| 1 | Wed Oct 13 | vs Blackhawks | W4-2 | 1-0-0 | 2 PTS | Ball Arena · Denver, CO |
| 2 | Sat Oct 16 | vsBlues | L3-5 | 1-1-0 | 2 PTS | Ball Arena · Denver, CO |
| 3 | Tue Oct 19 | atCapitals | L3-6 | 1-2-0 | 2 PTS | Capital One Arena · Washington, D.C. |
| 4 | Thu Oct 21 | atPanthers | L1-4 | 1-3-0 | 2 PTS | Amerant Bank Arena · Sunrise, FL |
| 5 | Sat Oct 23 | atLightning | W4-3 (SO) | 2-3-0 | 4 PTS | AMALIE Arena · Tampa, FL |
| 6 | Tue Oct 26 | vsKnights | L1-3 | 2-4-0 | 4 PTS | Ball Arena · Denver, CO |
| 7 | Thu Oct 28 | atBlues | W4-3 | 3-4-0 | 6 PTS | Enterprise Center · St. Louis, MO |
| 8 | Sat Oct 30 | vsWild | W4-1 | 4-4-0 | 8 PTS | Ball Arena · Denver, CO |
| 9 | Wed Nov 3 | vsJackets | L4-5 (OT) | 4-4-1 | 9 PTS | Ball Arena · Denver, CO |
| 10 | Sat Nov 6 | atJackets | L2-4 | 4-5-1 | 9 PTS | Nationwide Arena · Columbus, OH |
| 11 | Thu Nov 11 | vsCanucks | W7-1 | 5-5-1 | 11 PTS | Ball Arena · Denver, CO |
| 12 | Sat Nov 13 | vsSharks | W6-2 | 6-5-1 | 13 PTS | Ball Arena · Denver, CO |
| 13 | Wed Nov 17 | atCanucks | W4-2 | 7-5-1 | 15 PTS | Rogers Arena · Vancouver, British Columbia |
| 14 | Fri Nov 19 | atKraken | W7-3 | 8-5-1 | 17 PTS | Climate Pledge Arena · Seattle, WA |
| 15 | Mon Nov 22 | vsSenators | W7-5 | 9-5-1 | 19 PTS | Ball Arena · Denver, CO |
| 16 | Wed Nov 24 | vsDucks | W5-2 | 10-5-1 | 21 PTS | Ball Arena · Denver, CO |
| 17 | Fri Nov 26 | atStars | L1-3 | 10-6-1 | 21 PTS | American Airlines Center · Dallas, TX |
| 18 | Sat Nov 27 | vsPredators | W6-2 | 11-6-1 | 23 PTS | Ball Arena · Denver, CO |
| 19 | Wed Dec 1 | atMaple Leafs | L3-8 | 11-7-1 | 23 PTS | Scotiabank Arena · Toronto, ON |
| 20 | Thu Dec 2 | atCanadiens | W4-1 | 12-7-1 | 25 PTS | Bell Centre · Montreal, QC |
| 21 | Sat Dec 4 | atSenators | L5-6 (OT) | 12-7-2 | 26 PTS | Canadian Tire Centre · Ottawa, ON |
| 22 | Mon Dec 6 | atFlyers | W7-5 | 13-7-2 | 28 PTS | Wells Fargo Center · Philadelphia, PA |
| 23 | Wed Dec 8 | atRangers | W7-3 | 14-7-2 | 30 PTS | Madison Square Garden · Manhattan, NY |
| 24 | Fri Dec 10 | vsRed Wings | W7-3 | 15-7-2 | 32 PTS | Ball Arena · Denver, CO |
| 25 | Sun Dec 12 | vsPanthers | W3-2 | 16-7-2 | 34 PTS | Ball Arena · Denver, CO |
| 26 | Tue Dec 14 | vsRangers | W4-2 | 17-7-2 | 36 PTS | Ball Arena · Denver, CO |
| 27 | Thu Dec 16 | atPredators | L2-5 | 17-8-2 | 36 PTS | Bridgestone Arena · Nashville, TN |
| 28 | Sun Jan 2 | vsDucks | W4-2 | 18-8-2 | 38 PTS | Ball Arena · Denver, CO |
| 29 | Tue Jan 4 | atBlackhawks | W4-3 (OT) | 19-8-2 | 40 PTS | United Center · Chicago, IL |
| 30 | Thu Jan 6 | vsJets | W7-1 | 20-8-2 | 42 PTS | Ball Arena · Denver, CO |
| 31 | Sat Jan 8 | vsMaple Leafs | W5-4 (OT) | 21-8-2 | 44 PTS | Ball Arena · Denver, CO |
| 32 | Mon Jan 10 | vsKraken | W4-3 | 22-8-2 | 46 PTS | Ball Arena · Denver, CO |
| 33 | Tue Jan 11 | atPredators | L4-5 (OT) | 22-8-3 | 47 PTS | Bridgestone Arena · Nashville, TN |
| 34 | Fri Jan 14 | vsCoyotes | W4-3 (SO) | 23-8-3 | 49 PTS | Ball Arena · Denver, CO |
| 35 | Sat Jan 15 | atCoyotes | W5-0 | 24-8-3 | 51 PTS | Mullett Arena · Tempe, AZ |
| 36 | Mon Jan 17 | vsWild | W4-3 (SO) | 25-8-3 | 53 PTS | Ball Arena · Denver, CO |
| 37 | Wed Jan 19 | atDucks | W2-0 | 26-8-3 | 55 PTS | Honda Center · Anaheim, CA |
| 38 | Thu Jan 20 | atKings | W4-1 | 27-8-3 | 57 PTS | Crypto.com Arena · Los Angeles, CA |
| 39 | Sat Jan 22 | vsCanadiens | W3-2 (OT) | 28-8-3 | 59 PTS | Ball Arena · Denver, CO |
| 40 | Mon Jan 24 | vsBlackhawks | W2-0 | 29-8-3 | 61 PTS | Ball Arena · Denver, CO |
| 41 | Wed Jan 26 | vsBruins | W4-3 (OT) | 30-8-3 | 63 PTS | Ball Arena · Denver, CO |
| 42 | Fri Jan 28 | atBlackhawks | W6-4 | 31-8-3 | 65 PTS | United Center · Chicago, IL |
| 43 | Sun Jan 30 | vsSabres | W4-1 | 32-8-3 | 67 PTS | Ball Arena · Denver, CO |
| 44 | Tue Feb 1 | vsCoyotes | L2-3 (SO) | 32-8-4 | 68 PTS | Ball Arena · Denver, CO |
| 45 | Thu Feb 10 | vsLightning | W3-2 | 33-8-4 | 70 PTS | Ball Arena · Denver, CO |
| 46 | Sun Feb 13 | atStars | W4-0 | 34-8-4 | 72 PTS | American Airlines Center · Dallas, TX |
| 47 | Tue Feb 15 | vsStars | L1-4 | 34-9-4 | 72 PTS | Ball Arena · Denver, CO |
| 48 | Wed Feb 16 | atKnights | W2-0 | 35-9-4 | 74 PTS | T-Mobile Arena · Las Vegas, NV |
| 49 | Sat Feb 19 | atSabres | W5-3 | 36-9-4 | 76 PTS | KeyBank Center · Buffalo, NY |
| 50 | Mon Feb 21 | atBruins | L1-5 | 36-10-4 | 76 PTS | TD Garden · Boston, MA |
| 51 | Wed Feb 23 | atRed Wings | W5-2 | 37-10-4 | 78 PTS | Little Caesars Arena · Detroit, MI |
| 52 | Fri Feb 25 | vsJets | W6-3 | 38-10-4 | 80 PTS | Ball Arena · Denver, CO |
| 53 | Sat Feb 26 | atKnights | W3-2 | 39-10-4 | 82 PTS | T-Mobile Arena · Las Vegas, NV |
| 54 | Tue Mar 1 | vsIslanders | W5-3 | 40-10-4 | 84 PTS | Ball Arena · Denver, CO |
| 55 | Thu Mar 3 | atCoyotes | L1-2 | 40-11-4 | 84 PTS | Mullett Arena · Tempe, AZ |
| 56 | Sat Mar 5 | vsFlames | L3-4 (OT) | 40-11-5 | 85 PTS | Ball Arena · Denver, CO |
| 57 | Mon Mar 7 | atIslanders | W5-4 | 41-11-5 | 87 PTS | UBS Arena · Elmont, NY |
| 58 | Tue Mar 8 | atDevils | L3-5 | 41-12-5 | 87 PTS | Prudential Center · Newark, NJ |
| 59 | Thu Mar 10 | atHurricanes | L0-2 | 41-13-5 | 87 PTS | PNC Arena · Raleigh, NC |
| 60 | Sun Mar 13 | vsFlames | W3-0 | 42-13-5 | 89 PTS | Ball Arena · Denver, CO |
| 61 | Tue Mar 15 | atKings | W3-0 | 43-13-5 | 91 PTS | Crypto.com Arena · Los Angeles, CA |
| 62 | Fri Mar 18 | atSharks | W5-3 | 44-13-5 | 93 PTS | SAP Center · San Jose, CA |
| 63 | Mon Mar 21 | vsOilers | W3-2 (OT) | 45-13-5 | 95 PTS | Ball Arena · Denver, CO |
| 64 | Wed Mar 23 | vsCanucks | L1-3 | 45-14-5 | 95 PTS | Ball Arena · Denver, CO |
| 65 | Fri Mar 25 | vsFlyers | W6-3 | 46-14-5 | 97 PTS | Ball Arena · Denver, CO |
| 66 | Sun Mar 27 | atWild | L2-3 (OT) | 46-14-6 | 98 PTS | Xcel Energy Center · St. Paul, MN |
| 67 | Tue Mar 29 | atFlames | W2-1 | 47-14-6 | 100 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 68 | Thu Mar 31 | vsSharks | W4-2 | 48-14-6 | 102 PTS | Ball Arena · Denver, CO |
| 69 | Sat Apr 2 | vsPenguins | W3-2 | 49-14-6 | 104 PTS | Ball Arena · Denver, CO |
| 70 | Tue Apr 5 | atPenguins | W6-4 | 50-14-6 | 106 PTS | PPG Paints Arena · Pittsburgh, PA |
| 71 | Fri Apr 8 | atJets | W5-4 (OT) | 51-14-6 | 108 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 72 | Sat Apr 9 | atOilers | W2-1 (SO) | 52-14-6 | 110 PTS | Rogers Place · Edmonton, AB |
| 73 | Wed Apr 13 | vsKings | W9-3 | 53-14-6 | 112 PTS | Ball Arena · Denver, CO |
| 74 | Thu Apr 14 | vsDevils | W3-1 | 54-14-6 | 114 PTS | Ball Arena · Denver, CO |
| 75 | Sat Apr 16 | vsHurricanes | W7-4 | 55-14-6 | 116 PTS | Ball Arena · Denver, CO |
| 76 | Mon Apr 18 | vsCapitals | L2-3 | 55-15-6 | 116 PTS | Ball Arena · Denver, CO |
| 77 | Wed Apr 20 | atKraken | L2-3 | 55-16-6 | 116 PTS | Climate Pledge Arena · Seattle, WA |
| 78 | Fri Apr 22 | atOilers | L3-6 | 55-17-6 | 116 PTS | Rogers Place · Edmonton, AB |
| 79 | Sun Apr 24 | atJets | L1-4 | 55-18-6 | 116 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 80 | Tue Apr 26 | vsBlues | W5-3 | 56-18-6 | 118 PTS | Ball Arena · Denver, CO |
| 81 | Thu Apr 28 | vsPredators | L4-5 (SO) | 56-18-7 | 119 PTS | Ball Arena · Denver, CO |
| 82 | Fri Apr 29 | atWild | L1-4 | 56-19-7 | 119 PTS | Xcel Energy Center · St. Paul, MN |
| 1 | Tue May 3 | vsPredators | W7-2 | 1-0 | 1.000 | Ball Arena · Denver, CO |
| 2 | Thu May 5 | vsPredators | W2-1 (OT) | 2-0 | 1.000 | Ball Arena · Denver, CO |
| 3 | Sat May 7 | atPredators | W7-3 | 3-0 | 1.000 | Bridgestone Arena · Nashville, TN |
| 4 | Mon May 9 | atPredators | W5-3 | 4-0 | 1.000 | Bridgestone Arena · Nashville, TN |
| 1 | Tue May 17 | vsBlues | W3-2 (OT) | 1-0 | 1.000 | Ball Arena · Denver, CO |
| 2 | Thu May 19 | vsBlues | L1-4 | 1-1 | .500 | Ball Arena · Denver, CO |
| 3 | Sat May 21 | atBlues | W5-2 | 2-1 | .667 | Enterprise Center · St. Louis, MO |
| 4 | Mon May 23 | atBlues | W6-3 | 3-1 | .750 | Enterprise Center · St. Louis, MO |
| 5 | Wed May 25 | vsBlues | L4-5 (OT) | 3-2 | .600 | Ball Arena · Denver, CO |
| 6 | Fri May 27 | atBlues | W3-2 | 4-2 | .667 | Enterprise Center · St. Louis, MO |
| 1 | Tue May 31 | vsOilers | W8-6 | 1-0 | 1.000 | Ball Arena · Denver, CO |
| 2 | Thu Jun 2 | vsOilers | W4-0 | 2-0 | 1.000 | Ball Arena · Denver, CO |
| 3 | Sat Jun 4 | atOilers | W4-2 | 3-0 | 1.000 | Rogers Place · Edmonton, AB |
| 4 | Mon Jun 6 | atOilers | W6-5 (OT) | 4-0 | 1.000 | Rogers Place · Edmonton, AB |
| 1 | Wed Jun 15 | vsLightning | W4-3 (OT) | 1-0 | 1.000 | Ball Arena · Denver, CO |
| 2 | Sat Jun 18 | vsLightning | W7-0 | 2-0 | 1.000 | Ball Arena · Denver, CO |
| 3 | Mon Jun 20 | atLightning | L2-6 | 2-1 | .667 | AMALIE Arena · Tampa, FL |
| 4 | Wed Jun 22 | atLightning | W3-2 (OT) | 3-1 | .750 | AMALIE Arena · Tampa, FL |
| 5 | Fri Jun 24 | vsLightning | L2-3 | 3-2 | .600 | Ball Arena · Denver, CO |
| 6 | Sun Jun 26 | atLightning | W2-1 | 4-2 | .667 | AMALIE Arena · Tampa, FL |
