| 1 | Thu Oct 13 | vs Avalanche | W5-3 | 1-0-0 | 2 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 2 | Sat Oct 15 | atOilers | W4-3 | 2-0-0 | 4 PTS | Rogers Place · Edmonton, AB |
| 3 | Tue Oct 18 | vsKnights | W3-2 | 3-0-0 | 6 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 4 | Thu Oct 20 | vsSabres | L3-6 | 3-1-0 | 6 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 5 | Sat Oct 22 | vsHurricanes | W3-2 (OT) | 4-1-0 | 8 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 6 | Tue Oct 25 | vsPenguins | W4-1 | 5-1-0 | 10 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 7 | Sat Oct 29 | vsOilers | L2-3 | 5-2-0 | 10 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 8 | Tue Nov 1 | vsKraken | L4-5 | 5-3-0 | 10 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 9 | Thu Nov 3 | vsPredators | L1-4 | 5-4-0 | 10 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 10 | Sat Nov 5 | vsDevils | L3-4 (OT) | 5-4-1 | 11 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 11 | Mon Nov 7 | atIslanders | L3-4 (OT) | 5-4-2 | 12 PTS | UBS Arena · Elmont, NY |
| 12 | Tue Nov 8 | atDevils | L2-3 | 5-5-2 | 12 PTS | Prudential Center · Newark, NJ |
| 13 | Thu Nov 10 | atBruins | L1-3 | 5-6-2 | 12 PTS | TD Garden · Boston, MA |
| 14 | Sat Nov 12 | vsJets | W3-2 | 6-6-2 | 14 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 15 | Mon Nov 14 | vsKings | W6-5 | 7-6-2 | 16 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 16 | Thu Nov 17 | atLightning | L1-4 | 7-7-2 | 16 PTS | AMALIE Arena · Tampa, FL |
| 17 | Sat Nov 19 | atPanthers | W5-4 (SO) | 8-7-2 | 18 PTS | Amerant Bank Arena · Sunrise, FL |
| 18 | Mon Nov 21 | atFlyers | W5-2 | 9-7-2 | 20 PTS | Wells Fargo Center · Philadelphia, PA |
| 19 | Wed Nov 23 | atPenguins | L1-2 (SO) | 9-7-3 | 21 PTS | PPG Paints Arena · Pittsburgh, PA |
| 20 | Fri Nov 25 | atCapitals | L0-3 | 9-8-3 | 21 PTS | Capital One Arena · Washington, D.C. |
| 21 | Sat Nov 26 | atHurricanes | L2-3 | 9-9-3 | 21 PTS | PNC Arena · Raleigh, NC |
| 22 | Tue Nov 29 | vsPanthers | W6-2 | 10-9-3 | 23 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 23 | Thu Dec 1 | vsCanadiens | L1-2 | 10-10-3 | 23 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 24 | Sat Dec 3 | vsCapitals | W5-2 | 11-10-3 | 25 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 25 | Mon Dec 5 | vsCoyotes | W3-2 | 12-10-3 | 27 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 26 | Wed Dec 7 | vsWild | W5-3 | 13-10-3 | 29 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 27 | Fri Dec 9 | atJackets | L1-3 | 13-11-3 | 29 PTS | Nationwide Arena · Columbus, OH |
| 28 | Sat Dec 10 | atMaple Leafs | L4-5 (OT) | 13-11-4 | 30 PTS | Scotiabank Arena · Toronto, ON |
| 29 | Mon Dec 12 | atCanadiens | L1-2 (SO) | 13-11-5 | 31 PTS | Bell Centre · Montreal, QC |
| 30 | Wed Dec 14 | vsCanucks | L3-4 (SO) | 13-11-6 | 32 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 31 | Fri Dec 16 | vsBlues | L2-5 | 13-12-6 | 32 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 32 | Sun Dec 18 | atSharks | W5-2 | 14-12-6 | 34 PTS | SAP Center · San Jose, CA |
| 33 | Tue Dec 20 | atSharks | W7-3 | 15-12-6 | 36 PTS | SAP Center · San Jose, CA |
| 34 | Thu Dec 22 | atKings | L3-4 (OT) | 15-12-7 | 37 PTS | Crypto.com Arena · Los Angeles, CA |
| 35 | Fri Dec 23 | atDucks | W3-2 (OT) | 16-12-7 | 39 PTS | Honda Center · Anaheim, CA |
| 36 | Tue Dec 27 | vsOilers | L1-2 | 16-13-7 | 39 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 37 | Wed Dec 28 | atKraken | W3-2 | 17-13-7 | 41 PTS | Climate Pledge Arena · Seattle, WA |
| 38 | Sat Dec 31 | vsCanucks | W3-2 | 18-13-7 | 43 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 39 | Tue Jan 3 | atJets | L2-3 | 18-14-7 | 43 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 40 | Fri Jan 6 | vsIslanders | W4-1 | 19-14-7 | 45 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 41 | Sun Jan 8 | atBlackhawks | L3-4 (OT) | 19-14-8 | 46 PTS | United Center · Chicago, IL |
| 42 | Tue Jan 10 | atBlues | L3-4 (OT) | 19-14-9 | 47 PTS | Enterprise Center · St. Louis, MO |
| 43 | Thu Jan 12 | atBlues | W4-1 | 20-14-9 | 49 PTS | Enterprise Center · St. Louis, MO |
| 44 | Sat Jan 14 | atStars | W6-5 | 21-14-9 | 51 PTS | American Airlines Center · Dallas, TX |
| 45 | Mon Jan 16 | atPredators | L1-2 | 21-15-9 | 51 PTS | Bridgestone Arena · Nashville, TN |
| 46 | Wed Jan 18 | vsAvalanche | L1-4 | 21-16-9 | 51 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 47 | Sat Jan 21 | vsLightning | W6-3 | 22-16-9 | 53 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 48 | Mon Jan 23 | vsJackets | W4-3 (OT) | 23-16-9 | 55 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 49 | Thu Jan 26 | vsBlackhawks | L1-5 | 23-17-9 | 55 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 50 | Fri Jan 27 | atKraken | W5-2 | 24-17-9 | 57 PTS | Climate Pledge Arena · Seattle, WA |
| 51 | Mon Feb 6 | atRangers | L4-5 (OT) | 24-17-10 | 58 PTS | Madison Square Garden · Manhattan, NY |
| 52 | Thu Feb 9 | atRed Wings | L1-2 | 24-18-10 | 58 PTS | Little Caesars Arena · Detroit, MI |
| 53 | Sat Feb 11 | atSabres | W7-2 | 25-18-10 | 60 PTS | KeyBank Center · Buffalo, NY |
| 54 | Mon Feb 13 | atSenators | L3-4 (OT) | 25-18-11 | 61 PTS | Canadian Tire Centre · Ottawa, ON |
| 55 | Thu Feb 16 | vsRed Wings | L2-5 | 25-19-11 | 61 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 56 | Sat Feb 18 | vsRangers | W3-2 (OT) | 26-19-11 | 63 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 57 | Mon Feb 20 | vsFlyers | L3-4 | 26-20-11 | 63 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 58 | Wed Feb 22 | atCoyotes | W6-3 | 27-20-11 | 65 PTS | Mullett Arena · Tempe, AZ |
| 59 | Thu Feb 23 | atKnights | L3-4 (OT) | 27-20-12 | 66 PTS | T-Mobile Arena · Las Vegas, NV |
| 60 | Sat Feb 25 | atAvalanche | L1-4 | 27-21-12 | 66 PTS | Ball Arena · Denver, CO |
| 61 | Tue Feb 28 | vsBruins | L3-4 (OT) | 27-21-13 | 67 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 62 | Thu Mar 2 | vsMaple Leafs | L1-2 | 27-22-13 | 67 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 63 | Sat Mar 4 | vsWild | L0-3 | 27-23-13 | 67 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 64 | Mon Mar 6 | atStars | W5-4 | 28-23-13 | 69 PTS | American Airlines Center · Dallas, TX |
| 65 | Tue Mar 7 | atWild | W1-0 (SO) | 29-23-13 | 71 PTS | Xcel Energy Center · St. Paul, MN |
| 66 | Fri Mar 10 | vsDucks | L1-3 | 29-24-13 | 71 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 67 | Sun Mar 12 | vsSenators | W5-1 | 30-24-13 | 73 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 68 | Tue Mar 14 | atCoyotes | L3-4 (OT) | 30-24-14 | 74 PTS | Mullett Arena · Tempe, AZ |
| 69 | Thu Mar 16 | atKnights | W7-2 | 31-24-14 | 76 PTS | T-Mobile Arena · Las Vegas, NV |
| 70 | Sat Mar 18 | vsStars | L5-6 (OT) | 31-24-15 | 77 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 71 | Mon Mar 20 | atKings | L2-8 | 31-25-15 | 77 PTS | Crypto.com Arena · Los Angeles, CA |
| 72 | Tue Mar 21 | atDucks | W5-1 | 32-25-15 | 79 PTS | Honda Center · Anaheim, CA |
| 73 | Thu Mar 23 | vsKnights | L2-3 | 32-26-15 | 79 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 74 | Sat Mar 25 | vsSharks | W5-3 | 33-26-15 | 81 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 75 | Tue Mar 28 | vsKings | W2-1 | 34-26-15 | 83 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 76 | Fri Mar 31 | atCanucks | W5-4 (OT) | 35-26-15 | 85 PTS | Rogers Arena · Vancouver, British Columbia |
| 77 | Sun Apr 2 | vsDucks | W5-4 | 36-26-15 | 87 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 78 | Tue Apr 4 | vsBlackhawks | L3-4 | 36-27-15 | 87 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 79 | Wed Apr 5 | atJets | W3-1 | 37-27-15 | 89 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 80 | Sat Apr 8 | atCanucks | L2-3 (SO) | 37-27-16 | 90 PTS | Rogers Arena · Vancouver, British Columbia |
| 81 | Mon Apr 10 | vsPredators | L2-3 (SO) | 37-27-17 | 91 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 82 | Wed Apr 12 | vsSharks | W3-1 | 38-27-17 | 93 PTS | Scotiabank Saddledome · Calgary, Alberta |
