| 1 | Tue Oct 12 | vs Penguins | L2-6 | 0-1-0 | 0 PTS | AMALIE Arena · Tampa, FL |
| 2 | Thu Oct 14 | atRed Wings | W7-6 (OT) | 1-1-0 | 2 PTS | Little Caesars Arena · Detroit, MI |
| 3 | Sat Oct 16 | atCapitals | W2-1 (OT) | 2-1-0 | 4 PTS | Capital One Arena · Washington, D.C. |
| 4 | Tue Oct 19 | vsPanthers | L1-4 | 2-2-0 | 4 PTS | AMALIE Arena · Tampa, FL |
| 5 | Sat Oct 23 | vsAvalanche | L3-4 (SO) | 2-2-1 | 5 PTS | AMALIE Arena · Tampa, FL |
| 6 | Mon Oct 25 | atSabres | L1-5 | 2-3-1 | 5 PTS | KeyBank Center · Buffalo, NY |
| 7 | Tue Oct 26 | atPenguins | W5-1 | 3-3-1 | 7 PTS | PPG Paints Arena · Pittsburgh, PA |
| 8 | Thu Oct 28 | vsCoyotes | W5-1 | 4-3-1 | 9 PTS | AMALIE Arena · Tampa, FL |
| 9 | Mon Nov 1 | vsCapitals | W3-2 | 5-3-1 | 11 PTS | AMALIE Arena · Tampa, FL |
| 10 | Thu Nov 4 | atMaple Leafs | L1-2 (OT) | 5-3-2 | 12 PTS | Scotiabank Arena · Toronto, ON |
| 11 | Sat Nov 6 | atSenators | W5-3 | 6-3-2 | 14 PTS | Canadian Tire Centre · Ottawa, ON |
| 12 | Tue Nov 9 | vsHurricanes | L1-2 (OT) | 6-3-3 | 15 PTS | AMALIE Arena · Tampa, FL |
| 13 | Sat Nov 13 | vsPanthers | W3-2 (OT) | 7-3-3 | 17 PTS | AMALIE Arena · Tampa, FL |
| 14 | Mon Nov 15 | vsIslanders | W4-1 | 8-3-3 | 19 PTS | AMALIE Arena · Tampa, FL |
| 15 | Thu Nov 18 | atFlyers | W4-3 (SO) | 9-3-3 | 21 PTS | Wells Fargo Center · Philadelphia, PA |
| 16 | Sat Nov 20 | vsDevils | L3-5 | 9-4-3 | 21 PTS | AMALIE Arena · Tampa, FL |
| 17 | Sun Nov 21 | vsWild | W5-4 (SO) | 10-4-3 | 23 PTS | AMALIE Arena · Tampa, FL |
| 18 | Tue Nov 23 | vsFlyers | W4-0 | 11-4-3 | 25 PTS | AMALIE Arena · Tampa, FL |
| 19 | Fri Nov 26 | vsKraken | W3-0 | 12-4-3 | 27 PTS | AMALIE Arena · Tampa, FL |
| 20 | Sun Nov 28 | atWild | L2-4 | 12-5-3 | 27 PTS | Xcel Energy Center · St. Paul, MN |
| 21 | Tue Nov 30 | atBlues | L3-4 (SO) | 12-5-4 | 28 PTS | Enterprise Center · St. Louis, MO |
| 22 | Thu Dec 2 | vsBlues | W4-2 | 13-5-4 | 30 PTS | AMALIE Arena · Tampa, FL |
| 23 | Sat Dec 4 | atBruins | W3-2 (OT) | 14-5-4 | 32 PTS | TD Garden · Boston, MA |
| 24 | Sun Dec 5 | atFlyers | W7-1 | 15-5-4 | 34 PTS | Wells Fargo Center · Philadelphia, PA |
| 25 | Tue Dec 7 | atCanadiens | W3-2 | 16-5-4 | 36 PTS | Bell Centre · Montreal, QC |
| 26 | Thu Dec 9 | atMaple Leafs | W5-3 | 17-5-4 | 38 PTS | Scotiabank Arena · Toronto, ON |
| 27 | Sat Dec 11 | atSenators | L0-4 | 17-6-4 | 38 PTS | Canadian Tire Centre · Ottawa, ON |
| 28 | Tue Dec 14 | vsKings | W3-2 (OT) | 18-6-4 | 40 PTS | AMALIE Arena · Tampa, FL |
| 29 | Thu Dec 16 | vsSenators | W2-1 | 19-6-4 | 42 PTS | AMALIE Arena · Tampa, FL |
| 30 | Tue Dec 21 | atKnights | W4-3 | 20-6-4 | 44 PTS | T-Mobile Arena · Las Vegas, NV |
| 31 | Tue Dec 28 | vsCanadiens | W5-4 (OT) | 21-6-4 | 46 PTS | AMALIE Arena · Tampa, FL |
| 32 | Thu Dec 30 | atPanthers | L3-9 | 21-7-4 | 46 PTS | Amerant Bank Arena · Sunrise, FL |
| 33 | Fri Dec 31 | vsRangers | L3-4 (SO) | 21-7-5 | 47 PTS | AMALIE Arena · Tampa, FL |
| 34 | Sun Jan 2 | atRangers | L0-4 | 21-8-5 | 47 PTS | Madison Square Garden · Manhattan, NY |
| 35 | Tue Jan 4 | atJackets | W7-2 | 22-8-5 | 49 PTS | Nationwide Arena · Columbus, OH |
| 36 | Thu Jan 6 | vsFlames | W4-1 | 23-8-5 | 51 PTS | AMALIE Arena · Tampa, FL |
| 37 | Sat Jan 8 | vsBruins | L2-5 | 23-9-5 | 51 PTS | AMALIE Arena · Tampa, FL |
| 38 | Tue Jan 11 | atSabres | W6-1 | 24-9-5 | 53 PTS | KeyBank Center · Buffalo, NY |
| 39 | Thu Jan 13 | vsCanucks | W4-2 | 25-9-5 | 55 PTS | AMALIE Arena · Tampa, FL |
| 40 | Sat Jan 15 | vsStars | W3-1 | 26-9-5 | 57 PTS | AMALIE Arena · Tampa, FL |
| 41 | Tue Jan 18 | atKings | W6-4 | 27-9-5 | 59 PTS | Crypto.com Arena · Los Angeles, CA |
| 42 | Fri Jan 21 | atDucks | L1-5 | 27-10-5 | 59 PTS | Honda Center · Anaheim, CA |
| 43 | Sat Jan 22 | atSharks | W7-1 | 28-10-5 | 61 PTS | SAP Center · San Jose, CA |
| 44 | Thu Jan 27 | vsDevils | W3-2 | 29-10-5 | 63 PTS | AMALIE Arena · Tampa, FL |
| 45 | Sat Jan 29 | vsKnights | L2-3 (SO) | 29-10-6 | 64 PTS | AMALIE Arena · Tampa, FL |
| 46 | Tue Feb 1 | vsSharks | W3-2 (OT) | 30-10-6 | 66 PTS | AMALIE Arena · Tampa, FL |
| 47 | Thu Feb 10 | atAvalanche | L2-3 | 30-11-6 | 66 PTS | Ball Arena · Denver, CO |
| 48 | Fri Feb 11 | atCoyotes | W4-3 | 31-11-6 | 68 PTS | Mullett Arena · Tempe, AZ |
| 49 | Tue Feb 15 | atDevils | W6-3 | 32-11-6 | 70 PTS | Prudential Center · Newark, NJ |
| 50 | Wed Feb 23 | vsOilers | W5-3 | 33-11-6 | 72 PTS | AMALIE Arena · Tampa, FL |
| 51 | Sat Feb 26 | atPredators | W3-2 | 34-11-6 | 74 PTS | Bridgestone Arena · Nashville, TN |
| 52 | Tue Mar 1 | vsSenators | W5-2 | 35-11-6 | 76 PTS | AMALIE Arena · Tampa, FL |
| 53 | Thu Mar 3 | vsPenguins | L1-5 | 35-12-6 | 76 PTS | AMALIE Arena · Tampa, FL |
| 54 | Fri Mar 4 | vsRed Wings | W3-1 | 36-12-6 | 78 PTS | AMALIE Arena · Tampa, FL |
| 55 | Sun Mar 6 | atBlackhawks | W6-3 | 37-12-6 | 80 PTS | United Center · Chicago, IL |
| 56 | Tue Mar 8 | atJets | L4-7 | 37-13-6 | 80 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 57 | Thu Mar 10 | atFlames | L1-4 | 37-14-6 | 80 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 58 | Sat Mar 12 | atOilers | L1-4 | 37-15-6 | 80 PTS | Rogers Place · Edmonton, AB |
| 59 | Sun Mar 13 | atCanucks | W2-1 | 38-15-6 | 82 PTS | Rogers Arena · Vancouver, British Columbia |
| 60 | Wed Mar 16 | atKraken | W4-1 | 39-15-6 | 84 PTS | Climate Pledge Arena · Seattle, WA |
| 61 | Sat Mar 19 | vsRangers | L1-2 | 39-16-6 | 84 PTS | AMALIE Arena · Tampa, FL |
| 62 | Tue Mar 22 | atHurricanes | L2-3 | 39-17-6 | 84 PTS | PNC Arena · Raleigh, NC |
| 63 | Thu Mar 24 | atBruins | L2-3 | 39-18-6 | 84 PTS | TD Garden · Boston, MA |
| 64 | Sat Mar 26 | atRed Wings | W2-1 (OT) | 40-18-6 | 86 PTS | Little Caesars Arena · Detroit, MI |
| 65 | Sun Mar 27 | atIslanders | W4-1 | 41-18-6 | 88 PTS | UBS Arena · Elmont, NY |
| 66 | Tue Mar 29 | vsHurricanes | W4-3 (OT) | 42-18-6 | 90 PTS | AMALIE Arena · Tampa, FL |
| 67 | Fri Apr 1 | vsBlackhawks | W5-2 | 43-18-6 | 92 PTS | AMALIE Arena · Tampa, FL |
| 68 | Sat Apr 2 | vsCanadiens | L4-5 (SO) | 43-18-7 | 93 PTS | AMALIE Arena · Tampa, FL |
| 69 | Mon Apr 4 | vsMaple Leafs | L2-6 | 43-19-7 | 93 PTS | AMALIE Arena · Tampa, FL |
| 70 | Wed Apr 6 | atCapitals | L3-4 | 43-20-7 | 93 PTS | Capital One Arena · Washington, D.C. |
| 71 | Fri Apr 8 | vsBruins | L1-2 (OT) | 43-20-8 | 94 PTS | AMALIE Arena · Tampa, FL |
| 72 | Sun Apr 10 | vsSabres | W5-0 | 44-20-8 | 96 PTS | AMALIE Arena · Tampa, FL |
| 73 | Tue Apr 12 | atStars | L0-1 | 44-21-8 | 96 PTS | American Airlines Center · Dallas, TX |
| 74 | Thu Apr 14 | vsDucks | W4-3 (OT) | 45-21-8 | 98 PTS | AMALIE Arena · Tampa, FL |
| 75 | Sat Apr 16 | vsJets | W7-4 | 46-21-8 | 100 PTS | AMALIE Arena · Tampa, FL |
| 76 | Tue Apr 19 | vsRed Wings | L3-4 | 46-22-8 | 100 PTS | AMALIE Arena · Tampa, FL |
| 77 | Thu Apr 21 | vsMaple Leafs | W8-1 | 47-22-8 | 102 PTS | AMALIE Arena · Tampa, FL |
| 78 | Sat Apr 23 | vsPredators | W6-2 | 48-22-8 | 104 PTS | AMALIE Arena · Tampa, FL |
| 79 | Sun Apr 24 | atPanthers | W8-4 | 49-22-8 | 106 PTS | Amerant Bank Arena · Sunrise, FL |
| 80 | Tue Apr 26 | vsJackets | W4-1 | 50-22-8 | 108 PTS | AMALIE Arena · Tampa, FL |
| 81 | Thu Apr 28 | atJackets | L2-5 | 50-23-8 | 108 PTS | Nationwide Arena · Columbus, OH |
| 82 | Fri Apr 29 | atIslanders | W6-4 | 51-23-8 | 110 PTS | UBS Arena · Elmont, NY |
| 1 | Mon May 2 | atMaple Leafs | L0-5 | 0-1 | .000 | Scotiabank Arena · Toronto, ON |
| 2 | Wed May 4 | atMaple Leafs | W5-3 | 1-1 | .500 | Scotiabank Arena · Toronto, ON |
| 3 | Fri May 6 | vsMaple Leafs | L2-5 | 1-2 | .333 | AMALIE Arena · Tampa, FL |
| 4 | Sun May 8 | vsMaple Leafs | W7-3 | 2-2 | .500 | AMALIE Arena · Tampa, FL |
| 5 | Tue May 10 | atMaple Leafs | L3-4 | 2-3 | .400 | Scotiabank Arena · Toronto, ON |
| 6 | Thu May 12 | vsMaple Leafs | W4-3 (OT) | 3-3 | .500 | AMALIE Arena · Tampa, FL |
| 7 | Sat May 14 | atMaple Leafs | W2-1 | 4-3 | .571 | Scotiabank Arena · Toronto, ON |
| 1 | Tue May 17 | atPanthers | W4-1 | 1-0 | 1.000 | Amerant Bank Arena · Sunrise, FL |
| 2 | Thu May 19 | atPanthers | W2-1 | 2-0 | 1.000 | Amerant Bank Arena · Sunrise, FL |
| 3 | Sun May 22 | vsPanthers | W5-1 | 3-0 | 1.000 | AMALIE Arena · Tampa, FL |
| 4 | Mon May 23 | vsPanthers | W2-0 | 4-0 | 1.000 | AMALIE Arena · Tampa, FL |
| 1 | Wed Jun 1 | atRangers | L2-6 | 0-1 | .000 | Madison Square Garden · Manhattan, NY |
| 2 | Fri Jun 3 | atRangers | L2-3 | 0-2 | .000 | Madison Square Garden · Manhattan, NY |
| 3 | Sun Jun 5 | vsRangers | W3-2 | 1-2 | .333 | AMALIE Arena · Tampa, FL |
| 4 | Tue Jun 7 | vsRangers | W4-1 | 2-2 | .500 | AMALIE Arena · Tampa, FL |
| 5 | Thu Jun 9 | atRangers | W3-1 | 3-2 | .600 | Madison Square Garden · Manhattan, NY |
| 6 | Sat Jun 11 | vsRangers | W2-1 | 4-2 | .667 | AMALIE Arena · Tampa, FL |
| 1 | Wed Jun 15 | atAvalanche | L3-4 (OT) | 0-1 | .000 | Ball Arena · Denver, CO |
| 2 | Sat Jun 18 | atAvalanche | L0-7 | 0-2 | .000 | Ball Arena · Denver, CO |
| 3 | Mon Jun 20 | vsAvalanche | W6-2 | 1-2 | .333 | AMALIE Arena · Tampa, FL |
| 4 | Wed Jun 22 | vsAvalanche | L2-3 (OT) | 1-3 | .250 | AMALIE Arena · Tampa, FL |
| 5 | Fri Jun 24 | atAvalanche | W3-2 | 2-3 | .400 | Ball Arena · Denver, CO |
| 6 | Sun Jun 26 | vsAvalanche | L1-2 | 2-4 | .333 | AMALIE Arena · Tampa, FL |
