | at#9UCLA | L61-70 | 13-11 | .542 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 25 | Sat Feb 4 | atUSC | L74-80 | 13-12 | .520 | - | FS1 | Galen Center · Los Angeles, CA |
| 26 | Sat Feb 11 | at Washington St | L51-56 | 13-13 | .500 | - | PACN | Friel Court at Beasley Coliseum · Pullman, WA |
| 27 | Wed Feb 15 | vs Oregon | W72-71 (OT) | 14-13 | .519 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 28 | Sat Feb 18 | vsOregon St | W61-47 | 15-13 | .536 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 29 | Thu Feb 23 | atCalifornia | W65-56 | 16-13 | .552 | - | PACN | Haas Pavilion · Berkeley, CA |
| 30 | Sun Feb 26 | atStanford | L69-81 | 16-14 | .533 | - | FS1 | Maples Pavilion · Stanford, CA |
| 31 | Thu Mar 2 | vsWashington St | L84-93 | 16-15 | .516 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 32 | Wed Mar 8 | vsColorado | L68-74 | 16-16 | .500 | - | PACN | Alaska Airlines Arena · Seattle, WA |
