| 1 | Wed Oct 13 | vs Jets | W4-1 | 1-0-0 | 2 PTS | Honda Center · Anaheim, CA |
| 2 | Fri Oct 15 | vsWild | L1-2 | 1-1-0 | 2 PTS | Honda Center · Anaheim, CA |
| 3 | Mon Oct 18 | atFlames | W3-2 (OT) | 2-1-0 | 4 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 4 | Tue Oct 19 | atOilers | L5-6 | 2-2-0 | 4 PTS | Rogers Place · Edmonton, AB |
| 5 | Thu Oct 21 | atJets | L1-5 | 2-3-0 | 4 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 6 | Sat Oct 23 | atWild | L3-4 (OT) | 2-3-1 | 5 PTS | Xcel Energy Center · St. Paul, MN |
| 7 | Tue Oct 26 | vsJets | L3-4 | 2-4-1 | 5 PTS | Honda Center · Anaheim, CA |
| 8 | Thu Oct 28 | vsSabres | L3-4 (OT) | 2-4-2 | 6 PTS | Honda Center · Anaheim, CA |
| 9 | Fri Oct 29 | atKnights | L4-5 (SO) | 2-4-3 | 7 PTS | T-Mobile Arena · Las Vegas, NV |
| 10 | Sun Oct 31 | vsCanadiens | W4-2 | 3-4-3 | 9 PTS | Honda Center · Anaheim, CA |
| 11 | Tue Nov 2 | vsDevils | W4-0 | 4-4-3 | 11 PTS | Honda Center · Anaheim, CA |
| 12 | Fri Nov 5 | vsCoyotes | W3-1 | 5-4-3 | 13 PTS | Honda Center · Anaheim, CA |
| 13 | Sun Nov 7 | vsBlues | W4-1 | 6-4-3 | 15 PTS | Honda Center · Anaheim, CA |
| 14 | Tue Nov 9 | atCanucks | W3-2 (OT) | 7-4-3 | 17 PTS | Rogers Arena · Vancouver, British Columbia |
| 15 | Thu Nov 11 | atKraken | W7-4 | 8-4-3 | 19 PTS | Climate Pledge Arena · Seattle, WA |
| 16 | Sun Nov 14 | vsCanucks | W5-1 | 9-4-3 | 21 PTS | Honda Center · Anaheim, CA |
| 17 | Tue Nov 16 | vsCapitals | W3-2 (OT) | 10-4-3 | 23 PTS | Honda Center · Anaheim, CA |
| 18 | Thu Nov 18 | vsHurricanes | L1-2 | 10-5-3 | 23 PTS | Honda Center · Anaheim, CA |
| 19 | Mon Nov 22 | atPredators | L2-3 | 10-6-3 | 23 PTS | Bridgestone Arena · Nashville, TN |
| 20 | Wed Nov 24 | atAvalanche | L2-5 | 10-7-3 | 23 PTS | Ball Arena · Denver, CO |
| 21 | Fri Nov 26 | vsSenators | W4-0 | 11-7-3 | 25 PTS | Honda Center · Anaheim, CA |
| 22 | Sun Nov 28 | vsMaple Leafs | L1-5 | 11-8-3 | 25 PTS | Honda Center · Anaheim, CA |
| 23 | Tue Nov 30 | atKings | W5-4 (SO) | 12-8-3 | 27 PTS | Crypto.com Arena · Los Angeles, CA |
| 24 | Wed Dec 1 | vsKnights | W6-5 | 13-8-3 | 29 PTS | Honda Center · Anaheim, CA |
| 25 | Fri Dec 3 | vsFlames | L3-4 (SO) | 13-8-4 | 30 PTS | Honda Center · Anaheim, CA |
| 26 | Mon Dec 6 | atCapitals | L3-4 (SO) | 13-8-5 | 31 PTS | Capital One Arena · Washington, D.C. |
| 27 | Tue Dec 7 | atSabres | W2-0 | 14-8-5 | 33 PTS | KeyBank Center · Buffalo, NY |
| 28 | Thu Dec 9 | atJackets | W2-1 (SO) | 15-8-5 | 35 PTS | Nationwide Arena · Columbus, OH |
| 29 | Sat Dec 11 | atPenguins | L0-1 | 15-9-5 | 35 PTS | PPG Paints Arena · Pittsburgh, PA |
| 30 | Sun Dec 12 | atBlues | W3-2 (OT) | 16-9-5 | 37 PTS | Enterprise Center · St. Louis, MO |
| 31 | Wed Dec 15 | vsKraken | W4-1 | 17-9-5 | 39 PTS | Honda Center · Anaheim, CA |
| 32 | Fri Dec 17 | vsCoyotes | L5-6 (OT) | 17-9-6 | 40 PTS | Honda Center · Anaheim, CA |
| 33 | Wed Dec 29 | vsCanucks | L1-2 (OT) | 17-9-7 | 41 PTS | Honda Center · Anaheim, CA |
| 34 | Fri Dec 31 | atKnights | L1-3 | 17-10-7 | 41 PTS | T-Mobile Arena · Las Vegas, NV |
| 35 | Sun Jan 2 | atAvalanche | L2-4 | 17-11-7 | 41 PTS | Ball Arena · Denver, CO |
| 36 | Tue Jan 4 | vsFlyers | W4-1 | 18-11-7 | 43 PTS | Honda Center · Anaheim, CA |
| 37 | Sat Jan 8 | vsRangers | L1-4 | 18-12-7 | 43 PTS | Honda Center · Anaheim, CA |
| 38 | Sun Jan 9 | vsRed Wings | W4-3 (SO) | 19-12-7 | 45 PTS | Honda Center · Anaheim, CA |
| 39 | Tue Jan 11 | vsPenguins | L1-4 | 19-13-7 | 45 PTS | Honda Center · Anaheim, CA |
| 40 | Fri Jan 14 | atWild | L3-7 | 19-14-7 | 45 PTS | Xcel Energy Center · St. Paul, MN |
| 41 | Sat Jan 15 | atBlackhawks | L0-3 | 19-15-7 | 45 PTS | United Center · Chicago, IL |
| 42 | Wed Jan 19 | vsAvalanche | L0-2 | 19-16-7 | 45 PTS | Honda Center · Anaheim, CA |
| 43 | Fri Jan 21 | vsLightning | W5-1 | 20-16-7 | 47 PTS | Honda Center · Anaheim, CA |
| 44 | Mon Jan 24 | atBruins | W5-3 | 21-16-7 | 49 PTS | TD Garden · Boston, MA |
| 45 | Wed Jan 26 | atMaple Leafs | L3-4 (SO) | 21-16-8 | 50 PTS | Scotiabank Arena · Toronto, ON |
| 46 | Thu Jan 27 | atCanadiens | W5-4 | 22-16-8 | 52 PTS | Bell Centre · Montreal, QC |
| 47 | Sat Jan 29 | atSenators | W2-1 | 23-16-8 | 54 PTS | Canadian Tire Centre · Ottawa, ON |
| 48 | Mon Jan 31 | atRed Wings | L1-2 (OT) | 23-16-9 | 55 PTS | Little Caesars Arena · Detroit, MI |
| 49 | Fri Feb 11 | vsKraken | L3-4 | 23-17-9 | 55 PTS | Honda Center · Anaheim, CA |
| 50 | Wed Feb 16 | atFlames | L2-6 | 23-18-9 | 55 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 51 | Thu Feb 17 | atOilers | L3-7 | 23-19-9 | 55 PTS | Rogers Place · Edmonton, AB |
| 52 | Sat Feb 19 | atCanucks | W7-4 | 24-19-9 | 57 PTS | Rogers Arena · Vancouver, British Columbia |
| 53 | Tue Feb 22 | vsSharks | W4-3 (SO) | 25-19-9 | 59 PTS | Honda Center · Anaheim, CA |
| 54 | Fri Feb 25 | vsKings | L1-4 | 25-20-9 | 59 PTS | Honda Center · Anaheim, CA |
| 55 | Sun Feb 27 | vsIslanders | L0-4 | 25-21-9 | 59 PTS | Honda Center · Anaheim, CA |
| 56 | Tue Mar 1 | vsBruins | W4-3 | 26-21-9 | 61 PTS | Honda Center · Anaheim, CA |
| 57 | Fri Mar 4 | vsKnights | L4-5 | 26-22-9 | 61 PTS | Honda Center · Anaheim, CA |
| 58 | Sun Mar 6 | vsSharks | W3-2 (OT) | 27-22-9 | 63 PTS | Honda Center · Anaheim, CA |
| 59 | Tue Mar 8 | atBlackhawks | L3-8 | 27-23-9 | 63 PTS | United Center · Chicago, IL |
| 60 | Thu Mar 10 | atPredators | L1-4 | 27-24-9 | 63 PTS | Bridgestone Arena · Nashville, TN |
| 61 | Sat Mar 12 | atDevils | L1-2 (SO) | 27-24-10 | 64 PTS | Prudential Center · Newark, NJ |
| 62 | Sun Mar 13 | atIslanders | L3-4 | 27-25-10 | 64 PTS | UBS Arena · Elmont, NY |
| 63 | Tue Mar 15 | atRangers | L3-4 (OT) | 27-25-11 | 65 PTS | Madison Square Garden · Manhattan, NY |
| 64 | Fri Mar 18 | vsPanthers | L0-3 | 27-26-11 | 65 PTS | Honda Center · Anaheim, CA |
| 65 | Mon Mar 21 | vsPredators | L3-6 | 27-27-11 | 65 PTS | Honda Center · Anaheim, CA |
| 66 | Wed Mar 23 | vsBlackhawks | L2-4 | 27-28-11 | 65 PTS | Honda Center · Anaheim, CA |
| 67 | Sat Mar 26 | atSharks | L1-4 | 27-29-11 | 65 PTS | SAP Center · San Jose, CA |
| 68 | Tue Mar 29 | vsStars | L2-3 | 27-30-11 | 65 PTS | Honda Center · Anaheim, CA |
| 69 | Thu Mar 31 | vsStars | L2-3 (OT) | 27-30-12 | 66 PTS | Honda Center · Anaheim, CA |
| 70 | Fri Apr 1 | atCoyotes | W5-0 | 28-30-12 | 68 PTS | Mullett Arena · Tempe, AZ |
| 71 | Sun Apr 3 | vsOilers | L1-6 | 28-31-12 | 68 PTS | Honda Center · Anaheim, CA |
| 72 | Wed Apr 6 | vsFlames | L2-4 | 28-32-12 | 68 PTS | Honda Center · Anaheim, CA |
| 73 | Sat Apr 9 | atFlyers | W5-3 | 29-32-12 | 70 PTS | Wells Fargo Center · Philadelphia, PA |
| 74 | Sun Apr 10 | atHurricanes | L2-5 | 29-33-12 | 70 PTS | PNC Arena · Raleigh, NC |
| 75 | Tue Apr 12 | atPanthers | L2-3 (OT) | 29-33-13 | 71 PTS | Amerant Bank Arena · Sunrise, FL |
| 76 | Thu Apr 14 | atLightning | L3-4 (OT) | 29-33-14 | 72 PTS | AMALIE Arena · Tampa, FL |
| 77 | Sun Apr 17 | vsJackets | W6-4 | 30-33-14 | 74 PTS | Honda Center · Anaheim, CA |
| 78 | Tue Apr 19 | vsKings | L1-2 | 30-34-14 | 74 PTS | Honda Center · Anaheim, CA |
| 79 | Sat Apr 23 | atKings | L2-4 | 30-35-14 | 74 PTS | Crypto.com Arena · Los Angeles, CA |
| 80 | Sun Apr 24 | vsBlues | L3-6 | 30-36-14 | 74 PTS | Honda Center · Anaheim, CA |
| 81 | Tue Apr 26 | atSharks | W5-2 | 31-36-14 | 76 PTS | SAP Center · San Jose, CA |
| 82 | Fri Apr 29 | atStars | L2-4 | 31-37-14 | 76 PTS | American Airlines Center · Dallas, TX |
