| 1 | Wed Nov 25 | at 16UNC | L60-79 | 0-1 | .000 | - | ACC Network | Dean E. Smith Center · Chapel Hill, NC |
| 2 | Sat Nov 28 | vsTBD | W99-59 | 1-1 | .500 | - | | TD Arena · Charleston, SC |
| 4 | Sat Dec 5 | vsFurman | L57-81 | 1-2 | .333 | - | | TD Arena · Charleston, SC |
| 5 | Wed Dec 9 | vsMarshall | L72-84 | 1-3 | .250 | - | | TD Arena · Charleston, SC |
| 6 | Fri Dec 11 | vsSC State | W90-63 | 2-3 | .400 | - | | TD Arena · Charleston, SC |
| 7 | Fri Dec 18 | vsW Carolina | L70-76 (OT) | 2-4 | .333 | - | | TD Arena · Charleston, SC |
| 8 | Mon Dec 21 | atGeorgia St | L55-72 | 2-5 | .286 | - | | GSU Convocation Center · Atlanta, GA |
| 9 | Sat Jan 2 | atDelaware | L67-70 | 2-6 | .250 | - | | Bob Carpenter Center · Newark, DE |
| 10 | Sun Jan 3 | atDelaware | W66-59 | 3-6 | .333 | - | | Bob Carpenter Center · Newark, DE |
| 11 | Sat Jan 9 | vsDrexel | W61-60 | 4-6 | .400 | - | | TD Arena · Charleston, SC |
| 12 | Sun Jan 10 | vsDrexel | W73-68 | 5-6 | .455 | - | | TD Arena · Charleston, SC |
| 13 | Sat Jan 16 | vsNortheastern | L62-67 | 5-7 | .417 | - | | TD Arena · Charleston, SC |
| 14 | Sun Jan 17 | vsNortheastern | L66-68 | 5-8 | .385 | - | | TD Arena · Charleston, SC |
| 15 | Sun Jan 24 | atWilliam & Mary | PPD | 9-10 | .474 | - | | Kaplan Arena · Williamsburg, VA |
| 17 | Sat Feb 6 | vsTowson | W90-88 (2OT) | 6-8 | .429 | - | | TD Arena · Charleston, SC |
| 18 | Sun Feb 7 | vsTowson | W66-53 | 7-8 | .467 | - | | TD Arena · Charleston, SC |
| 19 | Sat Feb 13 | vsElon | W71-53 | 8-8 | .500 | - | | TD Arena · Charleston, SC |
| 20 | Sun Feb 14 | vsElon | L55-66 | 8-9 | .471 | - | | TD Arena · Charleston, SC |
| 21 | Sat Feb 20 | vsTBD | W86-83 (OT) | 9-9 | .500 | - | | TD Arena · Charleston, SC |
| 23 | Sun Mar 7 | vsDrexel | L75-80 | 9-10 | .474 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
