| 1 | Mon Nov 7 | vs TBD | W105-49 | 1-0 | 1.000 | - | | McLeod Center · Cedar Falls, IA |
| 2 | Fri Nov 11 | at Richmond | L55-68 | 1-1 | .500 | - | | Robins Center · Richmond, VA |
| 4 | Mon Nov 21 | at San Francisco | L69-75 | 1-2 | .333 | - | CBS | War Memorial at the Sobrato Center · San Francisco, CA |
| 5 | Tue Nov 22 | at Grand Canyon | L67-69 | 1-3 | .250 | - | CBS | GCU Arena · Phoenix, AZ |
| 6 | Sat Nov 26 | vs N Illinois | W83-76 | 2-3 | .400 | - | | McLeod Center · Cedar Falls, IA |
| 7 | Wed Nov 30 | at Bradley | L53-68 | 2-4 | .333 | - | | Carver Arena · Peoria, IL |
| 8 | Sat Dec 3 | vs Evansville | W72-55 | 3-4 | .429 | - | | McLeod Center · Cedar Falls, IA |
| 9 | Tue Dec 6 | vs Toledo | L75-83 | 3-5 | .375 | - | | McLeod Center · Cedar Falls, IA |
| 10 | Fri Dec 9 | vs McNeese | L49-52 | 3-6 | .333 | - | | McLeod Center · Cedar Falls, IA |
| 11 | Mon Dec 12 | vs South Florida | L69-72 | 3-7 | .300 | - | | McLeod Center · Cedar Falls, IA |
| 12 | Sat Dec 17 | vs Towson | W83-66 | 4-7 | .364 | - | | McLeod Center · Cedar Falls, IA |
| 13 | Wed Dec 21 | vs St Bonaventure | W62-52 | 5-7 | .417 | - | | McLeod Center · Cedar Falls, IA |
| 14 | Wed Dec 28 | vs Missouri St | L67-79 | 5-8 | .385 | - | | McLeod Center · Cedar Falls, IA |
| 15 | Sat Dec 31 | at Illinois St | W66-60 | 6-8 | .429 | - | | Redbird Arena · Normal, IL |
| 16 | Wed Jan 4 | at Valparaiso | W69-67 | 7-8 | .467 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 17 | Sat Jan 7 | vs S Illinois | W69-57 | 8-8 | .500 | - | | McLeod Center · Cedar Falls, IA |
| 18 | Tue Jan 10 | vs Murray St | W75-67 | 9-8 | .529 | - | | McLeod Center · Cedar Falls, IA |
| 19 | Sat Jan 14 | at Belmont | L72-76 | 9-9 | .500 | - | | Curb Event Center Arena · Nashville, TN |
| 20 | Wed Jan 18 | vsIllinois St | W65-63 | 10-9 | .526 | - | | McLeod Center · Cedar Falls, IA |
| 21 | Sat Jan 21 | at UIC | W78-72 | 11-9 | .550 | - | | Credit Union 1 Arena · Chicago, IL |
| 22 | Wed Jan 25 | vsValparaiso | W77-66 | 12-9 | .571 | - | | McLeod Center · Cedar Falls, IA |
| 23 | Sat Jan 28 | at Indiana St | L71-79 | 12-10 | .545 | - | | Hulman Center · Terre Haute, IN |
| 24 | Wed Feb 1 | at Drake | L81-88 (2OT) | 12-11 | .522 | - | | The Knapp Center · Des Moines, IA |
| 25 | Sat Feb 4 | vsBradley | L69-77 | 12-12 | .500 | - | ESPNEWS | McLeod Center · Cedar Falls, IA |
| 26 | Wed Feb 8 | atEvansville | L59-71 | 12-13 | .480 | - | | Ford Center · Evansville, IN |
| 27 | Sat Feb 11 | vsIndiana St | L62-80 | 12-14 | .462 | - | | McLeod Center · Cedar Falls, IA |
| 28 | Wed Feb 15 | vsDrake | L74-82 | 12-15 | .444 | - | | McLeod Center · Cedar Falls, IA |
| 29 | Sat Feb 18 | atMissouri St | W69-66 | 13-15 | .464 | - | | Great Southern Bank Arena · Springfield, MO |
| 30 | Wed Feb 22 | atS Illinois | L63-86 | 13-16 | .448 | - | | Banterra Center · Carbondale, IL |
| 31 | Sun Feb 26 | vsBelmont | L75-83 | 13-17 | .433 | - | CBS | McLeod Center · Cedar Falls, IA |
| 32 | Thu Mar 2 | vsIllinois St | W75-62 | 14-17 | .452 | - | | McLeod Center · Cedar Falls, IA |
| 33 | Fri Mar 3 | atBradley | L66-72 | 14-18 | .438 | - | | Carver Arena · Peoria, IL |
#16Virginia