| 1 | Tue Oct 10 | vs Kraken | W4-1 | 1-0-0 | 2 PTS | T-Mobile Arena · Las Vegas, NV |
| 2 | Thu Oct 12 | atSharks | W4-1 | 2-0-0 | 4 PTS | SAP Center · San Jose, CA |
| 3 | Sat Oct 14 | vsDucks | W4-1 | 3-0-0 | 6 PTS | T-Mobile Arena · Las Vegas, NV |
| 4 | Tue Oct 17 | vsStars | W3-2 (SO) | 4-0-0 | 8 PTS | T-Mobile Arena · Las Vegas, NV |
| 5 | Thu Oct 19 | atJets | W5-3 | 5-0-0 | 10 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 6 | Sat Oct 21 | atBlackhawks | W5-3 | 6-0-0 | 12 PTS | United Center · Chicago, IL |
| 7 | Tue Oct 24 | vsFlyers | W3-2 | 7-0-0 | 14 PTS | T-Mobile Arena · Las Vegas, NV |
| 8 | Fri Oct 27 | vsBlackhawks | L3-4 (OT) | 7-0-1 | 15 PTS | T-Mobile Arena · Las Vegas, NV |
| 9 | Sat Oct 28 | atKings | W4-3 (SO) | 8-0-1 | 17 PTS | Crypto.com Arena · Los Angeles, CA |
| 10 | Mon Oct 30 | vsCanadiens | W3-2 (SO) | 9-0-1 | 19 PTS | T-Mobile Arena · Las Vegas, NV |
| 11 | Thu Nov 2 | vsJets | W5-2 | 10-0-1 | 21 PTS | T-Mobile Arena · Las Vegas, NV |
| 12 | Sat Nov 4 | vsAvalanche | W7-0 | 11-0-1 | 23 PTS | T-Mobile Arena · Las Vegas, NV |
| 13 | Sun Nov 5 | atDucks | L2-4 | 11-1-1 | 23 PTS | Honda Center · Anaheim, CA |
| 14 | Wed Nov 8 | vsKings | L1-4 | 11-2-1 | 23 PTS | T-Mobile Arena · Las Vegas, NV |
| 15 | Fri Nov 10 | vsSharks | W5-0 | 12-2-1 | 25 PTS | T-Mobile Arena · Las Vegas, NV |
| 16 | Tue Nov 14 | atCapitals | L0-3 | 12-3-1 | 25 PTS | Capital One Arena · Washington, D.C. |
| 17 | Thu Nov 16 | atCanadiens | W6-5 | 13-3-1 | 27 PTS | Bell Centre · Montreal, QC |
| 18 | Sat Nov 18 | atFlyers | L3-4 (OT) | 13-3-2 | 28 PTS | Wells Fargo Center · Philadelphia, PA |
| 19 | Sun Nov 19 | atPenguins | L0-3 | 13-4-2 | 28 PTS | PPG Paints Arena · Pittsburgh, PA |
| 20 | Wed Nov 22 | atStars | W2-1 (OT) | 14-4-2 | 30 PTS | American Airlines Center · Dallas, TX |
| 21 | Sat Nov 25 | vsCoyotes | L0-2 | 14-5-2 | 30 PTS | T-Mobile Arena · Las Vegas, NV |
| 22 | Mon Nov 27 | atFlames | L1-2 (OT) | 14-5-3 | 31 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 23 | Tue Nov 28 | atOilers | L4-5 (SO) | 14-5-4 | 32 PTS | Rogers Place · Edmonton, AB |
| 24 | Thu Nov 30 | atCanucks | W4-1 | 15-5-4 | 34 PTS | Rogers Arena · Vancouver, British Columbia |
| 25 | Sat Dec 2 | vsCapitals | W4-1 | 16-5-4 | 36 PTS | T-Mobile Arena · Las Vegas, NV |
| 26 | Mon Dec 4 | vsBlues | L1-2 (OT) | 16-5-5 | 37 PTS | T-Mobile Arena · Las Vegas, NV |
| 27 | Wed Dec 6 | atBlues | W6-3 | 17-5-5 | 39 PTS | Enterprise Center · St. Louis, MO |
| 28 | Sat Dec 9 | atStars | W6-1 | 18-5-5 | 41 PTS | American Airlines Center · Dallas, TX |
| 29 | Sun Dec 10 | vsSharks | W5-4 (SO) | 19-5-5 | 43 PTS | T-Mobile Arena · Las Vegas, NV |
| 30 | Tue Dec 12 | vsFlames | W5-4 (OT) | 20-5-5 | 45 PTS | T-Mobile Arena · Las Vegas, NV |
| 31 | Fri Dec 15 | vsSabres | L2-5 | 20-6-5 | 45 PTS | T-Mobile Arena · Las Vegas, NV |
| 32 | Sun Dec 17 | vsSenators | W6-3 | 21-6-5 | 47 PTS | T-Mobile Arena · Las Vegas, NV |
| 33 | Tue Dec 19 | atHurricanes | L3-6 | 21-7-5 | 47 PTS | PNC Arena · Raleigh, NC |
| 34 | Thu Dec 21 | atLightning | L4-5 | 21-8-5 | 47 PTS | AMALIE Arena · Tampa, FL |
| 35 | Sat Dec 23 | atPanthers | L2-4 | 21-9-5 | 47 PTS | Amerant Bank Arena · Sunrise, FL |
| 36 | Wed Dec 27 | atDucks | L2-5 | 21-10-5 | 47 PTS | Honda Center · Anaheim, CA |
| 37 | Thu Dec 28 | vsKings | W3-2 | 22-10-5 | 49 PTS | T-Mobile Arena · Las Vegas, NV |
| 38 | Mon Jan 1 | atKraken | L0-3 | 22-11-5 | 49 PTS | Climate Pledge Arena · Seattle, WA |
| 39 | Thu Jan 4 | vsPanthers | L1-4 | 22-12-5 | 49 PTS | T-Mobile Arena · Las Vegas, NV |
| 40 | Sat Jan 6 | vsIslanders | W5-2 | 23-12-5 | 51 PTS | T-Mobile Arena · Las Vegas, NV |
| 41 | Wed Jan 10 | atAvalanche | L0-3 | 23-13-5 | 51 PTS | Ball Arena · Denver, CO |
| 42 | Thu Jan 11 | vsBruins | W2-1 (OT) | 24-13-5 | 53 PTS | T-Mobile Arena · Las Vegas, NV |
| 43 | Sat Jan 13 | vsFlames | L1-3 | 24-14-5 | 53 PTS | T-Mobile Arena · Las Vegas, NV |
| 44 | Mon Jan 15 | vsPredators | W4-1 | 25-14-5 | 55 PTS | T-Mobile Arena · Las Vegas, NV |
| 45 | Thu Jan 18 | vsRangers | W5-1 | 26-14-5 | 57 PTS | T-Mobile Arena · Las Vegas, NV |
| 46 | Sat Jan 20 | vsPenguins | W3-2 | 27-14-5 | 59 PTS | T-Mobile Arena · Las Vegas, NV |
| 47 | Mon Jan 22 | atDevils | L5-6 (OT) | 27-14-6 | 60 PTS | Prudential Center · Newark, NJ |
| 48 | Tue Jan 23 | atIslanders | W3-2 | 28-14-6 | 62 PTS | UBS Arena · Elmont, NY |
| 49 | Fri Jan 26 | atRangers | W5-2 | 29-14-6 | 64 PTS | Madison Square Garden · Manhattan, NY |
| 50 | Sat Jan 27 | atRed Wings | L2-5 | 29-15-6 | 64 PTS | Little Caesars Arena · Detroit, MI |
| 51 | Tue Feb 6 | vsOilers | W3-1 | 30-15-6 | 66 PTS | T-Mobile Arena · Las Vegas, NV |
| 52 | Thu Feb 8 | atCoyotes | W3-2 | 31-15-6 | 68 PTS | Mullett Arena · Tempe, AZ |
| 53 | Mon Feb 12 | vsWild | L3-5 | 31-16-6 | 68 PTS | T-Mobile Arena · Las Vegas, NV |
| 54 | Sat Feb 17 | vsHurricanes | L1-3 | 31-17-6 | 68 PTS | T-Mobile Arena · Las Vegas, NV |
| 55 | Mon Feb 19 | atSharks | W4-0 | 32-17-6 | 70 PTS | SAP Center · San Jose, CA |
| 56 | Tue Feb 20 | vsPredators | L3-5 | 32-18-6 | 70 PTS | T-Mobile Arena · Las Vegas, NV |
| 57 | Thu Feb 22 | vsMaple Leafs | L3-7 | 32-19-6 | 70 PTS | T-Mobile Arena · Las Vegas, NV |
| 58 | Sat Feb 24 | atSenators | L3-4 (SO) | 32-19-7 | 71 PTS | Canadian Tire Centre · Ottawa, ON |
| 59 | Tue Feb 27 | atMaple Leafs | W6-2 | 33-19-7 | 73 PTS | Scotiabank Arena · Toronto, ON |
| 60 | Thu Feb 29 | atBruins | L4-5 | 33-20-7 | 73 PTS | TD Garden · Boston, MA |
| 61 | Sat Mar 2 | atSabres | L2-7 | 33-21-7 | 73 PTS | KeyBank Center · Buffalo, NY |
| 62 | Mon Mar 4 | atJackets | L3-6 | 33-22-7 | 73 PTS | Nationwide Arena · Columbus, OH |
| 63 | Thu Mar 7 | vsCanucks | L1-3 | 33-23-7 | 73 PTS | T-Mobile Arena · Las Vegas, NV |
| 64 | Sat Mar 9 | vsRed Wings | W5-3 | 34-23-7 | 75 PTS | T-Mobile Arena · Las Vegas, NV |
| 65 | Tue Mar 12 | atKraken | W5-4 (OT) | 35-23-7 | 77 PTS | Climate Pledge Arena · Seattle, WA |
| 66 | Thu Mar 14 | atFlames | L1-4 | 35-24-7 | 77 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 67 | Sun Mar 17 | vsDevils | W3-1 | 36-24-7 | 79 PTS | T-Mobile Arena · Las Vegas, NV |
| 68 | Tue Mar 19 | vsLightning | L3-5 | 36-25-7 | 79 PTS | T-Mobile Arena · Las Vegas, NV |
| 69 | Thu Mar 21 | vsKraken | W3-1 | 37-25-7 | 81 PTS | T-Mobile Arena · Las Vegas, NV |
| 70 | Sat Mar 23 | vsJackets | W4-2 | 38-25-7 | 83 PTS | T-Mobile Arena · Las Vegas, NV |
| 71 | Mon Mar 25 | atBlues | W2-1 (OT) | 39-25-7 | 85 PTS | Enterprise Center · St. Louis, MO |
| 72 | Tue Mar 26 | atPredators | L4-5 (OT) | 39-25-8 | 86 PTS | Bridgestone Arena · Nashville, TN |
| 73 | Thu Mar 28 | atJets | W4-1 | 40-25-8 | 88 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 74 | Sat Mar 30 | atWild | W2-1 (OT) | 41-25-8 | 90 PTS | Xcel Energy Center · St. Paul, MN |
| 75 | Tue Apr 2 | vsCanucks | W6-3 | 42-25-8 | 92 PTS | T-Mobile Arena · Las Vegas, NV |
| 76 | Fri Apr 5 | atCoyotes | L4-7 | 42-26-8 | 92 PTS | Mullett Arena · Tempe, AZ |
| 77 | Mon Apr 8 | atCanucks | L3-4 | 42-27-8 | 92 PTS | Rogers Arena · Vancouver, British Columbia |
| 78 | Wed Apr 10 | atOilers | L1-5 | 42-28-8 | 92 PTS | Rogers Place · Edmonton, AB |
| 79 | Fri Apr 12 | vsWild | W7-2 | 43-28-8 | 94 PTS | T-Mobile Arena · Las Vegas, NV |
| 80 | Sun Apr 14 | vsAvalanche | W4-3 (OT) | 44-28-8 | 96 PTS | T-Mobile Arena · Las Vegas, NV |
| 81 | Tue Apr 16 | vsBlackhawks | W3-1 | 45-28-8 | 98 PTS | T-Mobile Arena · Las Vegas, NV |
| 82 | Thu Apr 18 | vsDucks | L1-4 | 45-29-8 | 98 PTS | T-Mobile Arena · Las Vegas, NV |
| 1 | Mon Apr 22 | atStars | W4-3 | 1-0 | 1.000 | American Airlines Center · Dallas, TX |
| 2 | Wed Apr 24 | atStars | W3-1 | 2-0 | 1.000 | American Airlines Center · Dallas, TX |
| 3 | Sat Apr 27 | vsStars | L2-3 (OT) | 2-1 | .667 | T-Mobile Arena · Las Vegas, NV |
| 4 | Mon Apr 29 | vsStars | L2-4 | 2-2 | .500 | T-Mobile Arena · Las Vegas, NV |
| 5 | Wed May 1 | atStars | L2-3 | 2-3 | .400 | American Airlines Center · Dallas, TX |
| 6 | Fri May 3 | vsStars | W2-0 | 3-3 | .500 | T-Mobile Arena · Las Vegas, NV |
| 7 | Sun May 5 | atStars | L1-2 | 3-4 | .429 | American Airlines Center · Dallas, TX |
