| 1 | Tue Oct 12 | at Knights | L3-4 | 0-1-0 | 0 PTS | T-Mobile Arena · Las Vegas, NV |
| 2 | Thu Oct 14 | atPredators | W4-3 | 1-1-0 | 2 PTS | Bridgestone Arena · Nashville, TN |
| 3 | Sat Oct 16 | atJackets | L1-2 (OT) | 1-1-1 | 3 PTS | Nationwide Arena · Columbus, OH |
| 4 | Mon Oct 18 | atFlyers | L1-6 | 1-2-1 | 3 PTS | Wells Fargo Center · Philadelphia, PA |
| 5 | Tue Oct 19 | atDevils | L2-4 | 1-3-1 | 3 PTS | Prudential Center · Newark, NJ |
| 6 | Sat Oct 23 | vsCanucks | L2-4 | 1-4-1 | 3 PTS | Climate Pledge Arena · Seattle, WA |
| 7 | Tue Oct 26 | vsCanadiens | W5-1 | 2-4-1 | 5 PTS | Climate Pledge Arena · Seattle, WA |
| 8 | Thu Oct 28 | vsWild | W4-1 | 3-4-1 | 7 PTS | Climate Pledge Arena · Seattle, WA |
| 9 | Sun Oct 31 | vsRangers | L1-3 | 3-5-1 | 7 PTS | Climate Pledge Arena · Seattle, WA |
| 10 | Mon Nov 1 | atOilers | L2-5 | 3-6-1 | 7 PTS | Rogers Place · Edmonton, AB |
| 11 | Thu Nov 4 | vsSabres | W5-2 | 4-6-1 | 9 PTS | Climate Pledge Arena · Seattle, WA |
| 12 | Sat Nov 6 | atCoyotes | L4-5 | 4-7-1 | 9 PTS | Mullett Arena · Tempe, AZ |
| 13 | Tue Nov 9 | atKnights | L2-4 | 4-8-1 | 9 PTS | T-Mobile Arena · Las Vegas, NV |
| 14 | Thu Nov 11 | vsDucks | L4-7 | 4-9-1 | 9 PTS | Climate Pledge Arena · Seattle, WA |
| 15 | Sat Nov 13 | vsWild | L2-4 | 4-10-1 | 9 PTS | Climate Pledge Arena · Seattle, WA |
| 16 | Wed Nov 17 | vsBlackhawks | L2-4 | 4-11-1 | 9 PTS | Climate Pledge Arena · Seattle, WA |
| 17 | Fri Nov 19 | vsAvalanche | L3-7 | 4-12-1 | 9 PTS | Climate Pledge Arena · Seattle, WA |
| 18 | Sun Nov 21 | vsCapitals | W5-2 | 5-12-1 | 11 PTS | Climate Pledge Arena · Seattle, WA |
| 19 | Wed Nov 24 | vsHurricanes | W2-1 | 6-12-1 | 13 PTS | Climate Pledge Arena · Seattle, WA |
| 20 | Fri Nov 26 | atLightning | L0-3 | 6-13-1 | 13 PTS | AMALIE Arena · Tampa, FL |
| 21 | Sat Nov 27 | atPanthers | W4-1 | 7-13-1 | 15 PTS | Amerant Bank Arena · Sunrise, FL |
| 22 | Mon Nov 29 | atSabres | W7-4 | 8-13-1 | 17 PTS | KeyBank Center · Buffalo, NY |
| 23 | Wed Dec 1 | atRed Wings | L3-4 (SO) | 8-13-2 | 18 PTS | Little Caesars Arena · Detroit, MI |
| 24 | Fri Dec 3 | vsOilers | W4-3 | 9-13-2 | 20 PTS | Climate Pledge Arena · Seattle, WA |
| 25 | Mon Dec 6 | vsPenguins | L1-6 | 9-14-2 | 20 PTS | Climate Pledge Arena · Seattle, WA |
| 26 | Thu Dec 9 | vsJets | L0-3 | 9-15-2 | 20 PTS | Climate Pledge Arena · Seattle, WA |
| 27 | Sat Dec 11 | vsJackets | L4-5 (OT) | 9-15-3 | 21 PTS | Climate Pledge Arena · Seattle, WA |
| 28 | Tue Dec 14 | atSharks | W3-1 | 10-15-3 | 23 PTS | SAP Center · San Jose, CA |
| 29 | Wed Dec 15 | atDucks | L1-4 | 10-16-3 | 23 PTS | Honda Center · Anaheim, CA |
| 30 | Sat Dec 18 | vsOilers | L3-5 | 10-17-3 | 23 PTS | Climate Pledge Arena · Seattle, WA |
| 31 | Wed Dec 29 | vsFlyers | L2-3 (OT) | 10-17-4 | 24 PTS | Climate Pledge Arena · Seattle, WA |
| 32 | Thu Dec 30 | vsFlames | L4-6 | 10-18-4 | 24 PTS | Climate Pledge Arena · Seattle, WA |
| 33 | Sat Jan 1 | vsCanucks | L2-5 | 10-19-4 | 24 PTS | Climate Pledge Arena · Seattle, WA |
| 34 | Mon Jan 10 | atAvalanche | L3-4 | 10-20-4 | 24 PTS | Ball Arena · Denver, CO |
| 35 | Wed Jan 12 | atStars | L2-5 | 10-21-4 | 24 PTS | American Airlines Center · Dallas, TX |
| 36 | Thu Jan 13 | atBlues | L1-2 | 10-22-4 | 24 PTS | Enterprise Center · St. Louis, MO |
| 37 | Sat Jan 15 | vsKings | L1-3 | 10-23-4 | 24 PTS | Climate Pledge Arena · Seattle, WA |
| 38 | Mon Jan 17 | vsBlackhawks | W3-2 (SO) | 11-23-4 | 26 PTS | Climate Pledge Arena · Seattle, WA |
| 39 | Thu Jan 20 | vsSharks | W3-2 | 12-23-4 | 28 PTS | Climate Pledge Arena · Seattle, WA |
| 40 | Fri Jan 21 | vsBlues | L0-5 | 12-24-4 | 28 PTS | Climate Pledge Arena · Seattle, WA |
| 41 | Sun Jan 23 | vsPanthers | W5-3 | 13-24-4 | 30 PTS | Climate Pledge Arena · Seattle, WA |
| 42 | Tue Jan 25 | vsPredators | L2-4 | 13-25-4 | 30 PTS | Climate Pledge Arena · Seattle, WA |
| 43 | Thu Jan 27 | atPenguins | W2-1 (OT) | 14-25-4 | 32 PTS | PPG Paints Arena · Pittsburgh, PA |
| 44 | Sun Jan 30 | atRangers | L2-3 | 14-26-4 | 32 PTS | Madison Square Garden · Manhattan, NY |
| 45 | Tue Feb 1 | atBruins | L2-3 | 14-27-4 | 32 PTS | TD Garden · Boston, MA |
| 46 | Wed Feb 2 | atIslanders | W3-0 | 15-27-4 | 34 PTS | UBS Arena · Elmont, NY |
| 47 | Wed Feb 9 | vsCoyotes | L2-5 | 15-28-4 | 34 PTS | Climate Pledge Arena · Seattle, WA |
| 48 | Fri Feb 11 | atDucks | W4-3 | 16-28-4 | 36 PTS | Honda Center · Anaheim, CA |
| 49 | Mon Feb 14 | vsMaple Leafs | L2-6 | 16-29-4 | 36 PTS | Climate Pledge Arena · Seattle, WA |
| 50 | Thu Feb 17 | atJets | L3-5 | 16-30-4 | 36 PTS | Canada Life Centre · Winnipeg, Manitoba |
| 51 | Sat Feb 19 | atFlames | L1-2 | 16-31-4 | 36 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 52 | Mon Feb 21 | atCanucks | L2-5 | 16-32-4 | 36 PTS | Rogers Arena · Vancouver, British Columbia |
| 53 | Tue Feb 22 | vsIslanders | L2-5 | 16-33-4 | 36 PTS | Climate Pledge Arena · Seattle, WA |
| 54 | Thu Feb 24 | vsBruins | L2-3 (OT) | 16-33-5 | 37 PTS | Climate Pledge Arena · Seattle, WA |
| 55 | Sun Feb 27 | atSharks | L1-3 | 16-34-5 | 37 PTS | SAP Center · San Jose, CA |
| 56 | Wed Mar 2 | vsPredators | W4-3 | 17-34-5 | 39 PTS | Climate Pledge Arena · Seattle, WA |
| 57 | Sat Mar 5 | atCapitals | L2-5 | 17-35-5 | 39 PTS | Capital One Arena · Washington, D.C. |
| 58 | Sun Mar 6 | atHurricanes | L2-3 | 17-36-5 | 39 PTS | PNC Arena · Raleigh, NC |
| 59 | Tue Mar 8 | atMaple Leafs | L4-6 | 17-37-5 | 39 PTS | Scotiabank Arena · Toronto, ON |
| 60 | Thu Mar 10 | atSenators | L3-4 (OT) | 17-37-6 | 40 PTS | Canadian Tire Centre · Ottawa, ON |
| 61 | Sat Mar 12 | atCanadiens | W4-3 (SO) | 18-37-6 | 42 PTS | Bell Centre · Montreal, QC |
| 62 | Wed Mar 16 | vsLightning | L1-4 | 18-38-6 | 42 PTS | Climate Pledge Arena · Seattle, WA |
| 63 | Sat Mar 19 | vsRed Wings | W4-2 | 19-38-6 | 44 PTS | Climate Pledge Arena · Seattle, WA |
| 64 | Tue Mar 22 | atCoyotes | W4-2 | 20-38-6 | 46 PTS | Mullett Arena · Tempe, AZ |
| 65 | Sat Mar 26 | atKings | L2-4 | 20-39-6 | 46 PTS | Crypto.com Arena · Los Angeles, CA |
| 66 | Mon Mar 28 | atKings | W6-1 | 21-39-6 | 48 PTS | Crypto.com Arena · Los Angeles, CA |
| 67 | Wed Mar 30 | vsKnights | L0-3 | 21-40-6 | 48 PTS | Climate Pledge Arena · Seattle, WA |
| 68 | Fri Apr 1 | vsKnights | L2-5 | 21-41-6 | 48 PTS | Climate Pledge Arena · Seattle, WA |
| 69 | Sun Apr 3 | vsStars | W4-1 | 22-41-6 | 50 PTS | Climate Pledge Arena · Seattle, WA |
| 70 | Wed Apr 6 | atBlues | L1-4 | 22-42-6 | 50 PTS | Enterprise Center · St. Louis, MO |
| 71 | Thu Apr 7 | atBlackhawks | W2-0 | 23-42-6 | 52 PTS | United Center · Chicago, IL |
| 72 | Sat Apr 9 | vsFlames | L1-4 | 23-43-6 | 52 PTS | Climate Pledge Arena · Seattle, WA |
| 73 | Tue Apr 12 | atFlames | L3-5 | 23-44-6 | 52 PTS | Scotiabank Saddledome · Calgary, Alberta |
| 74 | Sat Apr 16 | vsDevils | W4-3 (SO) | 24-44-6 | 54 PTS | Climate Pledge Arena · Seattle, WA |
| 75 | Mon Apr 18 | vsSenators | W4-2 | 25-44-6 | 56 PTS | Climate Pledge Arena · Seattle, WA |
| 76 | Wed Apr 20 | vsAvalanche | W3-2 | 26-44-6 | 58 PTS | Climate Pledge Arena · Seattle, WA |
| 77 | Fri Apr 22 | atWild | L3-6 | 26-45-6 | 58 PTS | Xcel Energy Center · St. Paul, MN |
| 78 | Sat Apr 23 | atStars | L2-3 | 26-46-6 | 58 PTS | American Airlines Center · Dallas, TX |
| 79 | Tue Apr 26 | atCanucks | L2-5 | 26-47-6 | 58 PTS | Rogers Arena · Vancouver, British Columbia |
| 80 | Wed Apr 27 | vsKings | L3-5 | 26-48-6 | 58 PTS | Climate Pledge Arena · Seattle, WA |
| 81 | Fri Apr 29 | vsSharks | W3-0 | 27-48-6 | 60 PTS | Climate Pledge Arena · Seattle, WA |
| 82 | Sun May 1 | atJets | L3-4 | 27-49-6 | 60 PTS | Canada Life Centre · Winnipeg, Manitoba |
