| 1 | Wed Nov 10 | at Penn State | L59-75 | 0-1 | .000 | - | BTN | Bryce Jordan Center · University Park, PA |
| 2 | Sat Nov 13 | at SE Missouri St | W97-79 | 1-1 | .500 | - | | Show Me Center · Cape Girardeau, MO |
| 3 | Fri Nov 19 | vs St Thomas (MN) | W79-75 | 2-1 | .667 | - | | Beeghly Center · Youngstown, OH |
| 4 | Sat Nov 20 | vs SIUE | L66-69 | 2-2 | .500 | - | | Beeghly Center · Youngstown, OH |
| 5 | Sun Nov 21 | vs Niagara | L53-58 | 2-3 | .400 | - | | Beeghly Center · Youngstown, OH |
| 6 | Thu Dec 2 | at Milwaukee | W70-68 | 3-3 | .500 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 7 | Sat Dec 4 | at Green Bay | W82-58 | 4-3 | .571 | - | | Resch Center · Ashwaubenon, WI |
| 8 | Wed Dec 8 | vs C Michigan | W84-77 | 5-3 | .625 | - | | Beeghly Center · Youngstown, OH |
| 9 | Sat Dec 11 | vs Canisius | W71-43 | 6-3 | .667 | - | | Beeghly Center · Youngstown, OH |
| 10 | Sat Dec 18 | vs TBD | W83-54 | 7-3 | .700 | - | | Beeghly Center · Youngstown, OH |
| 11 | Wed Dec 22 | at West Virginia | L52-82 | 7-4 | .636 | - | | WVU Coliseum · Morgantown, WV |
| 12 | Wed Dec 29 | vsTBD | W96-56 | 8-4 | .667 | - | | Beeghly Center · Youngstown, OH |
| 14 | Sat Jan 1 | at Oakland | L72-87 | 8-5 | .615 | - | | Athletics Center O'rena · Rochester, MI |
| 15 | Wed Jan 5 | at Robert Morris | W64-60 | 9-5 | .643 | - | | UPMC Events Center · Moon Township, PA |
| 16 | Fri Jan 7 | vs Purdue FW | L61-71 | 9-6 | .600 | - | | Beeghly Center · Youngstown, OH |
| 17 | Sun Jan 9 | vs Cleveland St | L80-86 (OT) | 9-7 | .563 | - | | Beeghly Center · Youngstown, OH |
| 18 | Thu Jan 13 | vs N Kentucky | L67-68 | 9-8 | .529 | - | | Beeghly Center · Youngstown, OH |
| 19 | Sat Jan 15 | vs Wright St | W90-87 | 10-8 | .556 | - | | Beeghly Center · Youngstown, OH |
| 20 | Fri Jan 21 | atCleveland St | L61-64 | 10-9 | .526 | - | | Wolstein Center · Cleveland, OH |
| 21 | Sun Jan 23 | atPurdue FW | L71-82 | 10-10 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 22 | Thu Jan 27 | vsGreen Bay | W63-50 | 11-10 | .524 | - | | Beeghly Center · Youngstown, OH |
| 23 | Sat Jan 29 | vsMilwaukee | W86-72 | 12-10 | .545 | - | | Beeghly Center · Youngstown, OH |
| 24 | Thu Feb 3 | at IU Indy | W61-55 | 13-10 | .565 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 25 | Sat Feb 5 | at UIC | W66-64 | 14-10 | .583 | - | | Credit Union 1 Arena · Chicago, IL |
| 26 | Wed Feb 9 | vsOakland | W78-71 | 15-10 | .600 | - | | Beeghly Center · Youngstown, OH |
| 27 | Fri Feb 11 | vs Detroit Mercy | W82-69 | 16-10 | .615 | - | | Beeghly Center · Youngstown, OH |
| 28 | Sun Feb 13 | vsRobert Morris | L68-73 | 16-11 | .593 | - | | Beeghly Center · Youngstown, OH |
| 29 | Thu Feb 17 | vsUIC | W88-79 | 17-11 | .607 | - | | Beeghly Center · Youngstown, OH |
| 30 | Sat Feb 19 | vsIU Indy | W74-61 | 18-11 | .621 | - | | Beeghly Center · Youngstown, OH |
| 31 | Thu Feb 24 | atWright St | L71-84 | 18-12 | .600 | - | | Nutter Center · Dayton, OH |
| 32 | Sat Feb 26 | atN Kentucky | L61-75 | 18-13 | .581 | - | | Truist Arena · Highland Heights, KY |
| 33 | Tue Mar 1 | vsRobert Morris | L73-77 | 18-14 | .563 | - | | Beeghly Center · Youngstown, OH |
| 34 | Wed Mar 16 | vs Morgan St | W70-65 | 19-14 | .576 | - | | Beeghly Center · Youngstown, OH |
| 36 | Wed Mar 23 | at Fresno St | L71-80 | 19-15 | .559 | - | | Save Mart Center · Fresno, CA |
Wofford