| 1 | Tue Oct 10 | vs Predators | W5-3 | 1-0-0 | 2 PTS | AMALIE Arena · Tampa, FL |
| 2 | Sat Oct 14 | atRed Wings | L4-6 | 1-1-0 | 2 PTS | Little Caesars Arena · Detroit, MI |
| 3 | Sun Oct 15 | atSenators | L2-5 | 1-2-0 | 2 PTS | Canadian Tire Centre · Ottawa, ON |
| 4 | Tue Oct 17 | atSabres | L2-3 (OT) | 1-2-1 | 3 PTS | KeyBank Center · Buffalo, NY |
| 5 | Thu Oct 19 | vsCanucks | W4-3 | 2-2-1 | 5 PTS | AMALIE Arena · Tampa, FL |
| 6 | Sat Oct 21 | vsMaple Leafs | L3-4 (OT) | 2-2-2 | 6 PTS | AMALIE Arena · Tampa, FL |
| 7 | Tue Oct 24 | vsHurricanes | W3-0 | 3-2-2 | 8 PTS | AMALIE Arena · Tampa, FL |
| 8 | Thu Oct 26 | vsSharks | W6-0 | 4-2-2 | 10 PTS | AMALIE Arena · Tampa, FL |
| 9 | Mon Oct 30 | vsKraken | L3-4 (OT) | 4-2-3 | 11 PTS | AMALIE Arena · Tampa, FL |
| 10 | Thu Nov 2 | atJackets | L2-4 | 4-3-3 | 11 PTS | Nationwide Arena · Columbus, OH |
| 11 | Sat Nov 4 | atSenators | W6-4 | 5-3-3 | 13 PTS | Canadian Tire Centre · Ottawa, ON |
| 12 | Mon Nov 6 | atMaple Leafs | L5-6 (OT) | 5-3-4 | 14 PTS | Scotiabank Arena · Toronto, ON |
| 13 | Tue Nov 7 | atCanadiens | W5-3 | 6-3-4 | 16 PTS | Bell Centre · Montreal, QC |
| 14 | Thu Nov 9 | vsBlackhawks | L3-5 | 6-4-4 | 16 PTS | AMALIE Arena · Tampa, FL |
| 15 | Sat Nov 11 | vsHurricanes | L0-4 | 6-5-4 | 16 PTS | AMALIE Arena · Tampa, FL |
| 16 | Tue Nov 14 | atBlues | L0-5 | 6-6-4 | 16 PTS | Enterprise Center · St. Louis, MO |
| 17 | Thu Nov 16 | atBlackhawks | W4-2 | 7-6-4 | 18 PTS | United Center · Chicago, IL |
| 18 | Sat Nov 18 | vsOilers | W6-4 | 8-6-4 | 20 PTS | AMALIE Arena · Tampa, FL |
| 19 | Mon Nov 20 | vsBruins | W5-4 (OT) | 9-6-4 | 22 PTS | AMALIE Arena · Tampa, FL |
| 20 | Wed Nov 22 | vsJets | L2-3 (OT) | 9-6-5 | 23 PTS | AMALIE Arena · Tampa, FL |
| 21 | Fri Nov 24 | atHurricanes | W8-2 | 10-6-5 | 25 PTS | PNC Arena · Raleigh, NC |
| 22 | Mon Nov 27 | atAvalanche | L1-4 | 10-7-5 | 25 PTS | Ball Arena · Denver, CO |
| 23 | Tue Nov 28 | atCoyotes | L1-3 | 10-8-5 | 25 PTS | Mullett Arena · Tempe, AZ |
| 24 | Thu Nov 30 | vsPenguins | L2-4 | 10-9-5 | 25 PTS | AMALIE Arena · Tampa, FL |
| 25 | Sat Dec 2 | atStars | L1-8 | 10-10-5 | 25 PTS | American Airlines Center · Dallas, TX |
| 26 | Mon Dec 4 | vsStars | W4-0 | 11-10-5 | 27 PTS | AMALIE Arena · Tampa, FL |
| 27 | Wed Dec 6 | vsPenguins | W3-1 | 12-10-5 | 29 PTS | AMALIE Arena · Tampa, FL |
| 28 | Thu Dec 7 | atPredators | L1-5 | 12-11-5 | 29 PTS | Bridgestone Arena · Nashville, TN |
| 29 | Sat Dec 9 | atKraken | W4-3 (OT) | 13-11-5 | 31 PTS | Climate Pledge Arena · Seattle, WA |
| 30 | Tue Dec 12 | atCanucks | L1-4 | 13-12-5 | 31 PTS | Rogers Arena · Vancouver, British Columbia |
| 31 | Thu Dec 14 | atOilers | W7-4 | 14-12-5 | 33 PTS | Rogers Place · Edmonton, AB |
| 32 | Sat Dec 16 | atFlames | L2-4 | 14-13-5 | 33 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 33 | Tue Dec 19 | vsBlues | W6-1 | 15-13-5 | 35 PTS | AMALIE Arena · Tampa, FL |
| 34 | Thu Dec 21 | vsKnights | W5-4 | 16-13-5 | 37 PTS | AMALIE Arena · Tampa, FL |
| 35 | Sat Dec 23 | atCapitals | W2-1 (SO) | 17-13-5 | 39 PTS | Capital One Arena · Washington, D.C. |
| 36 | Wed Dec 27 | vsPanthers | L2-3 | 17-14-5 | 39 PTS | AMALIE Arena · Tampa, FL |
| 37 | Sat Dec 30 | vsRangers | L1-5 | 17-15-5 | 39 PTS | AMALIE Arena · Tampa, FL |
| 38 | Sun Dec 31 | vsCanadiens | W4-3 | 18-15-5 | 41 PTS | AMALIE Arena · Tampa, FL |
| 39 | Tue Jan 2 | atJets | L2-4 | 18-16-5 | 41 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 40 | Thu Jan 4 | atWild | W4-1 | 19-16-5 | 43 PTS | Xcel Energy Center · St. Paul, MN |
| 41 | Sat Jan 6 | atBruins | L3-7 | 19-17-5 | 43 PTS | TD Garden · Boston, MA |
| 42 | Tue Jan 9 | vsKings | W3-2 (OT) | 20-17-5 | 45 PTS | AMALIE Arena · Tampa, FL |
| 43 | Thu Jan 11 | vsDevils | W4-3 (OT) | 21-17-5 | 47 PTS | AMALIE Arena · Tampa, FL |
| 44 | Sat Jan 13 | vsDucks | W5-1 | 22-17-5 | 49 PTS | AMALIE Arena · Tampa, FL |
| 45 | Thu Jan 18 | vsWild | W7-3 | 23-17-5 | 51 PTS | AMALIE Arena · Tampa, FL |
| 46 | Sat Jan 20 | atSabres | W3-1 | 24-17-5 | 53 PTS | KeyBank Center · Buffalo, NY |
| 47 | Sun Jan 21 | atRed Wings | L1-2 | 24-18-5 | 53 PTS | Little Caesars Arena · Detroit, MI |
| 48 | Tue Jan 23 | atFlyers | W6-3 | 25-18-5 | 55 PTS | Wells Fargo Center · Philadelphia, PA |
| 49 | Thu Jan 25 | vsCoyotes | W6-3 | 26-18-5 | 57 PTS | AMALIE Arena · Tampa, FL |
| 50 | Sat Jan 27 | vsDevils | W6-3 | 27-18-5 | 59 PTS | AMALIE Arena · Tampa, FL |
| 51 | Wed Feb 7 | atRangers | L1-3 | 27-19-5 | 59 PTS | Madison Square Garden · Manhattan, NY |
| 52 | Thu Feb 8 | atIslanders | L2-6 | 27-20-5 | 59 PTS | UBS Arena · Elmont, NY |
| 53 | Sat Feb 10 | atJackets | W4-2 | 28-20-5 | 61 PTS | Nationwide Arena · Columbus, OH |
| 54 | Tue Feb 13 | atBruins | W3-2 (SO) | 29-20-5 | 63 PTS | TD Garden · Boston, MA |
| 55 | Thu Feb 15 | vsAvalanche | W6-3 | 30-20-5 | 65 PTS | AMALIE Arena · Tampa, FL |
| 56 | Sat Feb 17 | vsPanthers | L2-9 | 30-21-5 | 65 PTS | AMALIE Arena · Tampa, FL |
| 57 | Mon Feb 19 | vsSenators | L2-4 | 30-22-5 | 65 PTS | AMALIE Arena · Tampa, FL |
| 58 | Thu Feb 22 | vsCapitals | L3-5 | 30-23-5 | 65 PTS | AMALIE Arena · Tampa, FL |
| 59 | Sat Feb 24 | atIslanders | W4-2 | 31-23-5 | 67 PTS | UBS Arena · Elmont, NY |
| 60 | Sun Feb 25 | atDevils | W4-1 | 32-23-5 | 69 PTS | Prudential Center · Newark, NJ |
| 61 | Tue Feb 27 | atFlyers | L2-6 | 32-24-5 | 69 PTS | Wells Fargo Center · Philadelphia, PA |
| 62 | Thu Feb 29 | vsSabres | L2-3 (OT) | 32-24-6 | 70 PTS | AMALIE Arena · Tampa, FL |
| 63 | Sat Mar 2 | vsCanadiens | W4-3 (SO) | 33-24-6 | 72 PTS | AMALIE Arena · Tampa, FL |
| 64 | Thu Mar 7 | vsFlames | L3-6 | 33-25-6 | 72 PTS | AMALIE Arena · Tampa, FL |
| 65 | Sat Mar 9 | vsFlyers | W7-0 | 34-25-6 | 74 PTS | AMALIE Arena · Tampa, FL |
| 66 | Thu Mar 14 | vsRangers | W6-3 | 35-25-6 | 76 PTS | AMALIE Arena · Tampa, FL |
| 67 | Sat Mar 16 | atPanthers | W5-3 | 36-25-6 | 78 PTS | Amerant Bank Arena · Sunrise, FL |
| 68 | Tue Mar 19 | atKnights | W5-3 | 37-25-6 | 80 PTS | T-Mobile Arena · Las Vegas, NV |
| 69 | Thu Mar 21 | atSharks | W4-1 | 38-25-6 | 82 PTS | SAP Center · San Jose, CA |
| 70 | Sat Mar 23 | atKings | L3-4 (OT) | 38-25-7 | 83 PTS | Crypto.com Arena · Los Angeles, CA |
| 71 | Sun Mar 24 | atDucks | W3-2 (OT) | 39-25-7 | 85 PTS | Honda Center · Anaheim, CA |
| 72 | Wed Mar 27 | vsBruins | W3-1 | 40-25-7 | 87 PTS | AMALIE Arena · Tampa, FL |
| 73 | Sat Mar 30 | vsIslanders | W4-1 | 41-25-7 | 89 PTS | AMALIE Arena · Tampa, FL |
| 74 | Mon Apr 1 | vsRed Wings | L2-4 | 41-26-7 | 89 PTS | AMALIE Arena · Tampa, FL |
| 75 | Wed Apr 3 | atMaple Leafs | W4-1 | 42-26-7 | 91 PTS | Scotiabank Arena · Toronto, ON |
| 76 | Thu Apr 4 | atCanadiens | W7-4 | 43-26-7 | 93 PTS | Bell Centre · Montreal, QC |
| 77 | Sat Apr 6 | atPenguins | L4-5 | 43-27-7 | 93 PTS | PPG Paints Arena · Pittsburgh, PA |
| 78 | Tue Apr 9 | vsJackets | W5-2 | 44-27-7 | 95 PTS | AMALIE Arena · Tampa, FL |
| 79 | Thu Apr 11 | vsSenators | L2-3 (SO) | 44-27-8 | 96 PTS | AMALIE Arena · Tampa, FL |
| 80 | Sat Apr 13 | atCapitals | L2-4 | 44-28-8 | 96 PTS | Capital One Arena · Washington, D.C. |
| 81 | Mon Apr 15 | vsSabres | L2-4 | 44-29-8 | 96 PTS | AMALIE Arena · Tampa, FL |
| 82 | Wed Apr 17 | vsMaple Leafs | W6-4 | 45-29-8 | 98 PTS | AMALIE Arena · Tampa, FL |
| 1 | Sun Apr 21 | atPanthers | L2-3 | 0-1 | .000 | Amerant Bank Arena · Sunrise, FL |
| 2 | Tue Apr 23 | atPanthers | L2-3 (OT) | 0-2 | .000 | Amerant Bank Arena · Sunrise, FL |
| 3 | Thu Apr 25 | vsPanthers | L3-5 | 0-3 | .000 | AMALIE Arena · Tampa, FL |
| 4 | Sat Apr 27 | vsPanthers | W6-3 | 1-3 | .250 | AMALIE Arena · Tampa, FL |
| 5 | Mon Apr 29 | atPanthers | L1-6 | 1-4 | .200 | Amerant Bank Arena · Sunrise, FL |
