| 1 | Sat Oct 16 | at Oilers | L2-5 | 0-1-0 | 0 PTS | Rogers Place · Edmonton, AB |
| 2 | Mon Oct 18 | vsDucks | L2-3 (OT) | 0-1-1 | 1 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 3 | Thu Oct 21 | atRed Wings | W3-0 | 1-1-1 | 3 PTS | Little Caesars Arena · Detroit, MI |
| 4 | Sat Oct 23 | atCapitals | W4-3 (OT) | 2-1-1 | 5 PTS | Capital One Arena · Washington, D.C. |
| 5 | Mon Oct 25 | atRangers | W5-1 | 3-1-1 | 7 PTS | Madison Square Garden · Manhattan, NY |
| 6 | Tue Oct 26 | atDevils | W5-3 | 4-1-1 | 9 PTS | Prudential Center · Newark, NJ |
| 7 | Thu Oct 28 | atPenguins | W4-0 | 5-1-1 | 11 PTS | PPG Paints Arena · Pittsburgh, PA |
| 8 | Sat Oct 30 | vsFlyers | W4-0 | 6-1-1 | 13 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 9 | Tue Nov 2 | vsPredators | L2-3 (OT) | 6-1-2 | 14 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 10 | Thu Nov 4 | vsStars | L3-4 (OT) | 6-1-3 | 15 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 11 | Sat Nov 6 | vsRangers | W6-0 | 7-1-3 | 17 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 12 | Tue Nov 9 | vsSharks | L1-4 | 7-2-3 | 17 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 13 | Thu Nov 11 | atCanadiens | L2-4 | 7-3-3 | 17 PTS | Bell Centre · Montreal, QC |
| 14 | Fri Nov 12 | atMaple Leafs | L1-2 (OT) | 7-3-4 | 18 PTS | Scotiabank Arena · Toronto, ON |
| 15 | Sun Nov 14 | atSenators | W4-0 | 8-3-4 | 20 PTS | Canadian Tire Centre · Ottawa, ON |
| 16 | Tue Nov 16 | atFlyers | L1-2 (OT) | 8-3-5 | 21 PTS | Wells Fargo Center · Philadelphia, PA |
| 17 | Thu Nov 18 | atSabres | W5-0 | 9-3-5 | 23 PTS | KeyBank Center · Buffalo, NY |
| 18 | Sat Nov 20 | atIslanders | W5-2 | 10-3-5 | 25 PTS | UBS Arena · Elmont, NY |
| 19 | Sun Nov 21 | atBruins | W4-0 | 11-3-5 | 27 PTS | TD Garden · Boston, MA |
| 20 | Tue Nov 23 | vsBlackhawks | W5-2 | 12-3-5 | 29 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 21 | Sat Nov 27 | vsJets | L2-4 | 12-4-5 | 29 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 22 | Mon Nov 29 | vsPenguins | W2-1 (SO) | 13-4-5 | 31 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 23 | Thu Dec 2 | atKings | W3-2 | 14-4-5 | 33 PTS | Crypto.com Arena · Los Angeles, CA |
| 24 | Fri Dec 3 | atDucks | W4-3 (SO) | 15-4-5 | 35 PTS | Honda Center · Anaheim, CA |
| 25 | Sun Dec 5 | atKnights | L2-3 | 15-5-5 | 35 PTS | T-Mobile Arena · Las Vegas, NV |
| 26 | Tue Dec 7 | atSharks | L3-5 | 15-6-5 | 35 PTS | SAP Center · San Jose, CA |
| 27 | Thu Dec 9 | vsHurricanes | L1-2 (OT) | 15-6-6 | 36 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 28 | Sat Dec 11 | vsBruins | L2-4 | 15-7-6 | 36 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 29 | Thu Dec 30 | atKraken | W6-4 | 16-7-6 | 38 PTS | Climate Pledge Arena · Seattle, WA |
| 30 | Sun Jan 2 | atBlackhawks | W5-1 | 17-7-6 | 40 PTS | United Center · Chicago, IL |
| 31 | Tue Jan 4 | atPanthers | L2-6 | 17-8-6 | 40 PTS | Amerant Bank Arena · Sunrise, FL |
| 32 | Thu Jan 6 | atLightning | L1-4 | 17-9-6 | 40 PTS | AMALIE Arena · Tampa, FL |
| 33 | Fri Jan 7 | atHurricanes | L3-6 | 17-10-6 | 40 PTS | PNC Arena · Raleigh, NC |
| 34 | Thu Jan 13 | vsSenators | L1-4 | 17-11-6 | 40 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 35 | Tue Jan 18 | vsPanthers | W5-1 | 18-11-6 | 42 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 36 | Sat Jan 22 | atOilers | L3-5 | 18-12-6 | 42 PTS | Rogers Place · Edmonton, AB |
| 37 | Mon Jan 24 | vsBlues | W7-1 | 19-12-6 | 44 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 38 | Wed Jan 26 | atJackets | W6-0 | 20-12-6 | 46 PTS | Nationwide Arena · Columbus, OH |
| 39 | Thu Jan 27 | atBlues | L1-5 | 20-13-6 | 46 PTS | Enterprise Center · St. Louis, MO |
| 40 | Sat Jan 29 | vsCanucks | W1-0 (OT) | 21-13-6 | 48 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 41 | Tue Feb 1 | atStars | W4-3 | 22-13-6 | 50 PTS | American Airlines Center · Dallas, TX |
| 42 | Wed Feb 2 | atCoyotes | W4-2 | 23-13-6 | 52 PTS | Mullett Arena · Tempe, AZ |
| 43 | Wed Feb 9 | vsKnights | W6-0 | 24-13-6 | 54 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 44 | Thu Feb 10 | vsMaple Leafs | W5-2 | 25-13-6 | 56 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 45 | Sat Feb 12 | vsIslanders | W5-2 | 26-13-6 | 58 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 46 | Tue Feb 15 | vsJackets | W6-2 | 27-13-6 | 60 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 47 | Wed Feb 16 | vsDucks | W6-2 | 28-13-6 | 62 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 48 | Sat Feb 19 | vsKraken | W2-1 | 29-13-6 | 64 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 49 | Mon Feb 21 | vsJets | W3-1 | 30-13-6 | 66 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 50 | Thu Feb 24 | atCanucks | L1-7 | 30-14-6 | 66 PTS | Rogers Arena · Vancouver, British Columbia |
| 51 | Sat Feb 26 | vsWild | W7-3 | 31-14-6 | 68 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 52 | Tue Mar 1 | atWild | W5-1 | 32-14-6 | 70 PTS | Xcel Energy Center · St. Paul, MN |
| 53 | Thu Mar 3 | vsCanadiens | L4-5 (OT) | 32-14-7 | 71 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 54 | Sat Mar 5 | atAvalanche | W4-3 (OT) | 33-14-7 | 73 PTS | Ball Arena · Denver, CO |
| 55 | Mon Mar 7 | vsOilers | W3-1 | 34-14-7 | 75 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 56 | Tue Mar 8 | vsCapitals | L4-5 | 34-15-7 | 75 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 57 | Thu Mar 10 | vsLightning | W4-1 | 35-15-7 | 77 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 58 | Sat Mar 12 | vsRed Wings | W3-0 | 36-15-7 | 79 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 59 | Sun Mar 13 | atAvalanche | L0-3 | 36-16-7 | 79 PTS | Ball Arena · Denver, CO |
| 60 | Wed Mar 16 | vsDevils | W6-3 | 37-16-7 | 81 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 61 | Fri Mar 18 | vsSabres | L0-1 (OT) | 37-16-8 | 82 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 62 | Sat Mar 19 | atCanucks | W5-2 | 38-16-8 | 84 PTS | Rogers Arena · Vancouver, British Columbia |
| 63 | Tue Mar 22 | vsSharks | L3-4 | 38-17-8 | 84 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 64 | Fri Mar 25 | vsCoyotes | W4-2 | 39-17-8 | 86 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 65 | Sat Mar 26 | vsOilers | W9-5 | 40-17-8 | 88 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 66 | Tue Mar 29 | vsAvalanche | L1-2 | 40-18-8 | 88 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 67 | Thu Mar 31 | vsKings | L2-3 (SO) | 40-18-9 | 89 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 68 | Sat Apr 2 | vsBlues | L4-6 | 40-19-9 | 89 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 69 | Mon Apr 4 | atKings | W3-2 | 41-19-9 | 91 PTS | Crypto.com Arena · Los Angeles, CA |
| 70 | Wed Apr 6 | atDucks | W4-2 | 42-19-9 | 93 PTS | Honda Center · Anaheim, CA |
| 71 | Thu Apr 7 | atSharks | W4-2 | 43-19-9 | 95 PTS | SAP Center · San Jose, CA |
| 72 | Sat Apr 9 | atKraken | W4-1 | 44-19-9 | 97 PTS | Climate Pledge Arena · Seattle, WA |
| 73 | Tue Apr 12 | vsKraken | W5-3 | 45-19-9 | 99 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 74 | Thu Apr 14 | vsKnights | L1-6 | 45-20-9 | 99 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 75 | Sat Apr 16 | vsCoyotes | W9-1 | 46-20-9 | 101 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 76 | Mon Apr 18 | atBlackhawks | W5-2 | 47-20-9 | 103 PTS | United Center · Chicago, IL |
| 77 | Tue Apr 19 | atPredators | L2-3 (SO) | 47-20-10 | 104 PTS | Bridgestone Arena · Nashville, TN |
| 78 | Thu Apr 21 | vsStars | W4-2 | 48-20-10 | 106 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 79 | Sat Apr 23 | vsCanucks | W6-3 | 49-20-10 | 108 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 80 | Tue Apr 26 | atPredators | W5-4 (OT) | 50-20-10 | 110 PTS | Bridgestone Arena · Nashville, TN |
| 81 | Thu Apr 28 | atWild | L2-3 (OT) | 50-20-11 | 111 PTS | Xcel Energy Center · St. Paul, MN |
| 82 | Fri Apr 29 | atJets | L1-3 | 50-21-11 | 111 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 1 | Tue May 3 | vsStars | W1-0 | 1-0 | 1.000 | Scotiabank Saddledome · Calgary, Alberta |
| 2 | Thu May 5 | vsStars | L0-2 | 1-1 | .500 | Scotiabank Saddledome · Calgary, Alberta |
| 3 | Sat May 7 | atStars | L2-4 | 1-2 | .333 | American Airlines Center · Dallas, TX |
| 4 | Mon May 9 | atStars | W4-1 | 2-2 | .500 | American Airlines Center · Dallas, TX |
| 5 | Wed May 11 | vsStars | W3-1 | 3-2 | .600 | Scotiabank Saddledome · Calgary, Alberta |
| 6 | Fri May 13 | atStars | L2-4 | 3-3 | .500 | American Airlines Center · Dallas, TX |
| 7 | Sun May 15 | vsStars | W3-2 (OT) | 4-3 | .571 | Scotiabank Saddledome · Calgary, Alberta |
| 1 | Wed May 18 | vsOilers | W9-6 | 1-0 | 1.000 | Scotiabank Saddledome · Calgary, Alberta |
| 2 | Fri May 20 | vsOilers | L3-5 | 1-1 | .500 | Scotiabank Saddledome · Calgary, Alberta |
| 3 | Sun May 22 | atOilers | L1-4 | 1-2 | .333 | Rogers Place · Edmonton, AB |
| 4 | Tue May 24 | atOilers | L3-5 | 1-3 | .250 | Rogers Place · Edmonton, AB |
| 5 | Thu May 26 | vsOilers | L4-5 (OT) | 1-4 | .200 | Scotiabank Saddledome · Calgary, Alberta |
