| 1 | Fri Nov 8 | at Liberty | L60-66 | 0-1 | .000 | - | | Liberty Arena · Lynchburg, VA |
| 2 | Tue Nov 12 | vs TBD | W91-40 | 1-1 | .500 | - | | Donald N. Dedmon Center · Radford, VA |
| 3 | Fri Nov 15 | at Georgia So | L73-76 | 1-2 | .333 | - | | W.S. Hanner Fieldhouse · Statesboro, GA |
| 4 | Tue Nov 19 | at Northwestern | W67-56 | 2-2 | .500 | - | | Welsh-Ryan Arena · Evanston, IL |
| 5 | Fri Nov 22 | at Bradley | L61-70 | 2-3 | .400 | - | | Carver Arena · Peoria, IL |
| 6 | Tue Nov 26 | at Monmouth | L63-80 | 2-4 | .333 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 7 | Wed Dec 4 | vs JMU | W94-71 | 3-4 | .429 | - | | Donald N. Dedmon Center · Radford, VA |
| 8 | Sat Dec 7 | vs UNC Greensboro | L58-60 | 3-5 | .375 | - | | Donald N. Dedmon Center · Radford, VA |
| 9 | Sat Dec 14 | at Duquesne | L49-71 | 3-6 | .333 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 10 | Wed Dec 18 | at Mississippi St | L68-77 | 3-7 | .300 | - | | Humphrey Coliseum · Starkville, MS |
| 11 | Sun Dec 22 | at Richmond | W73-58 | 4-7 | .364 | - | | Robins Center · Richmond, VA |
| 12 | Sun Dec 29 | vsTBD | W90-45 | 5-7 | .417 | - | | Donald N. Dedmon Center · Radford, VA |
| 13 | Sat Jan 4 | vs High Point | W73-62 | 6-7 | .462 | - | | Donald N. Dedmon Center · Radford, VA |
| 14 | Wed Jan 8 | at Gardner-Webb | W67-64 | 7-7 | .500 | - | | Paul Porter Arena · Boiling Springs, NC |
| 15 | Sat Jan 11 | vs Campbell | W68-63 | 8-7 | .533 | - | | Donald N. Dedmon Center · Radford, VA |
| 16 | Thu Jan 16 | at SC Upstate | W63-59 | 9-7 | .563 | - | | G.B. Hodge Center · Spartanburg, SC |
| 17 | Sat Jan 18 | at Presbyterian | W75-64 | 10-7 | .588 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 18 | Mon Jan 20 | vs Winthrop | L56-61 | 10-8 | .556 | - | | Donald N. Dedmon Center · Radford, VA |
| 19 | Thu Jan 23 | at UNC Asheville | L67-80 | 10-9 | .526 | - | | Kimmel Arena · Asheville, NC |
| 20 | Sat Jan 25 | vs Hampton | W83-79 | 11-9 | .550 | - | | Donald N. Dedmon Center · Radford, VA |
| 21 | Thu Jan 30 | at Longwood | W67-55 | 12-9 | .571 | - | | Willett Hall · Farmville, VA |
| 22 | Sat Feb 1 | vs Charleston So | W77-74 (OT) | 13-9 | .591 | - | | Donald N. Dedmon Center · Radford, VA |
| 23 | Sat Feb 8 | atHigh Point | W81-70 | 14-9 | .609 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 24 | Mon Feb 10 | atWinthrop | W81-77 | 15-9 | .625 | - | | Winthrop Coliseum · Rock Hill, SC |
| 25 | Thu Feb 13 | vsPresbyterian | W81-71 | 16-9 | .640 | - | | Donald N. Dedmon Center · Radford, VA |
| 26 | Sat Feb 15 | atCampbell | W73-60 | 17-9 | .654 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 27 | Thu Feb 20 | vsUNC Asheville | W79-64 | 18-9 | .667 | - | ESPNU | Donald N. Dedmon Center · Radford, VA |
| 28 | Sat Feb 22 | vsSC Upstate | W81-60 | 19-9 | .679 | - | | Donald N. Dedmon Center · Radford, VA |
| 29 | Thu Feb 27 | atHampton | W81-78 | 20-9 | .690 | - | ESPNU | Convocation Center (VA) · Hampton, VA |
| 30 | Sat Feb 29 | vsGardner-Webb | L62-70 | 20-10 | .667 | - | | Donald N. Dedmon Center · Radford, VA |
| 31 | Thu Mar 5 | vsCharleston So | W62-48 | 21-10 | .677 | - | | Donald N. Dedmon Center · Radford, VA |
| 32 | Fri Mar 6 | vsHampton | L78-86 | 21-11 | .656 | - | | Donald N. Dedmon Center · Radford, VA |
