| 1 | Mon Nov 6 | vs Bellarmine | W91-57 | 1-0 | 1.000 | - | | Alaska Airlines Arena · Seattle, WA |
| 2 | Thu Nov 9 | vs N Kentucky | W75-67 | 2-0 | 1.000 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 3 | Sun Nov 12 | vs Nevada | L76-83 | 2-1 | .667 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 4 | Fri Nov 17 | at Xavier | W74-71 | 3-1 | .750 | - | ESPN2 | Cintas Center · Cincinnati, OH |
| 5 | Sun Nov 19 | at SDSU | L97-100 (OT) | 3-2 | .600 | - | ESPN2 | Viejas Arena · San Diego, CA |
| 6 | Tue Nov 28 | vs UC San Diego | W83-56 | 4-2 | .667 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 7 | Sat Dec 2 | at #20Colorado St | L81-86 | 4-3 | .571 | - | CBS | Moby Arena · Fort Collins, CO |
| 8 | Tue Dec 5 | vs Montana St | W85-61 | 5-3 | .625 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 9 | Sat Dec 9 | vs #7Gonzaga | W78-73 | 6-3 | .667 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 10 | Sun Dec 17 | at Seattle U | W100-99 (2OT) | 7-3 | .700 | - | | Redhawk Center · Seattle, WA |
| 11 | Thu Dec 21 | vs E Washington | W73-66 | 8-3 | .727 | - | | Alaska Airlines Arena · Seattle, WA |
| 12 | Fri Dec 29 | at Colorado | L69-73 | 8-4 | .667 | - | ESPNU | CU Events Center · Boulder, CO |
| 13 | Sun Dec 31 | at Utah | L90-95 | 8-5 | .615 | - | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 14 | Thu Jan 4 | vs Oregon | L74-76 | 8-6 | .571 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 15 | Sat Jan 6 | vs Oregon St | W79-72 | 9-6 | .600 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 16 | Thu Jan 11 | vs Arizona St | W82-67 | 10-6 | .625 | - | FS1 | Alaska Airlines Arena · Seattle, WA |
| 17 | Sun Jan 14 | at UCLA | L61-73 | 10-7 | .588 | - | PACN | Pauley Pavilion · Los Angeles, CA |
| 18 | Thu Jan 18 | at California | W77-75 | 11-7 | .611 | - | PACN | Haas Pavilion · Berkeley, CA |
| 19 | Sat Jan 20 | at Stanford | L80-90 | 11-8 | .579 | - | PACN | Maples Pavilion · Stanford, CA |
| 20 | Wed Jan 24 | vsColorado | L81-98 | 11-9 | .550 | - | ESPNU | Alaska Airlines Arena · Seattle, WA |
| 21 | Sat Jan 27 | vsUtah | W98-73 | 12-9 | .571 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 22 | Sat Feb 3 | vs Washington St | L87-90 (OT) | 12-10 | .545 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 23 | Thu Feb 8 | atOregon | L80-85 | 12-11 | .522 | - | FS1 | Matthew Knight Arena · Eugene, OR |
| 24 | Sat Feb 10 | atOregon St | W67-55 | 13-11 | .542 | - | PACN | Gill Coliseum · Corvallis, OR |
| 25 | Thu Feb 15 | vsStanford | W85-65 | 14-11 | .560 | - | ESPN2 | Alaska Airlines Arena · Seattle, WA |
| 26 | Sat Feb 17 | vsCalifornia | L80-82 | 14-12 | .538 | - | PACN | Alaska Airlines Arena · Seattle, WA |
| 27 | Thu Feb 22 | atArizona St | W84-82 (OT) | 15-12 | .556 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 28 | Sat Feb 24 | at #4Arizona | L75-91 | 15-13 | .536 | - | CBS | McKale Center · Tucson, AZ |
| 29 | Thu Feb 29 | vsUCLA | W94-77 | 16-13 | .552 | - | FS1 | Alaska Airlines Arena · Seattle, WA |
| 30 | Sat Mar 2 | vs USC | L75-82 | 16-14 | .533 | - | CBS | Alaska Airlines Arena · Seattle, WA |
| 31 | Thu Mar 7 | at#18Washington St | W74-68 | 17-14 | .548 | - | FS1 | Friel Court at Beasley Coliseum · Pullman, WA |
| 32 | Wed Mar 13 | vsUSC | L74-80 | 17-15 | .531 | - | PACN | Alaska Airlines Arena · Seattle, WA |
