| 1 | Tue Oct 11 | at Kings | W4-3 | 1-0-0 | 2 PTS | Crypto.com Arena · Los Angeles, CA |
| 2 | Thu Oct 13 | vsBlackhawks | W1-0 | 2-0-0 | 4 PTS | T-Mobile Arena · Las Vegas, NV |
| 3 | Sat Oct 15 | atKraken | W5-2 | 3-0-0 | 6 PTS | Climate Pledge Arena · Seattle, WA |
| 4 | Tue Oct 18 | atFlames | L2-3 | 3-1-0 | 6 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 5 | Thu Oct 20 | vsJets | W5-2 | 4-1-0 | 8 PTS | T-Mobile Arena · Las Vegas, NV |
| 6 | Sat Oct 22 | vsAvalanche | L2-3 | 4-2-0 | 8 PTS | T-Mobile Arena · Las Vegas, NV |
| 7 | Mon Oct 24 | vsMaple Leafs | W3-1 | 5-2-0 | 10 PTS | T-Mobile Arena · Las Vegas, NV |
| 8 | Tue Oct 25 | atSharks | W4-2 | 6-2-0 | 12 PTS | SAP Center · San Jose, CA |
| 9 | Fri Oct 28 | vsDucks | W4-0 | 7-2-0 | 14 PTS | T-Mobile Arena · Las Vegas, NV |
| 10 | Sun Oct 30 | vsJets | W2-1 (OT) | 8-2-0 | 16 PTS | T-Mobile Arena · Las Vegas, NV |
| 11 | Tue Nov 1 | atCapitals | W3-2 (OT) | 9-2-0 | 18 PTS | Capital One Arena · Washington, D.C. |
| 12 | Thu Nov 3 | atSenators | W5-4 | 10-2-0 | 20 PTS | Canadian Tire Centre · Ottawa, ON |
| 13 | Sat Nov 5 | atCanadiens | W6-4 | 11-2-0 | 22 PTS | Bell Centre · Montreal, QC |
| 14 | Tue Nov 8 | atMaple Leafs | W4-3 (OT) | 12-2-0 | 24 PTS | Scotiabank Arena · Toronto, ON |
| 15 | Thu Nov 10 | atSabres | W7-4 | 13-2-0 | 26 PTS | KeyBank Center · Buffalo, NY |
| 16 | Sat Nov 12 | vsBlues | L2-3 | 13-3-0 | 26 PTS | T-Mobile Arena · Las Vegas, NV |
| 17 | Tue Nov 15 | vsSharks | L2-5 | 13-4-0 | 26 PTS | T-Mobile Arena · Las Vegas, NV |
| 18 | Thu Nov 17 | vsCoyotes | W4-1 | 14-4-0 | 28 PTS | T-Mobile Arena · Las Vegas, NV |
| 19 | Sat Nov 19 | atOilers | L3-4 (OT) | 14-4-1 | 29 PTS | Rogers Place · Edmonton, AB |
| 20 | Mon Nov 21 | atCanucks | W5-4 | 15-4-1 | 31 PTS | Rogers Arena · Vancouver, British Columbia |
| 21 | Wed Nov 23 | vsSenators | W4-1 | 16-4-1 | 33 PTS | T-Mobile Arena · Las Vegas, NV |
| 22 | Fri Nov 25 | vsKraken | L2-4 | 16-5-1 | 33 PTS | T-Mobile Arena · Las Vegas, NV |
| 23 | Sat Nov 26 | vsCanucks | L1-5 | 16-6-1 | 33 PTS | T-Mobile Arena · Las Vegas, NV |
| 24 | Mon Nov 28 | atJackets | W3-2 (SO) | 17-6-1 | 35 PTS | Nationwide Arena · Columbus, OH |
| 25 | Thu Dec 1 | atPenguins | L3-4 | 17-7-1 | 35 PTS | PPG Paints Arena · Pittsburgh, PA |
| 26 | Sat Dec 3 | atRed Wings | W4-1 | 18-7-1 | 37 PTS | Little Caesars Arena · Detroit, MI |
| 27 | Mon Dec 5 | atBruins | W4-3 (SO) | 19-7-1 | 39 PTS | TD Garden · Boston, MA |
| 28 | Wed Dec 7 | vsRangers | L1-5 | 19-8-1 | 39 PTS | T-Mobile Arena · Las Vegas, NV |
| 29 | Fri Dec 9 | vsFlyers | W2-1 (OT) | 20-8-1 | 41 PTS | T-Mobile Arena · Las Vegas, NV |
| 30 | Sun Dec 11 | vsBruins | L1-3 | 20-9-1 | 41 PTS | T-Mobile Arena · Las Vegas, NV |
| 31 | Tue Dec 13 | atJets | W6-5 | 21-9-1 | 43 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 32 | Thu Dec 15 | atBlackhawks | W4-1 | 22-9-1 | 45 PTS | United Center · Chicago, IL |
| 33 | Sat Dec 17 | vsIslanders | L2-5 | 22-10-1 | 45 PTS | T-Mobile Arena · Las Vegas, NV |
| 34 | Mon Dec 19 | vsSabres | L2-3 | 22-11-1 | 45 PTS | T-Mobile Arena · Las Vegas, NV |
| 35 | Wed Dec 21 | vsCoyotes | W5-2 | 23-11-1 | 47 PTS | T-Mobile Arena · Las Vegas, NV |
| 36 | Fri Dec 23 | vsBlues | W5-4 (SO) | 24-11-1 | 49 PTS | T-Mobile Arena · Las Vegas, NV |
| 37 | Tue Dec 27 | atKings | L2-4 | 24-12-1 | 49 PTS | Crypto.com Arena · Los Angeles, CA |
| 38 | Wed Dec 28 | atDucks | L2-3 (SO) | 24-12-2 | 50 PTS | Honda Center · Anaheim, CA |
| 39 | Sat Dec 31 | vsPredators | W5-4 (OT) | 25-12-2 | 52 PTS | T-Mobile Arena · Las Vegas, NV |
| 40 | Mon Jan 2 | atAvalanche | W3-2 | 26-12-2 | 54 PTS | Ball Arena · Denver, CO |
| 41 | Thu Jan 5 | vsPenguins | W5-2 | 27-12-2 | 56 PTS | T-Mobile Arena · Las Vegas, NV |
| 42 | Sat Jan 7 | vsKings | L1-5 | 27-13-2 | 56 PTS | T-Mobile Arena · Las Vegas, NV |
| 43 | Thu Jan 12 | vsPanthers | W4-2 | 28-13-2 | 58 PTS | T-Mobile Arena · Las Vegas, NV |
| 44 | Sat Jan 14 | vsOilers | L3-4 | 28-14-2 | 58 PTS | T-Mobile Arena · Las Vegas, NV |
| 45 | Mon Jan 16 | vsStars | L0-4 | 28-15-2 | 58 PTS | T-Mobile Arena · Las Vegas, NV |
| 46 | Thu Jan 19 | vsRed Wings | L2-3 | 28-16-2 | 58 PTS | T-Mobile Arena · Las Vegas, NV |
| 47 | Sat Jan 21 | vsCapitals | W6-2 | 29-16-2 | 60 PTS | T-Mobile Arena · Las Vegas, NV |
| 48 | Sun Jan 22 | atCoyotes | L1-4 | 29-17-2 | 60 PTS | Mullett Arena · Tempe, AZ |
| 49 | Tue Jan 24 | atDevils | L2-3 (OT) | 29-17-3 | 61 PTS | Prudential Center · Newark, NJ |
| 50 | Fri Jan 27 | atRangers | L1-4 | 29-18-3 | 61 PTS | Madison Square Garden · Manhattan, NY |
| 51 | Sat Jan 28 | atIslanders | L1-2 (OT) | 29-18-4 | 62 PTS | UBS Arena · Elmont, NY |
| 52 | Tue Feb 7 | atPredators | W5-1 | 30-18-4 | 64 PTS | Bridgestone Arena · Nashville, TN |
| 53 | Thu Feb 9 | atWild | W5-1 | 31-18-4 | 66 PTS | Xcel Energy Center · St. Paul, MN |
| 54 | Sun Feb 12 | vsDucks | W7-2 | 32-18-4 | 68 PTS | T-Mobile Arena · Las Vegas, NV |
| 55 | Thu Feb 16 | vsSharks | W2-1 | 33-18-4 | 70 PTS | T-Mobile Arena · Las Vegas, NV |
| 56 | Sat Feb 18 | vsLightning | W5-4 | 34-18-4 | 72 PTS | T-Mobile Arena · Las Vegas, NV |
| 57 | Tue Feb 21 | atBlackhawks | L2-3 (SO) | 34-18-5 | 73 PTS | United Center · Chicago, IL |
| 58 | Thu Feb 23 | vsFlames | W4-3 (OT) | 35-18-5 | 75 PTS | T-Mobile Arena · Las Vegas, NV |
| 59 | Sat Feb 25 | vsStars | L2-3 (SO) | 35-18-6 | 76 PTS | T-Mobile Arena · Las Vegas, NV |
| 60 | Mon Feb 27 | atAvalanche | L0-3 | 35-19-6 | 76 PTS | Ball Arena · Denver, CO |
| 61 | Wed Mar 1 | vsHurricanes | W3-2 | 36-19-6 | 78 PTS | T-Mobile Arena · Las Vegas, NV |
| 62 | Fri Mar 3 | vsDevils | W4-3 (SO) | 37-19-6 | 80 PTS | T-Mobile Arena · Las Vegas, NV |
| 63 | Sun Mar 5 | vsCanadiens | W4-3 | 38-19-6 | 82 PTS | T-Mobile Arena · Las Vegas, NV |
| 64 | Tue Mar 7 | atPanthers | L1-2 | 38-20-6 | 82 PTS | Amerant Bank Arena · Sunrise, FL |
| 65 | Thu Mar 9 | atLightning | W4-3 (OT) | 39-20-6 | 84 PTS | AMALIE Arena · Tampa, FL |
| 66 | Sat Mar 11 | atHurricanes | W4-0 | 40-20-6 | 86 PTS | PNC Arena · Raleigh, NC |
| 67 | Sun Mar 12 | atBlues | W5-3 | 41-20-6 | 88 PTS | Enterprise Center · St. Louis, MO |
| 68 | Tue Mar 14 | atFlyers | W5-3 | 42-20-6 | 90 PTS | Wells Fargo Center · Philadelphia, PA |
| 69 | Thu Mar 16 | vsFlames | L2-7 | 42-21-6 | 90 PTS | T-Mobile Arena · Las Vegas, NV |
| 70 | Sun Mar 19 | vsJackets | W7-2 | 43-21-6 | 92 PTS | T-Mobile Arena · Las Vegas, NV |
| 71 | Tue Mar 21 | atCanucks | W4-3 | 44-21-6 | 94 PTS | Rogers Arena · Vancouver, British Columbia |
| 72 | Thu Mar 23 | atFlames | W3-2 | 45-21-6 | 96 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 73 | Sat Mar 25 | atOilers | W4-3 (OT) | 46-21-6 | 98 PTS | Rogers Place · Edmonton, AB |
| 74 | Tue Mar 28 | vsOilers | L4-7 | 46-22-6 | 98 PTS | T-Mobile Arena · Las Vegas, NV |
| 75 | Thu Mar 30 | atSharks | L3-4 (OT) | 46-22-7 | 99 PTS | SAP Center · San Jose, CA |
| 76 | Sat Apr 1 | vsWild | W4-1 | 47-22-7 | 101 PTS | T-Mobile Arena · Las Vegas, NV |
| 77 | Mon Apr 3 | atWild | W4-3 (SO) | 48-22-7 | 103 PTS | Xcel Energy Center · St. Paul, MN |
| 78 | Tue Apr 4 | atPredators | L2-3 (OT) | 48-22-8 | 104 PTS | Bridgestone Arena · Nashville, TN |
| 79 | Thu Apr 6 | vsKings | W5-2 | 49-22-8 | 106 PTS | T-Mobile Arena · Las Vegas, NV |
| 80 | Sat Apr 8 | atStars | L1-2 (SO) | 49-22-9 | 107 PTS | American Airlines Center · Dallas, TX |
| 81 | Tue Apr 11 | vsKraken | W4-1 | 50-22-9 | 109 PTS | T-Mobile Arena · Las Vegas, NV |
| 82 | Thu Apr 13 | atKraken | W3-1 | 51-22-9 | 111 PTS | Climate Pledge Arena · Seattle, WA |
| 1 | Tue Apr 18 | vsJets | L1-5 | 0-1 | .000 | T-Mobile Arena · Las Vegas, NV |
| 2 | Thu Apr 20 | vsJets | W5-2 | 1-1 | .500 | T-Mobile Arena · Las Vegas, NV |
| 3 | Sat Apr 22 | atJets | W5-4 (OT) | 2-1 | .667 | Canada Life Centre · Winnipeg, Manitoba |
| 4 | Mon Apr 24 | atJets | W4-2 | 3-1 | .750 | Canada Life Centre · Winnipeg, Manitoba |
| 5 | Thu Apr 27 | vsJets | W4-1 | 4-1 | .800 | T-Mobile Arena · Las Vegas, NV |
| 1 | Wed May 3 | vsOilers | W6-4 | 1-0 | 1.000 | T-Mobile Arena · Las Vegas, NV |
| 2 | Sat May 6 | vsOilers | L1-5 | 1-1 | .500 | T-Mobile Arena · Las Vegas, NV |
| 3 | Mon May 8 | atOilers | W5-1 | 2-1 | .667 | Rogers Place · Edmonton, AB |
| 4 | Wed May 10 | atOilers | L1-4 | 2-2 | .500 | Rogers Place · Edmonton, AB |
| 5 | Fri May 12 | vsOilers | W4-3 | 3-2 | .600 | T-Mobile Arena · Las Vegas, NV |
| 6 | Sun May 14 | atOilers | W5-2 | 4-2 | .667 | Rogers Place · Edmonton, AB |
| 1 | Fri May 19 | vsStars | W4-3 (OT) | 1-0 | 1.000 | T-Mobile Arena · Las Vegas, NV |
| 2 | Sun May 21 | vsStars | W3-2 (OT) | 2-0 | 1.000 | T-Mobile Arena · Las Vegas, NV |
| 3 | Tue May 23 | atStars | W4-0 | 3-0 | 1.000 | American Airlines Center · Dallas, TX |
| 4 | Thu May 25 | atStars | L2-3 (OT) | 3-1 | .750 | American Airlines Center · Dallas, TX |
| 5 | Sat May 27 | vsStars | L2-4 | 3-2 | .600 | T-Mobile Arena · Las Vegas, NV |
| 6 | Mon May 29 | atStars | W6-0 | 4-2 | .667 | American Airlines Center · Dallas, TX |
| 1 | Sat Jun 3 | vsPanthers | W5-2 | 1-0 | 1.000 | T-Mobile Arena · Las Vegas, NV |
| 2 | Mon Jun 5 | vsPanthers | W7-2 | 2-0 | 1.000 | T-Mobile Arena · Las Vegas, NV |
| 3 | Thu Jun 8 | atPanthers | L2-3 (OT) | 2-1 | .667 | Amerant Bank Arena · Sunrise, FL |
| 4 | Sat Jun 10 | atPanthers | W3-2 | 3-1 | .750 | Amerant Bank Arena · Sunrise, FL |
| 5 | Tue Jun 13 | vsPanthers | W9-3 | 4-1 | .800 | T-Mobile Arena · Las Vegas, NV |
