| 1 | Wed Dec 9 | vs TBD | W72-52 | 1-0 | 1.000 | - | | Beeghly Center · Youngstown, OH |
| 2 | Sun Dec 13 | at Binghamton | W79-65 | 2-0 | 1.000 | - | | Events Center (Binghamton) · Binghamton, NY |
| 3 | Mon Dec 14 | vsTBD | W80-66 | 3-0 | 1.000 | - | | Beeghly Center · Youngstown, OH |
| 4 | Sat Dec 19 | at N Kentucky | L64-79 | 3-1 | .750 | - | | Truist Arena · Highland Heights, KY |
| 5 | Sun Dec 20 | atN Kentucky | W70-60 | 4-1 | .800 | - | ESPN2 | Truist Arena · Highland Heights, KY |
| 6 | Sat Dec 26 | at Cleveland St | L69-87 | 4-2 | .667 | - | | Wolstein Center · Cleveland, OH |
| 7 | Sun Dec 27 | atCleveland St | L74-81 | 4-3 | .571 | - | | Wolstein Center · Cleveland, OH |
| 8 | Fri Jan 1 | vs Green Bay | W84-77 | 5-3 | .625 | - | | Beeghly Center · Youngstown, OH |
| 9 | Sat Jan 2 | vsGreen Bay | L69-79 | 5-4 | .556 | - | | Beeghly Center · Youngstown, OH |
| 10 | Mon Jan 4 | vsTBD | W109-56 | 6-4 | .600 | - | | Beeghly Center · Youngstown, OH |
| 11 | Fri Jan 8 | at Wright St | W74-72 | 7-4 | .636 | - | ESPN2 | Nutter Center · Dayton, OH |
| 12 | Sat Jan 9 | atWright St | L55-93 | 7-5 | .583 | - | | Nutter Center · Dayton, OH |
| 13 | Fri Jan 15 | at Oakland | L65-82 | 7-6 | .538 | - | | Athletics Center O'rena · Rochester, MI |
| 14 | Sat Jan 16 | atOakland | L74-81 | 7-7 | .500 | - | | Athletics Center O'rena · Rochester, MI |
| 15 | Fri Jan 22 | vs UIC | L66-67 | 7-8 | .467 | - | | Beeghly Center · Youngstown, OH |
| 16 | Sat Jan 23 | vsUIC | W85-77 | 8-8 | .500 | - | | Beeghly Center · Youngstown, OH |
| 17 | Fri Jan 29 | vs Detroit Mercy | L75-78 | 8-9 | .471 | - | | Beeghly Center · Youngstown, OH |
| 18 | Sat Jan 30 | vsDetroit Mercy | L72-77 | 8-10 | .444 | - | | Beeghly Center · Youngstown, OH |
| 19 | Fri Feb 5 | at Robert Morris | W84-78 (OT) | 9-10 | .474 | - | | UPMC Events Center · Moon Township, PA |
| 20 | Sat Feb 6 | atRobert Morris | W70-66 (OT) | 10-10 | .500 | - | | UPMC Events Center · Moon Township, PA |
| 21 | Mon Feb 8 | vsTBD | W60-50 | 11-10 | .524 | - | | Beeghly Center · Youngstown, OH |
| 22 | Fri Feb 12 | vs Purdue FW | W84-70 | 12-10 | .545 | - | | Beeghly Center · Youngstown, OH |
| 23 | Sat Feb 13 | vsPurdue FW | W72-70 | 13-10 | .565 | - | | Beeghly Center · Youngstown, OH |
| 24 | Fri Feb 19 | vs IU Indy | L70-72 | 13-11 | .542 | - | | Beeghly Center · Youngstown, OH |
| 25 | Sat Feb 20 | vsIU Indy | W77-70 | 14-11 | .560 | - | | Beeghly Center · Youngstown, OH |
| 26 | Thu Feb 25 | vsUIC | W74-58 | 15-11 | .577 | - | | Beeghly Center · Youngstown, OH |
| 27 | Tue Mar 2 | atOakland | L83-87 (OT) | 15-12 | .556 | - | | Athletics Center O'rena · Rochester, MI |
