| 1 | Sat Oct 14 | at Knights | L1-4 | 0-1-0 | 0 PTS | T-Mobile Arena · Las Vegas, NV |
| 2 | Sun Oct 15 | vsHurricanes | W6-3 | 1-1-0 | 2 PTS | Honda Center · Anaheim, CA |
| 3 | Thu Oct 19 | vsStars | L2-3 | 1-2-0 | 2 PTS | Honda Center · Anaheim, CA |
| 4 | Sat Oct 21 | atCoyotes | L1-2 | 1-3-0 | 2 PTS | Mullett Arena · Tempe, AZ |
| 5 | Sun Oct 22 | vsBruins | L1-3 | 1-4-0 | 2 PTS | Honda Center · Anaheim, CA |
| 6 | Tue Oct 24 | atJackets | W3-2 (OT) | 2-4-0 | 4 PTS | Nationwide Arena · Columbus, OH |
| 7 | Thu Oct 26 | atBruins | W4-3 (OT) | 3-4-0 | 6 PTS | TD Garden · Boston, MA |
| 8 | Sat Oct 28 | atFlyers | W7-4 | 4-4-0 | 8 PTS | Wells Fargo Center · Philadelphia, PA |
| 9 | Mon Oct 30 | atPenguins | W4-3 | 5-4-0 | 10 PTS | PPG Paints Arena · Pittsburgh, PA |
| 10 | Wed Nov 1 | vsCoyotes | W4-3 (OT) | 6-4-0 | 12 PTS | Honda Center · Anaheim, CA |
| 11 | Sun Nov 5 | vsKnights | W4-2 | 7-4-0 | 14 PTS | Honda Center · Anaheim, CA |
| 12 | Tue Nov 7 | vsPenguins | L0-2 | 7-5-0 | 14 PTS | Honda Center · Anaheim, CA |
| 13 | Fri Nov 10 | vsFlyers | L3-6 | 7-6-0 | 14 PTS | Honda Center · Anaheim, CA |
| 14 | Sun Nov 12 | vsSharks | W4-1 | 8-6-0 | 16 PTS | Honda Center · Anaheim, CA |
| 15 | Tue Nov 14 | atPredators | W3-2 | 9-6-0 | 18 PTS | Bridgestone Arena · Nashville, TN |
| 16 | Wed Nov 15 | atAvalanche | L2-8 | 9-7-0 | 18 PTS | Ball Arena · Denver, CO |
| 17 | Fri Nov 17 | vsPanthers | L1-2 | 9-8-0 | 18 PTS | Honda Center · Anaheim, CA |
| 18 | Sun Nov 19 | vsBlues | L1-3 | 9-9-0 | 18 PTS | Honda Center · Anaheim, CA |
| 19 | Wed Nov 22 | vsCanadiens | L3-4 | 9-10-0 | 18 PTS | Honda Center · Anaheim, CA |
| 20 | Fri Nov 24 | vsKings | L2-5 | 9-11-0 | 18 PTS | Honda Center · Anaheim, CA |
| 21 | Sun Nov 26 | atOilers | L2-8 | 9-12-0 | 18 PTS | Rogers Place · Edmonton, AB |
| 22 | Tue Nov 28 | atCanucks | L1-3 | 9-13-0 | 18 PTS | Rogers Arena · Vancouver, British Columbia |
| 23 | Thu Nov 30 | vsCapitals | L4-5 | 9-14-0 | 18 PTS | Honda Center · Anaheim, CA |
| 24 | Sat Dec 2 | vsAvalanche | W4-3 (SO) | 10-14-0 | 20 PTS | Honda Center · Anaheim, CA |
| 25 | Tue Dec 5 | atAvalanche | L2-3 | 10-15-0 | 20 PTS | Ball Arena · Denver, CO |
| 26 | Thu Dec 7 | atBlackhawks | L0-1 | 10-16-0 | 20 PTS | United Center · Chicago, IL |
| 27 | Sun Dec 10 | vsJets | L2-4 | 10-17-0 | 20 PTS | Honda Center · Anaheim, CA |
| 28 | Wed Dec 13 | atIslanders | L3-4 | 10-18-0 | 20 PTS | UBS Arena · Elmont, NY |
| 29 | Fri Dec 15 | atRangers | L1-5 | 10-19-0 | 20 PTS | Madison Square Garden · Manhattan, NY |
| 30 | Sun Dec 17 | atDevils | W5-1 | 11-19-0 | 22 PTS | Prudential Center · Newark, NJ |
| 31 | Mon Dec 18 | atRed Wings | W4-3 | 12-19-0 | 24 PTS | Little Caesars Arena · Detroit, MI |
| 32 | Thu Dec 21 | vsFlames | L0-3 | 12-20-0 | 24 PTS | Honda Center · Anaheim, CA |
| 33 | Sat Dec 23 | vsKraken | L2-3 | 12-21-0 | 24 PTS | Honda Center · Anaheim, CA |
| 34 | Wed Dec 27 | vsKnights | W5-2 | 13-21-0 | 26 PTS | Honda Center · Anaheim, CA |
| 35 | Fri Dec 29 | vsCoyotes | L0-2 | 13-22-0 | 26 PTS | Honda Center · Anaheim, CA |
| 36 | Sun Dec 31 | vsOilers | L2-7 | 13-23-0 | 26 PTS | Honda Center · Anaheim, CA |
| 37 | Wed Jan 3 | vsMaple Leafs | L1-2 (OT) | 13-23-1 | 27 PTS | Honda Center · Anaheim, CA |
| 38 | Fri Jan 5 | vsJets | L1-3 | 13-24-1 | 27 PTS | Honda Center · Anaheim, CA |
| 39 | Sun Jan 7 | vsRed Wings | L2-3 | 13-25-1 | 27 PTS | Honda Center · Anaheim, CA |
| 40 | Tue Jan 9 | atPredators | W5-3 | 14-25-1 | 29 PTS | Bridgestone Arena · Nashville, TN |
| 41 | Thu Jan 11 | atHurricanes | L3-6 | 14-26-1 | 29 PTS | PNC Arena · Raleigh, NC |
| 42 | Sat Jan 13 | atLightning | L1-5 | 14-27-1 | 29 PTS | AMALIE Arena · Tampa, FL |
| 43 | Mon Jan 15 | atPanthers | W5-4 (OT) | 15-27-1 | 31 PTS | Amerant Bank Arena · Sunrise, FL |
| 44 | Tue Jan 16 | atCapitals | L0-2 | 15-28-1 | 31 PTS | Capital One Arena · Washington, D.C. |
| 45 | Sat Jan 20 | atSharks | L3-5 | 15-29-1 | 31 PTS | SAP Center · San Jose, CA |
| 46 | Sun Jan 21 | vsRangers | L2-5 | 15-30-1 | 31 PTS | Honda Center · Anaheim, CA |
| 47 | Tue Jan 23 | vsSabres | W4-2 | 16-30-1 | 33 PTS | Honda Center · Anaheim, CA |
| 48 | Thu Jan 25 | atStars | L3-4 (OT) | 16-30-2 | 34 PTS | American Airlines Center · Dallas, TX |
| 49 | Sat Jan 27 | atWild | W3-2 | 17-30-2 | 36 PTS | Xcel Energy Center · St. Paul, MN |
| 50 | Wed Jan 31 | vsSharks | W3-2 (OT) | 18-30-2 | 38 PTS | Honda Center · Anaheim, CA |
| 51 | Fri Feb 9 | vsOilers | L3-5 | 18-31-2 | 38 PTS | Honda Center · Anaheim, CA |
| 52 | Tue Feb 13 | atCanadiens | L0-5 | 18-32-2 | 38 PTS | Bell Centre · Montreal, QC |
| 53 | Thu Feb 15 | atSenators | W5-1 | 19-32-2 | 40 PTS | Canadian Tire Centre · Ottawa, ON |
| 54 | Sat Feb 17 | atMaple Leafs | L2-9 | 19-33-2 | 40 PTS | Scotiabank Arena · Toronto, ON |
| 55 | Mon Feb 19 | atSabres | W4-3 | 20-33-2 | 42 PTS | KeyBank Center · Buffalo, NY |
| 56 | Wed Feb 21 | vsJackets | L4-7 | 20-34-2 | 42 PTS | Honda Center · Anaheim, CA |
| 57 | Sat Feb 24 | atKings | L2-3 (SO) | 20-34-3 | 43 PTS | Crypto.com Arena · Los Angeles, CA |
| 58 | Sun Feb 25 | vsPredators | L2-4 | 20-35-3 | 43 PTS | Honda Center · Anaheim, CA |
| 59 | Thu Feb 29 | atSharks | W6-4 | 21-35-3 | 45 PTS | SAP Center · San Jose, CA |
| 60 | Fri Mar 1 | vsDevils | W4-3 | 22-35-3 | 47 PTS | Honda Center · Anaheim, CA |
| 61 | Sun Mar 3 | vsCanucks | L1-2 | 22-36-3 | 47 PTS | Honda Center · Anaheim, CA |
| 62 | Wed Mar 6 | vsSenators | W2-1 | 23-36-3 | 49 PTS | Honda Center · Anaheim, CA |
| 63 | Fri Mar 8 | vsStars | L2-6 | 23-37-3 | 49 PTS | Honda Center · Anaheim, CA |
| 64 | Sun Mar 10 | vsIslanders | L1-6 | 23-38-3 | 49 PTS | Honda Center · Anaheim, CA |
| 65 | Tue Mar 12 | atBlackhawks | L2-7 | 23-39-3 | 49 PTS | United Center · Chicago, IL |
| 66 | Thu Mar 14 | atWild | L0-2 | 23-40-3 | 49 PTS | Xcel Energy Center · St. Paul, MN |
| 67 | Fri Mar 15 | atJets | L0-6 | 23-41-3 | 49 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 68 | Sun Mar 17 | atBlues | L2-4 | 23-42-3 | 49 PTS | Enterprise Center · St. Louis, MO |
| 69 | Tue Mar 19 | vsWild | L0-4 | 23-43-3 | 49 PTS | Honda Center · Anaheim, CA |
| 70 | Thu Mar 21 | vsBlackhawks | W4-0 | 24-43-3 | 51 PTS | Honda Center · Anaheim, CA |
| 71 | Sun Mar 24 | vsLightning | L2-3 (OT) | 24-43-4 | 52 PTS | Honda Center · Anaheim, CA |
| 72 | Tue Mar 26 | atKraken | L0-4 | 24-44-4 | 52 PTS | Climate Pledge Arena · Seattle, WA |
| 73 | Thu Mar 28 | atKraken | L2-4 | 24-45-4 | 52 PTS | Climate Pledge Arena · Seattle, WA |
| 74 | Sat Mar 30 | atOilers | L1-6 | 24-46-4 | 52 PTS | Rogers Place · Edmonton, AB |
| 75 | Sun Mar 31 | atCanucks | L2-3 | 24-47-4 | 52 PTS | Rogers Arena · Vancouver, British Columbia |
| 76 | Tue Apr 2 | atFlames | W5-3 | 25-47-4 | 54 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 77 | Fri Apr 5 | vsKraken | L1-3 | 25-48-4 | 54 PTS | Honda Center · Anaheim, CA |
| 78 | Sun Apr 7 | vsBlues | L5-6 (SO) | 25-48-5 | 55 PTS | Honda Center · Anaheim, CA |
| 79 | Tue Apr 9 | vsKings | W3-1 | 26-48-5 | 57 PTS | Honda Center · Anaheim, CA |
| 80 | Fri Apr 12 | vsFlames | L3-6 | 26-49-5 | 57 PTS | Honda Center · Anaheim, CA |
| 81 | Sat Apr 13 | atKings | L1-3 | 26-50-5 | 57 PTS | Crypto.com Arena · Los Angeles, CA |
| 82 | Thu Apr 18 | atKnights | W4-1 | 27-50-5 | 59 PTS | T-Mobile Arena · Las Vegas, NV |
