| 1 | Tue Nov 9 | vs N Illinois | L64-71 | 0-1 | .000 | - | | Alaska Airlines Arena · Seattle, WA |
| 2 | Thu Nov 11 | vsN Arizona | W73-62 | 1-1 | .500 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 3 | Mon Nov 15 | vsTexas So | W72-65 | 2-1 | .667 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 4 | Thu Nov 18 | vsWyoming | L72-77 (OT) | 2-2 | .500 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 5 | Mon Nov 22 | vsGeorge Mason | W77-74 | 3-2 | .600 | - | | Alaska Airlines Arena · Seattle, WA |
| 6 | Tue Nov 23 | atS Dakota St | W87-76 | 4-2 | .667 | - | | Frost Arena · Brookings, SD |
| 7 | Wed Nov 24 | vsNevada | L62-81 | 4-3 | .571 | - | | Alaska Airlines Arena · Seattle, WA |
| 8 | Sat Nov 27 | vsWinthrop | L74-82 | 4-4 | .500 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 9 | Thu Dec 2 | at11Arizona | PPD | 17-15 | .531 | - | | McKale Center · Tucson, AZ |
| 10 | Sun Dec 5 | vs5UCLA | PPD | 4-4 | .500 | - | | Alaska Airlines Arena · Seattle, WA |
| 12 | Sat Dec 18 | vsSeattle U | W64-56 | 5-4 | .556 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 13 | Tue Dec 21 | vsUtah Valley | L52-68 | 5-5 | .500 | - | | Alaska Airlines Arena · Seattle, WA |
| 14 | Wed Dec 29 | atWashington St | PPD | 17-15 | .531 | - | | Friel Court at Beasley Coliseum · Pullman, WA |
| 15 | Mon Jan 3 | at8Arizona | L79-95 | 5-6 | .455 | - | PACN | McKale Center · Tucson, AZ |
| 16 | Thu Jan 6 | atUtah | W74-68 | 6-6 | .500 | - | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 17 | Sun Jan 9 | atColorado | L64-78 | 6-7 | .462 | - | ESPN2 | CU Events Center · Boulder, CO |
| 18 | Wed Jan 12 | vsCalifornia | W64-55 | 7-7 | .500 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 19 | Sat Jan 15 | vsStanford | W67-64 | 8-7 | .533 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 20 | Thu Jan 20 | atOregon St | W82-72 | 9-7 | .563 | - | PACN | Gill Coliseum · Corvallis, OR |
| 21 | Sun Jan 23 | atOregon | L56-84 | 9-8 | .529 | - | | Matthew Knight Arena · Eugene, OR |
| 22 | Thu Jan 27 | vsColorado | W60-58 | 10-8 | .556 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 23 | Sat Jan 29 | vsUtah | W77-73 (2OT) | 11-8 | .579 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 24 | Thu Feb 3 | atCalifornia | W84-63 | 12-8 | .600 | - | PACN | Haas Pavilion · Berkeley, CA |
| 25 | Sun Feb 6 | atStanford | L69-87 | 12-9 | .571 | - | ESPNU | Maples Pavilion · Stanford, CA |
| 26 | Thu Feb 10 | vsArizona St | W87-64 | 13-9 | .591 | - | FS1 | Alaska Airlines Arena · Seattle, WA |
| 27 | Sat Feb 12 | vs4Arizona | L68-92 | 13-10 | .565 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 28 | Thu Feb 17 | at17USC | L69-79 | 13-11 | .542 | - | PACN | Galen Center · Los Angeles, CA |
| 29 | Sat Feb 19 | at13UCLA | L50-76 | 13-12 | .520 | - | FS1 | Pauley Pavilion · Los Angeles, CA |
| 30 | Wed Feb 23 | atWashington St | L70-78 | 13-13 | .500 | - | ESPNU | Friel Court at Beasley Coliseum · Pullman, WA |
| 31 | Sat Feb 26 | vsWashington St | W78-70 | 14-13 | .519 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 32 | Mon Feb 28 | vs17UCLA | L66-77 | 14-14 | .500 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 33 | Thu Mar 3 | vsOregon | W78-67 | 15-14 | .517 | - | | Alaska Airlines Arena · Seattle, WA |
| 34 | Sat Mar 5 | vsOregon St | W78-67 | 16-14 | .533 | - | | Alaska Airlines Arena · Seattle, WA |
| 35 | Wed Mar 9 | vsUtah | W82-70 | 17-14 | .548 | - | PACN | T-Mobile Arena · Las Vegas, NV |
| 36 | Thu Mar 10 | atUSC | L61-65 | 17-15 | .531 | - | FS1 | T-Mobile Arena · Las Vegas, NV |
