| 1 | Tue Nov 9 | at Binghamton | W76-69 | 1-0 | 1.000 | - | | Events Center (Binghamton) · Binghamton, NY |
| 2 | Fri Nov 12 | atLafayette | W90-85 | 2-0 | 1.000 | - | | Kirby Sports Center · Easton, PA |
| 3 | Tue Nov 16 | vsColgate | W78-68 | 3-0 | 1.000 | - | | Newman Arena · Ithaca, NY |
| 4 | Fri Nov 19 | vsTBD | W107-48 | 4-0 | 1.000 | - | | Newman Arena · Ithaca, NY |
| 5 | Mon Nov 22 | atPenn State | L74-85 | 4-1 | .800 | - | BTN | Bryce Jordan Center · University Park, PA |
| 6 | Wed Nov 24 | vsSt Francis PA | W93-80 | 5-1 | .833 | - | | Newman Arena · Ithaca, NY |
| 7 | Mon Nov 29 | atCanisius | W89-75 | 6-1 | .857 | - | | Koessler Athletic Center · Buffalo, NY |
| 8 | Fri Dec 3 | vsCoppin St | W92-77 | 7-1 | .875 | - | | Newman Arena · Ithaca, NY |
| 9 | Sun Dec 5 | vsTBD | W122-64 | 8-1 | .889 | - | | Newman Arena · Ithaca, NY |
| 10 | Wed Dec 8 | atVirginia Tech | L60-93 | 8-2 | .800 | - | ACC Network | Cassell Coliseum · Blacksburg, VA |
| 12 | Tue Dec 21 | atSyracuse | PPD | 15-11 | .577 | - | | JMA Wireless Dome · Syracuse, NY |
| 14 | Wed Dec 29 | atSyracuse | L68-80 | 8-3 | .727 | - | | JMA Wireless Dome · Syracuse, NY |
| 15 | Sun Jan 2 | vsDartmouth | W79-71 | 9-3 | .750 | - | | Newman Arena · Ithaca, NY |
| 16 | Fri Jan 7 | atPenn | L65-79 | 9-4 | .692 | - | | The Palestra · Philadelphia, PA |
| 17 | Sat Jan 8 | atPrinceton | L70-72 | 9-5 | .643 | - | | Jadwin Gymnasium · Princeton, NJ |
| 18 | Sat Jan 15 | atYale | L69-96 | 9-6 | .600 | - | | John J. Lee Amphitheater · New Haven, CT |
| 19 | Mon Jan 17 | vsColumbia | PPD | 15-11 | .577 | - | | Newman Arena · Ithaca, NY |
| 20 | Sat Jan 22 | vsHarvard | W76-61 | 10-6 | .625 | - | | Newman Arena · Ithaca, NY |
| 21 | Sun Jan 30 | atBrown | W74-72 | 11-6 | .647 | - | | Pizzitola Sports Center · Providence, RI |
| 22 | Fri Feb 4 | vsPrinceton | W88-83 | 12-6 | .667 | - | | Newman Arena · Ithaca, NY |
| 23 | Sat Feb 5 | vsPenn | L68-73 | 12-7 | .632 | - | | Newman Arena · Ithaca, NY |
| 24 | Wed Feb 9 | vsColumbia | W88-75 | 13-7 | .650 | - | | Newman Arena · Ithaca, NY |
| 25 | Sat Feb 12 | vsBrown | L80-81 | 13-8 | .619 | - | | Newman Arena · Ithaca, NY |
| 26 | Fri Feb 18 | atDartmouth | L59-71 | 13-9 | .591 | - | | Edward Leede Arena · Hanover, NH |
| 27 | Sat Feb 19 | atHarvard | L72-77 (OT) | 13-10 | .565 | - | | Lavietes Pavilion · Cambridge, MA |
| 28 | Sat Feb 26 | vsYale | W71-65 | 14-10 | .583 | - | | Newman Arena · Ithaca, NY |
| 29 | Sat Mar 5 | atColumbia | W78-64 | 15-10 | .600 | - | | Francis S. Levien Gymnasium · New York, NY |
| 30 | Sat Mar 12 | atPrinceton | L73-77 | 15-11 | .577 | - | ESPNU | Jadwin Gymnasium · Princeton, NJ |
