| 1 | Mon Nov 3 | vs South Alabama | L74-76 | 0-1 | .000 | - | ESPN+ | Savage Arena · Toledo, OH |
| 2 | Sat Nov 8 | vsMarshall | L73-85 | 0-2 | .000 | - | ESPN+ | Savage Arena · Toledo, OH |
| 3 | Tue Nov 11 | atWright St | W81-71 | 1-2 | .333 | - | ESPN+ | Nutter Center · Dayton, OH |
| 4 | Sat Nov 15 | vsDetroit Mercy | W90-83 | 2-2 | .500 | - | ESPN+ | Savage Arena · Toledo, OH |
| 5 | Wed Nov 19 | vsYoungstown St | W92-75 | 3-2 | .600 | - | ESPN+ | Savage Arena · Toledo, OH |
| 6 | Mon Nov 24 | atTroy | W75-68 | 4-2 | .667 | - | | Alico Arena · Fort Myers, FL |
| 7 | Wed Nov 26 | vsBelmont | L72-87 | 4-3 | .571 | - | | Alico Arena · Fort Myers, FL |
| 8 | Mon Dec 1 | vsTBD | W102-58 | 5-3 | .625 | - | ESPN+ | Savage Arena · Toledo, OH |
| 9 | Sat Dec 6 | atOakland | L97-98 | 5-4 | .556 | - | ESPN+ | Athletics Center O'rena · Rochester, MI |
| 10 | Sat Dec 13 | atRobert Morris | L70-75 | 5-5 | .500 | - | ESPN+ | UPMC Events Center · Moon Township, PA |
| 11 | Tue Dec 16 | at9Michigan St | L69-92 | 5-6 | .455 | - | Peacock | Breslin Center · East Lansing, MI |
| 12 | Sat Dec 20 | vsTBD | W100-67 | 6-6 | .500 | - | ESPN+ | Savage Arena · Toledo, OH |
| 13 | Tue Dec 30 | vsW Michigan | W84-79 | 7-6 | .538 | - | ESPN+ | Savage Arena · Toledo, OH |
| 14 | Sat Jan 3 | atC Michigan | W78-75 | 8-6 | .571 | - | ESPN+ | McGuirk Arena · Mount Pleasant, MI |
| 15 | Tue Jan 6 | atN Illinois | W75-61 | 9-6 | .600 | - | ESPN+ | NIU Convocation Center · Dekalb, IL |
| 16 | Fri Jan 9 | vsMiami OH | L73-87 | 9-7 | .563 | - | CBSSN | Savage Arena · Toledo, OH |
| 17 | Tue Jan 13 | vsOhio | W101-85 | 10-7 | .588 | - | ESPN+ | Savage Arena · Toledo, OH |
| 18 | Fri Jan 16 | atKent State | L84-87 | 10-8 | .556 | - | CBSSN | M.A.C. Center · Kent, OH |
| 19 | Tue Jan 20 | atUMass | L82-84 | 10-9 | .526 | - | ESPN+ | William D. Mullins Memorial Center · Amherst, MA |
| 20 | Sat Jan 24 | vsBowling Green | W73-72 | 11-9 | .550 | - | ESPN+ | Savage Arena · Toledo, OH |
| 21 | Tue Jan 27 | atAkron | L81-91 | 11-10 | .524 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 22 | Sat Jan 31 | vsBall State | W73-55 | 12-10 | .545 | - | ESPN+ | Savage Arena · Toledo, OH |
| 23 | Tue Feb 3 | vsKent State | L72-75 | 12-11 | .522 | - | ESPN+ | Savage Arena · Toledo, OH |
| 24 | Sat Feb 7 | atJMU | L71-73 | 12-12 | .500 | - | ESPN+ | Atlantic Union Bank Center · Harrisonburg, VA |
| 25 | Wed Feb 11 | atW Michigan | W90-79 | 13-12 | .520 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 26 | Sat Feb 14 | atBowling Green | L70-80 | 13-13 | .500 | - | ESPN+ | Stroh Center · Bowling Green, OH |
| 27 | Sat Feb 21 | vsE Michigan | W94-75 | 14-13 | .519 | - | ESPN+ | Savage Arena · Toledo, OH |
| 28 | Tue Feb 24 | vsN Illinois | W79-69 | 15-13 | .536 | - | ESPN+ | Savage Arena · Toledo, OH |
| 29 | Sat Feb 28 | atOhio | W79-67 | 16-13 | .552 | - | ESPN+ | Convocation Center (OH) · Athens, OH |
