| 1 | Tue Nov 9 | vs TBD | W87-59 | 1-0 | 1.000 | - | | Burr Gymnasium · Washington, D.C. |
| 2 | Wed Nov 10 | vsTBD | W118-54 | 2-0 | 1.000 | - | | Burr Gymnasium · Washington, D.C. |
| 3 | Sat Nov 13 | at Bradley | W76-64 | 3-0 | 1.000 | - | | Carver Arena · Peoria, IL |
| 4 | Tue Nov 16 | at #5Villanova | L81-100 | 3-1 | .750 | - | FS2 | Finneran Pavilion · Villanova, PA |
| 5 | Sat Nov 20 | at High Point | L63-73 | 3-2 | .600 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 6 | Sun Nov 21 | at William & Mary | W82-76 | 4-2 | .667 | - | | Kaplan Arena · Williamsburg, VA |
| 7 | Fri Nov 26 | vs Austin Peay | L67-69 | 4-3 | .571 | - | | Burr Gymnasium · Washington, D.C. |
| 8 | Tue Nov 30 | at Mount St Mary | L70-72 | 4-4 | .500 | - | | Knott Arena · Emmitsburg, MD |
| 9 | Sat Dec 4 | vs American | W90-56 | 5-4 | .556 | - | | Burr Gymnasium · Washington, D.C. |
| 10 | Wed Dec 15 | at Georgetown | L73-85 | 5-5 | .500 | - | FS1 | Capital One Arena · Washington, D.C. |
| 11 | Sat Dec 18 | vs NC A&T | W79-57 | 6-5 | .545 | - | TNT | Burr Gymnasium · Washington, D.C. |
| 12 | Tue Dec 21 | at Harvard | L69-77 | 6-6 | .500 | - | | Lavietes Pavilion · Cambridge, MA |
| 16 | Sat Jan 8 | at Delaware St | PPD | 16-13 | .552 | - | | Memorial Hall (Dover, DE) · Dover, DE |
| 17 | Mon Jan 10 | vs MD-Eastern | PPD | 16-13 | .552 | - | | Burr Gymnasium · Washington, D.C. |
| 18 | Sat Jan 15 | vs Norfolk St | L74-77 | 6-7 | .462 | - | | Burr Gymnasium · Washington, D.C. |
| 19 | Mon Jan 17 | vs Notre Dame | L68-71 | 6-8 | .429 | - | FOX | Burr Gymnasium · Washington, D.C. |
| 20 | Sat Jan 22 | at Morgan St | W91-82 | 7-8 | .467 | - | | Hill Field House · Baltimore, MD |
| 21 | Mon Jan 24 | at Coppin St | L81-83 | 7-9 | .438 | - | | Physical Education Complex · Baltimore, MD |
| 22 | Sat Jan 29 | at NC Central | W75-74 (OT) | 8-9 | .471 | - | | McDougald-McLendon Arena · Durham, NC |
| 23 | Mon Jan 31 | at SC State | L55-58 | 8-10 | .444 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 24 | Sat Feb 5 | vsMD-Eastern | W72-64 | 9-10 | .474 | - | | Burr Gymnasium · Washington, D.C. |
| 25 | Mon Feb 7 | atDelaware St | W69-64 | 10-10 | .500 | - | | Memorial Hall (Dover, DE) · Dover, DE |
| 26 | Tue Feb 8 | vsTBD | W96-38 | 11-10 | .524 | - | | Burr Gymnasium · Washington, D.C. |
| 27 | Sat Feb 12 | vsDelaware St | W85-72 | 12-10 | .545 | - | | Burr Gymnasium · Washington, D.C. |
| 28 | Mon Feb 14 | atMD-Eastern | W77-71 | 13-10 | .565 | - | | Hytche Athletic Center · Princess Anne, MD |
| 29 | Sat Feb 19 | vsMorgan St | W68-66 | 14-10 | .583 | - | ESPN2 | Burr Gymnasium · Washington, D.C. |
| 30 | Mon Feb 21 | vsCoppin St | L82-86 | 14-11 | .560 | - | ESPNU | Burr Gymnasium · Washington, D.C. |
| 31 | Sat Feb 26 | vsNC Central | W77-67 | 15-11 | .577 | - | | Burr Gymnasium · Washington, D.C. |
| 32 | Mon Feb 28 | vsSC State | W72-62 | 16-11 | .593 | - | | Burr Gymnasium · Washington, D.C. |
| 33 | Thu Mar 3 | atNorfolk St | L61-83 | 16-12 | .571 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 34 | Wed Mar 9 | vsCoppin St | L57-59 | 16-13 | .552 | - | | Burr Gymnasium · Washington, D.C. |
