| 1 | Wed Nov 25 | at Virginia Tech | L62-77 | 0-1 | .000 | - | | Cassell Coliseum · Blacksburg, VA |
| 2 | Sat Nov 28 | at Norfolk St | L54-57 | 0-2 | .000 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 3 | Sun Nov 29 | at JMU | L59-67 | 0-3 | .000 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 5 | Sat Dec 5 | at E Carolina | L50-63 | 0-4 | .000 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 6 | Wed Dec 9 | vs TBD | W98-50 | 1-4 | .200 | - | | Donald N. Dedmon Center · Radford, VA |
| 7 | Mon Dec 14 | vs Longwood | W67-66 | 2-4 | .333 | - | | Donald N. Dedmon Center · Radford, VA |
| 8 | Tue Dec 15 | vsLongwood | W62-53 | 3-4 | .429 | - | | Donald N. Dedmon Center · Radford, VA |
| 9 | Sat Dec 19 | at Vanderbilt | L50-59 | 3-5 | .375 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 10 | Wed Dec 30 | at Presbyterian | W71-65 | 4-5 | .444 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 11 | Thu Dec 31 | atPresbyterian | L63-65 | 4-6 | .400 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 12 | Mon Jan 4 | vs Hampton | W79-66 | 5-6 | .455 | - | ESPNU | Donald N. Dedmon Center · Radford, VA |
| 13 | Tue Jan 5 | vsHampton | W76-65 | 6-6 | .500 | - | | Donald N. Dedmon Center · Radford, VA |
| 14 | Sat Jan 9 | at Charleston So | W79-64 | 7-6 | .538 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 15 | Sun Jan 10 | atCharleston So | W68-48 | 8-6 | .571 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 16 | Thu Jan 14 | vs Gardner-Webb | PPD | 15-12 | .556 | - | | Donald N. Dedmon Center · Radford, VA |
| 17 | Fri Jan 15 | vsGardner-Webb | PPD | 15-12 | .556 | - | | Donald N. Dedmon Center · Radford, VA |
| 18 | Tue Jan 19 | at Campbell | W97-91 (3OT) | 9-6 | .600 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 19 | Wed Jan 20 | atCampbell | W67-61 | 10-6 | .625 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 20 | Sun Jan 24 | at UNC Asheville | L68-76 (OT) | 10-7 | .588 | - | | Kimmel Arena · Asheville, NC |
| 21 | Mon Jan 25 | atUNC Asheville | W73-63 | 11-7 | .611 | - | | Kimmel Arena · Asheville, NC |
| 22 | Thu Feb 4 | vs SC Upstate | W63-61 | 12-7 | .632 | - | | Donald N. Dedmon Center · Radford, VA |
| 23 | Fri Feb 5 | vsSC Upstate | W102-66 | 13-7 | .650 | - | | Donald N. Dedmon Center · Radford, VA |
| 24 | Thu Feb 11 | vs Winthrop | L64-80 | 13-8 | .619 | - | | Donald N. Dedmon Center · Radford, VA |
| 25 | Fri Feb 12 | vsWinthrop | L47-55 | 13-9 | .591 | - | | Donald N. Dedmon Center · Radford, VA |
| 26 | Wed Feb 17 | vsGardner-Webb | L57-69 | 13-10 | .565 | - | | Donald N. Dedmon Center · Radford, VA |
| 27 | Thu Feb 18 | vsGardner-Webb | L49-77 | 13-11 | .542 | - | | Donald N. Dedmon Center · Radford, VA |
| 28 | Wed Feb 24 | vsTBD | W74-51 | 14-11 | .560 | - | | Donald N. Dedmon Center · Radford, VA |
| 29 | Mon Mar 1 | vsHampton | W67-52 | 15-11 | .577 | - | | Donald N. Dedmon Center · Radford, VA |
| 30 | Thu Mar 4 | vsCampbell | L60-78 | 15-12 | .556 | - | | Donald N. Dedmon Center · Radford, VA |
