| 2 | Sat Nov 28 | at Pitt | L74-83 | 0-1 | .000 | - | | Petersen Events Center · Pittsburgh, PA |
| 3 | Wed Dec 2 | atQuinnipiac | W66-48 | 1-1 | .500 | - | | M&T Bank Arena · Hamden, CT |
| 4 | Thu Dec 3 | vsQuinnipiac | W70-58 | 2-1 | .667 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 5 | Sun Dec 6 | vsCoppin St | W69-54 | 3-1 | .750 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 6 | Sat Dec 12 | vsLa Salle | L48-58 | 3-2 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 7 | Thu Dec 17 | vsSaint Joseph's | W81-77 | 4-2 | .667 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 8 | Sat Dec 19 | atFairleigh | W85-68 | 5-2 | .714 | - | | Stratis Arena at the Rothman Center · Teaneck, NJ |
| 12 | Sat Jan 9 | atCharleston | L60-61 | 5-3 | .625 | - | | TD Arena · Charleston, SC |
| 13 | Sun Jan 10 | atCharleston | L68-73 | 5-4 | .556 | - | | TD Arena · Charleston, SC |
| 14 | Sat Jan 16 | vsWilliam & Mary | W82-58 | 6-4 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 15 | Sun Jan 17 | vsWilliam & Mary | L64-69 | 6-5 | .545 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 16 | Sat Jan 23 | atWilliam & Mary | W79-64 | 7-5 | .583 | - | | Kaplan Arena · Williamsburg, VA |
| 19 | Sun Jan 31 | atJMU | L64-73 | 7-6 | .538 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 20 | Sat Feb 6 | atHofstra | W73-71 | 8-6 | .571 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 21 | Sun Feb 7 | atHofstra | L74-79 | 8-7 | .533 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 26 | Fri Feb 26 | atJMU | W84-78 | 9-7 | .563 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 27 | Sun Mar 7 | atCharleston | W80-75 | 10-7 | .588 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 28 | Mon Mar 8 | atNortheastern | W74-67 | 11-7 | .611 | - | CBS | Atlantic Union Bank Center · Harrisonburg, VA |
| 29 | Tue Mar 9 | vsElon | W63-56 | 12-7 | .632 | - | CBS | Atlantic Union Bank Center · Harrisonburg, VA |
| 30 | Fri Mar 19 | at#1Illinois | L49-78 | 12-8 | .600 | #16 | TBS | Indiana Farmers Coliseum · Indianapolis, IN |
