| 1 | Mon Nov 4 | vs TBD | W93-52 | 1-0 | 1.000 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 2 | Fri Nov 8 | vsSamford | W88-86 | 2-0 | 1.000 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 3 | Tue Nov 12 | atLa Salle | L77-93 | 2-1 | .667 | - | ESPN+ | Tom Gola Arena · Philadelphia, PA |
| 4 | Sat Nov 16 | vsLafayette | W81-71 | 3-1 | .750 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 5 | Thu Nov 21 | vsRobert Morris | L76-86 | 3-2 | .600 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 6 | Mon Nov 25 | atIona | W84-68 | 4-2 | .667 | - | ESPN+ | Hynes Athletics Center · New Rochelle, NY |
| 7 | Wed Nov 27 | atSyracuse | L72-82 | 4-3 | .571 | - | ESPN+ | JMA Wireless Dome · Syracuse, NY |
| 8 | Wed Dec 4 | atColgate | W84-57 | 5-3 | .625 | - | ESPN+ | Cotterell Court · Hamilton, NY |
| 9 | Sun Dec 8 | atArmy | W103-84 | 6-3 | .667 | - | ESPN+ | Christl Arena · West Point, NY |
| 10 | Tue Dec 10 | atCalifornia | W88-80 | 7-3 | .700 | - | ESPN+ | Haas Pavilion · Berkeley, CA |
| 11 | Sun Dec 22 | vsIllinois St | L77-80 | 7-4 | .636 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 12 | Mon Dec 30 | vsSiena | L77-83 | 7-5 | .583 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 13 | Sun Jan 5 | vsTBD | W123-71 | 8-5 | .615 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 14 | Sat Jan 11 | atColumbia | W94-83 | 9-5 | .643 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 15 | Sat Jan 18 | atPenn | W86-76 | 10-5 | .667 | - | ESPN+ | The Palestra · Philadelphia, PA |
| 16 | Mon Jan 20 | vsBrown | L82-83 | 10-6 | .625 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 17 | Sat Jan 25 | atPrinceton | W85-76 | 11-6 | .647 | - | ESPN+ | Jadwin Gymnasium · Princeton, NJ |
| 18 | Fri Jan 31 | vsDartmouth | W76-64 | 12-6 | .667 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 19 | Sat Feb 1 | vsHarvard | W75-60 | 13-6 | .684 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 20 | Sat Feb 8 | vsYale | L88-103 | 13-7 | .650 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 21 | Fri Feb 14 | atHarvard | L73-75 | 13-8 | .619 | - | ESPN+ | Lavietes Pavilion · Cambridge, MA |
| 22 | Sat Feb 15 | atDartmouth | L49-88 | 13-9 | .591 | - | ESPN+ | Edward Leede Arena · Hanover, NH |
| 23 | Fri Feb 21 | atYale | L88-92 | 13-10 | .565 | - | ESPN+ | John J. Lee Amphitheater · New Haven, CT |
| 24 | Sat Feb 22 | atBrown | W85-81 | 14-10 | .583 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 25 | Fri Feb 28 | vsPenn | W90-62 | 15-10 | .600 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 26 | Sun Mar 2 | vsPrinceton | W102-70 | 16-10 | .615 | - | ESPNU | Newman Arena · Ithaca, NY |
| 27 | Sat Mar 8 | vsColumbia | W100-81 | 17-10 | .630 | - | ESPN+ | Newman Arena · Ithaca, NY |
| 28 | Sat Mar 15 | vsDartmouth | W87-71 | 18-10 | .643 | - | ESPNEWS | Pizzitola Sports Center · Providence, RI |
| 29 | Sun Mar 16 | atYale | L84-90 | 18-11 | .621 | - | ESPN2 | Pizzitola Sports Center · Providence, RI |
