| 1 | Mon Nov 7 | at Boston College | L77-79 | 0-1 | .000 | - | | Silvio O. Conte Forum · Chestnut Hill, MA |
| 2 | Thu Nov 10 | vsTBD | W114-57 | 1-1 | .500 | - | | Newman Arena · Ithaca, NY |
| 3 | Mon Nov 14 | atSt Francis PA | W80-77 | 2-1 | .667 | - | | DeGol Arena · Loretto, PA |
| 4 | Fri Nov 18 | vsTBD | W83-61 | 3-1 | .750 | - | | Newman Arena · Ithaca, NY |
| 5 | Tue Nov 22 | vsCanisius | W79-70 | 4-1 | .800 | - | | Newman Arena · Ithaca, NY |
| 6 | Fri Nov 25 | atMonmouth | W81-63 | 5-1 | .833 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 7 | Thu Dec 1 | atDelaware | W74-67 | 6-1 | .857 | - | | Bob Carpenter Center · Newark, DE |
| 8 | Sun Dec 4 | vsLafayette | W73-68 | 7-1 | .875 | - | | Newman Arena · Ithaca, NY |
| 9 | Wed Dec 7 | atMiami | L105-107 | 7-2 | .778 | - | | Watsco Center · Coral Gables, FL |
| 10 | Sat Dec 17 | atSyracuse | L63-78 | 7-3 | .700 | - | ACC Network | JMA Wireless Dome · Syracuse, NY |
| 11 | Tue Dec 20 | vsLehigh | W96-64 | 8-3 | .727 | - | | Newman Arena · Ithaca, NY |
| 12 | Thu Dec 22 | atColgate | W91-80 | 9-3 | .750 | - | | Cotterell Court · Hamilton, NY |
| 13 | Thu Dec 29 | vsBinghamton | W86-70 | 10-3 | .769 | - | | Newman Arena · Ithaca, NY |
| 14 | Sun Jan 1 | atDartmouth | W74-63 | 11-3 | .786 | - | | Edward Leede Arena · Hanover, NH |
| 15 | Fri Jan 6 | vsPenn | W88-69 | 12-3 | .800 | - | | Newman Arena · Ithaca, NY |
| 16 | Sat Jan 7 | vsPrinceton | L68-75 | 12-4 | .750 | - | | Newman Arena · Ithaca, NY |
| 17 | Fri Jan 13 | vsYale | W94-82 | 13-4 | .765 | - | ESPNU | Newman Arena · Ithaca, NY |
| 18 | Mon Jan 16 | atColumbia | W102-85 | 14-4 | .778 | - | | Francis S. Levien Gymnasium · New York, NY |
| 19 | Sat Jan 21 | atHarvard | L89-95 | 14-5 | .737 | - | | Lavietes Pavilion · Cambridge, MA |
| 20 | Sat Jan 28 | vsBrown | W80-73 | 15-5 | .750 | - | | Newman Arena · Ithaca, NY |
| 21 | Fri Feb 3 | atPrinceton | L82-89 | 15-6 | .714 | - | | Jadwin Gymnasium · Princeton, NJ |
| 22 | Sat Feb 4 | atPenn | L86-92 | 15-7 | .682 | - | | The Palestra · Philadelphia, PA |
| 23 | Sat Feb 11 | atBrown | L66-80 | 15-8 | .652 | - | | Pizzitola Sports Center · Providence, RI |
| 24 | Fri Feb 17 | vsDartmouth | W95-83 (OT) | 16-8 | .667 | - | | Newman Arena · Ithaca, NY |
| 25 | Sat Feb 18 | vsHarvard | L56-73 | 16-9 | .640 | - | | Newman Arena · Ithaca, NY |
| 26 | Sat Feb 25 | atYale | L58-76 | 16-10 | .615 | - | | John J. Lee Amphitheater · New Haven, CT |
| 27 | Sat Mar 4 | vsColumbia | W87-73 | 17-10 | .630 | - | | Newman Arena · Ithaca, NY |
| 28 | Sat Mar 11 | atYale | L60-80 | 17-11 | .607 | - | ESPNU | Jadwin Gymnasium · Princeton, NJ |
