| 1 | Wed Oct 11 | at Kings | W5-2 | 1-0-0 | 2 PTS | Crypto.com Arena · Los Angeles, CA |
| 2 | Sat Oct 14 | atSharks | W2-1 (SO) | 2-0-0 | 4 PTS | SAP Center · San Jose, CA |
| 3 | Tue Oct 17 | atKraken | W4-1 | 3-0-0 | 6 PTS | Climate Pledge Arena · Seattle, WA |
| 4 | Thu Oct 19 | vsBlackhawks | W4-0 | 4-0-0 | 8 PTS | Ball Arena · Denver, CO |
| 5 | Sat Oct 21 | vsHurricanes | W6-4 | 5-0-0 | 10 PTS | Ball Arena · Denver, CO |
| 6 | Tue Oct 24 | atIslanders | W7-4 | 6-0-0 | 12 PTS | UBS Arena · Elmont, NY |
| 7 | Thu Oct 26 | atPenguins | L0-4 | 6-1-0 | 12 PTS | PPG Paints Arena · Pittsburgh, PA |
| 8 | Sun Oct 29 | atSabres | L0-4 | 6-2-0 | 12 PTS | KeyBank Center · Buffalo, NY |
| 9 | Wed Nov 1 | vsBlues | W4-1 | 7-2-0 | 14 PTS | Ball Arena · Denver, CO |
| 10 | Sat Nov 4 | atKnights | L0-7 | 7-3-0 | 14 PTS | T-Mobile Arena · Las Vegas, NV |
| 11 | Tue Nov 7 | vsDevils | W6-3 | 8-3-0 | 16 PTS | Ball Arena · Denver, CO |
| 12 | Thu Nov 9 | vsKraken | L3-4 | 8-4-0 | 16 PTS | Ball Arena · Denver, CO |
| 13 | Sat Nov 11 | vsBlues | L2-8 | 8-5-0 | 16 PTS | Ball Arena · Denver, CO |
| 14 | Mon Nov 13 | atKraken | W5-1 | 9-5-0 | 18 PTS | Climate Pledge Arena · Seattle, WA |
| 15 | Wed Nov 15 | vsDucks | W8-2 | 10-5-0 | 20 PTS | Ball Arena · Denver, CO |
| 16 | Sat Nov 18 | atStars | W6-3 | 11-5-0 | 22 PTS | American Airlines Center · Dallas, TX |
| 17 | Mon Nov 20 | atPredators | L3-4 | 11-6-0 | 22 PTS | Bridgestone Arena · Nashville, TN |
| 18 | Wed Nov 22 | vsCanucks | W5-2 | 12-6-0 | 24 PTS | Ball Arena · Denver, CO |
| 19 | Fri Nov 24 | atWild | W3-2 | 13-6-0 | 26 PTS | Xcel Energy Center · St. Paul, MN |
| 20 | Sat Nov 25 | vsFlames | W3-1 | 14-6-0 | 28 PTS | Ball Arena · Denver, CO |
| 21 | Mon Nov 27 | vsLightning | W4-1 | 15-6-0 | 30 PTS | Ball Arena · Denver, CO |
| 22 | Thu Nov 30 | atCoyotes | L3-4 (OT) | 15-6-1 | 31 PTS | Mullett Arena · Tempe, AZ |
| 23 | Sat Dec 2 | atDucks | L3-4 (SO) | 15-6-2 | 32 PTS | Honda Center · Anaheim, CA |
| 24 | Sun Dec 3 | atKings | L1-4 | 15-7-2 | 32 PTS | Crypto.com Arena · Los Angeles, CA |
| 25 | Tue Dec 5 | vsDucks | W3-2 | 16-7-2 | 34 PTS | Ball Arena · Denver, CO |
| 26 | Thu Dec 7 | vsJets | L2-4 | 16-8-2 | 34 PTS | Ball Arena · Denver, CO |
| 27 | Sat Dec 9 | vsFlyers | L2-5 | 16-9-2 | 34 PTS | Ball Arena · Denver, CO |
| 28 | Mon Dec 11 | vsFlames | W6-5 | 17-9-2 | 36 PTS | Ball Arena · Denver, CO |
| 29 | Wed Dec 13 | vsSabres | W5-1 | 18-9-2 | 38 PTS | Ball Arena · Denver, CO |
| 30 | Sat Dec 16 | atJets | L2-6 | 18-10-2 | 38 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 31 | Sun Dec 17 | vsSharks | W6-2 | 19-10-2 | 40 PTS | Ball Arena · Denver, CO |
| 32 | Tue Dec 19 | atBlackhawks | L2-3 | 19-11-2 | 40 PTS | United Center · Chicago, IL |
| 33 | Thu Dec 21 | vsSenators | W6-4 | 20-11-2 | 42 PTS | Ball Arena · Denver, CO |
| 34 | Sat Dec 23 | vsCoyotes | W4-1 | 21-11-2 | 44 PTS | Ball Arena · Denver, CO |
| 35 | Wed Dec 27 | atCoyotes | L4-5 (OT) | 21-11-3 | 45 PTS | Mullett Arena · Tempe, AZ |
| 36 | Fri Dec 29 | atBlues | W2-1 | 22-11-3 | 47 PTS | Enterprise Center · St. Louis, MO |
| 37 | Sun Dec 31 | vsSharks | W3-1 | 23-11-3 | 49 PTS | Ball Arena · Denver, CO |
| 38 | Tue Jan 2 | vsIslanders | W5-4 (OT) | 24-11-3 | 51 PTS | Ball Arena · Denver, CO |
| 39 | Thu Jan 4 | atStars | W5-4 (OT) | 25-11-3 | 53 PTS | American Airlines Center · Dallas, TX |
| 40 | Sat Jan 6 | vsPanthers | L4-8 | 25-12-3 | 53 PTS | Ball Arena · Denver, CO |
| 41 | Mon Jan 8 | vsBruins | W4-3 (SO) | 26-12-3 | 55 PTS | Ball Arena · Denver, CO |
| 42 | Wed Jan 10 | vsKnights | W3-0 | 27-12-3 | 57 PTS | Ball Arena · Denver, CO |
| 43 | Sat Jan 13 | atMaple Leafs | W5-3 | 28-12-3 | 59 PTS | Scotiabank Arena · Toronto, ON |
| 44 | Mon Jan 15 | atCanadiens | L3-4 | 28-13-3 | 59 PTS | Bell Centre · Montreal, QC |
| 45 | Tue Jan 16 | atSenators | W7-4 | 29-13-3 | 61 PTS | Canadian Tire Centre · Ottawa, ON |
| 46 | Thu Jan 18 | atBruins | L2-5 | 29-14-3 | 61 PTS | TD Garden · Boston, MA |
| 47 | Sat Jan 20 | atFlyers | W7-4 | 30-14-3 | 63 PTS | Wells Fargo Center · Philadelphia, PA |
| 48 | Wed Jan 24 | vsCapitals | W6-2 | 31-14-3 | 65 PTS | Ball Arena · Denver, CO |
| 49 | Fri Jan 26 | vsKings | W5-1 | 32-14-3 | 67 PTS | Ball Arena · Denver, CO |
| 50 | Mon Feb 5 | atRangers | L1-2 (OT) | 32-14-4 | 68 PTS | Madison Square Garden · Manhattan, NY |
| 51 | Tue Feb 6 | atDevils | L3-5 | 32-15-4 | 68 PTS | Prudential Center · Newark, NJ |
| 52 | Thu Feb 8 | atHurricanes | L2-5 | 32-16-4 | 68 PTS | PNC Arena · Raleigh, NC |
| 53 | Sat Feb 10 | atPanthers | L0-4 | 32-17-4 | 68 PTS | Amerant Bank Arena · Sunrise, FL |
| 54 | Tue Feb 13 | atCapitals | W6-3 | 33-17-4 | 70 PTS | Capital One Arena · Washington, D.C. |
| 55 | Thu Feb 15 | atLightning | L3-6 | 33-18-4 | 70 PTS | AMALIE Arena · Tampa, FL |
| 56 | Sun Feb 18 | vsCoyotes | W4-3 | 34-18-4 | 72 PTS | Ball Arena · Denver, CO |
| 57 | Tue Feb 20 | vsCanucks | W3-1 | 35-18-4 | 74 PTS | Ball Arena · Denver, CO |
| 58 | Thu Feb 22 | atRed Wings | L1-2 (OT) | 35-18-5 | 75 PTS | Little Caesars Arena · Detroit, MI |
| 59 | Sat Feb 24 | vsMaple Leafs | L3-4 | 35-19-5 | 75 PTS | Ball Arena · Denver, CO |
| 60 | Tue Feb 27 | vsStars | W5-1 | 36-19-5 | 77 PTS | Ball Arena · Denver, CO |
| 61 | Thu Feb 29 | atBlackhawks | W5-0 | 37-19-5 | 79 PTS | United Center · Chicago, IL |
| 62 | Sat Mar 2 | atPredators | L1-5 | 37-20-5 | 79 PTS | Bridgestone Arena · Nashville, TN |
| 63 | Mon Mar 4 | vsBlackhawks | W5-0 | 38-20-5 | 81 PTS | Ball Arena · Denver, CO |
| 64 | Wed Mar 6 | vsRed Wings | W7-2 | 39-20-5 | 83 PTS | Ball Arena · Denver, CO |
| 65 | Fri Mar 8 | vsWild | W2-1 (OT) | 40-20-5 | 85 PTS | Ball Arena · Denver, CO |
| 66 | Tue Mar 12 | atFlames | W6-2 | 41-20-5 | 87 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 67 | Wed Mar 13 | atCanucks | W4-3 (OT) | 42-20-5 | 89 PTS | Rogers Arena · Vancouver, British Columbia |
| 68 | Sat Mar 16 | atOilers | W3-2 (OT) | 43-20-5 | 91 PTS | Rogers Place · Edmonton, AB |
| 69 | Tue Mar 19 | atBlues | W4-3 | 44-20-5 | 93 PTS | Enterprise Center · St. Louis, MO |
| 70 | Fri Mar 22 | vsJackets | W6-1 | 45-20-5 | 95 PTS | Ball Arena · Denver, CO |
| 71 | Sun Mar 24 | vsPenguins | W5-4 (OT) | 46-20-5 | 97 PTS | Ball Arena · Denver, CO |
| 72 | Tue Mar 26 | vsCanadiens | L1-2 | 46-21-5 | 97 PTS | Ball Arena · Denver, CO |
| 73 | Thu Mar 28 | vsRangers | L2-3 (SO) | 46-21-6 | 98 PTS | Ball Arena · Denver, CO |
| 74 | Sat Mar 30 | vsPredators | W7-4 | 47-21-6 | 100 PTS | Ball Arena · Denver, CO |
| 75 | Mon Apr 1 | atJackets | L1-4 | 47-22-6 | 100 PTS | Nationwide Arena · Columbus, OH |
| 76 | Thu Apr 4 | atWild | W5-2 | 48-22-6 | 102 PTS | Xcel Energy Center · St. Paul, MN |
| 77 | Fri Apr 5 | atOilers | L2-6 | 48-23-6 | 102 PTS | Rogers Place · Edmonton, AB |
| 78 | Sun Apr 7 | vsStars | L4-7 | 48-24-6 | 102 PTS | Ball Arena · Denver, CO |
| 79 | Tue Apr 9 | vsWild | W5-2 | 49-24-6 | 104 PTS | Ball Arena · Denver, CO |
| 80 | Sat Apr 13 | vsJets | L0-7 | 49-25-6 | 104 PTS | Ball Arena · Denver, CO |
| 81 | Sun Apr 14 | atKnights | L3-4 (OT) | 49-25-7 | 105 PTS | T-Mobile Arena · Las Vegas, NV |
| 82 | Thu Apr 18 | vsOilers | W5-1 | 50-25-7 | 107 PTS | Ball Arena · Denver, CO |
| 1 | Sun Apr 21 | atJets | L6-7 | 0-1 | .000 | Canada Life Centre · Winnipeg, Manitoba |
| 2 | Tue Apr 23 | atJets | W5-2 | 1-1 | .500 | Canada Life Centre · Winnipeg, Manitoba |
| 3 | Fri Apr 26 | vsJets | W6-2 | 2-1 | .667 | Ball Arena · Denver, CO |
| 4 | Sun Apr 28 | vsJets | W5-1 | 3-1 | .750 | Ball Arena · Denver, CO |
| 5 | Tue Apr 30 | atJets | W6-3 | 4-1 | .800 | Canada Life Centre · Winnipeg, Manitoba |
| 1 | Tue May 7 | atStars | W4-3 (OT) | 1-0 | 1.000 | American Airlines Center · Dallas, TX |
| 2 | Thu May 9 | atStars | L3-5 | 1-1 | .500 | American Airlines Center · Dallas, TX |
| 3 | Sat May 11 | vsStars | L1-4 | 1-2 | .333 | Ball Arena · Denver, CO |
| 4 | Mon May 13 | vsStars | L1-5 | 1-3 | .250 | Ball Arena · Denver, CO |
| 5 | Wed May 15 | atStars | W5-3 | 2-3 | .400 | American Airlines Center · Dallas, TX |
| 6 | Fri May 17 | vsStars | L1-2 (OT) | 2-4 | .333 | Ball Arena · Denver, CO |
