| 1 | Mon Nov 3 | at Providence | L79-89 | 0-1 | .000 | - | ESPN+ | Amica Mutual Pavilion · Providence, RI |
| 2 | Sat Nov 8 | at8BYU | L53-98 | 0-2 | .000 | - | ESPN+ | Marriott Center · Provo, UT |
| 3 | Mon Nov 10 | atUtah | L69-87 | 0-3 | .000 | - | ESPN+ | Jon M. Huntsman Center · Salt Lake City, UT |
| 4 | Sun Nov 16 | atHampton | W67-61 | 1-3 | .250 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 5 | Tue Nov 18 | atBrown | L49-68 | 1-4 | .200 | - | ESPN+ | Pizzitola Sports Center · Providence, RI |
| 6 | Fri Nov 21 | atSacred Heart | L66-79 | 1-5 | .167 | - | ESPN+ | William H. Pitt Center · Fairfield, CT |
| 7 | Mon Nov 24 | vsSiena | L69-73 | 1-6 | .143 | - | ESPN+ | Hart Center · Worcester, MA |
| 8 | Wed Nov 26 | vsTBD | W77-53 | 2-6 | .250 | - | ESPN+ | Hart Center · Worcester, MA |
| 9 | Wed Dec 3 | vsNortheastern | W76-59 | 3-6 | .333 | - | ESPN+ | Hart Center · Worcester, MA |
| 10 | Sat Dec 6 | atFordham | W70-69 | 4-6 | .400 | - | ESPN+ | Rose Hill Gymnasium · Bronx, NY |
| 11 | Tue Dec 9 | vsTBD | W69-47 | 5-6 | .455 | - | ESPN+ | Hart Center · Worcester, MA |
| 12 | Tue Dec 16 | vsDartmouth | L64-89 | 5-7 | .417 | - | ESPN+ | Hart Center · Worcester, MA |
| 13 | Sat Dec 20 | atHarvard | L53-81 | 5-8 | .385 | - | ESPN+ | Lavietes Pavilion · Cambridge, MA |
| 14 | Wed Dec 31 | vsBucknell | W65-58 | 6-8 | .429 | - | ESPN+ | Hart Center · Worcester, MA |
| 15 | Sat Jan 3 | vsNavy | L58-65 | 6-9 | .400 | - | ESPN+ | Hart Center · Worcester, MA |
| 16 | Wed Jan 7 | atLehigh | L58-66 | 6-10 | .375 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
| 17 | Sat Jan 10 | atAmerican | W84-73 | 7-10 | .412 | - | ESPN+ | Bender Arena · Washington, D.C. |
| 18 | Wed Jan 14 | vsArmy | W82-75 | 8-10 | .444 | - | ESPN+ | Hart Center · Worcester, MA |
| 19 | Sat Jan 17 | atLafayette | L55-74 | 8-11 | .421 | - | ESPN+ | Kirby Sports Center · Easton, PA |
| 20 | Wed Jan 21 | atNavy | L68-85 | 8-12 | .400 | - | ESPN+ | Alumni Hall (Navy) · Annapolis, MD |
| 21 | Sat Jan 24 | vsAmerican | L67-76 | 8-13 | .381 | - | ESPN+ | Hart Center · Worcester, MA |
| 22 | Wed Jan 28 | atColgate | L74-79 | 8-14 | .364 | - | ESPN+ | Cotterell Court · Hamilton, NY |
| 23 | Sat Jan 31 | atArmy | L68-69 | 8-15 | .348 | - | ESPN+ | Christl Arena · West Point, NY |
| 24 | Mon Feb 2 | vsBoston Univ | L64-72 | 8-16 | .333 | - | CBSSN | Hart Center · Worcester, MA |
| 25 | Sat Feb 7 | vsLehigh | W76-67 | 9-16 | .360 | - | ESPN+ | Hart Center · Worcester, MA |
| 26 | Wed Feb 11 | vsColgate | L70-74 | 9-17 | .346 | - | ESPN+ | Hart Center · Worcester, MA |
| 27 | Sun Feb 15 | atLoyola MD | L73-83 | 9-18 | .333 | - | ESPN+ | Reitz Arena · Baltimore, MD |
| 28 | Wed Feb 18 | vsLafayette | L83-86 | 9-19 | .321 | - | ESPN+ | Hart Center · Worcester, MA |
| 29 | Sun Feb 22 | atBucknell | W72-63 | 10-19 | .345 | - | ESPN+ | Sojka Pavilion · Lewisburg, PA |
| 30 | Wed Feb 25 | atBoston Univ | L63-78 | 10-20 | .333 | - | ESPN+ | Case Gym · Boston, MA |
| 31 | Sat Feb 28 | vsLoyola MD | L62-76 | 10-21 | .323 | - | ESPN+ | Hart Center · Worcester, MA |
| 32 | Tue Mar 3 | atLafayette | W82-77 | 11-21 | .344 | - | ESPN+ | Kirby Sports Center · Easton, PA |
| 33 | Thu Mar 5 | atLehigh | L66-69 | 11-22 | .333 | - | ESPN+ | Stabler Arena · Bethlehem, PA |
